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Medical steroid's baffling connection to osteoporosis becomes clearer | The Source | Washington University in St. Louis
Dark areas (marked with arrows) in the first image show a process of bone renewal and strengthening. The second image shows a reduction in this process after a cortisone injection.Scientists are closing in on the solution to a persistent medical puzzle: why do high doses of cortisone, widely prescribed for asthma, rheumatoid arthritis and other inflammatory and autoimmune conditions, weaken bones? Researchers at the School of Medicine have identified osteoclasts, cells that dismantle old bone, as the essential link between osteoporosis and cortisone.