Séminaire du Prof. Ion PETRE, le 23 octobre 2018, 10h30, site IBGBI
Network controllability: theory and applications Abstract: The intrinsic robustness of living systems against perturbations is a key factor that explains why many single-target drugs have been found to provide poor efficacy or to lead to significant side effects. Rather than trying to design selective ligands that target individual receptors only, network polypharmacology aims to modify multiple cellular