Suppositories — Hemp Extract (50 mg CBD/ea) » Quality Plus Essentials, Inc.
There are many advantages to the rectal administration of cannabis compared to other routes of absorption. If the oral route is disallowed, due to oral intake restrictions frequently required both before and after surgery, or impaired due to vomiting, injured jaw or throat, or gastrointestinal difficulties, it is still possible to administer cannabis rectally. Rectal administration of cannabis makes it possible to avoid drug degradation in the gastrointestinal tract by bypassing the first-pass metabolism in the liver. This allows the cannabinoids to reach the blood in much higher concentrations. Rectal administration avoids these effects, and a greater proportion of CBD is allowed to reach the blood stream. This form of administration offers a much faster uptake than oral administration (approximately 10 minutes, on average). The speed and reliability of uptake, combined with circumvention of many issues surrounding both ingestion and inhalation, makes rectal application an excellent addition to both new and pre-existing therapeutic regimens. With suppositories, initial effects will most often be noticed within 10-15 minutes after application, which will usually last 4-8 hours depending on the physiology and tolerance for cannabis in the individual. However, there are several issues that can slow absorption from the rectum to the blood stream. Diarrhea, fecal matter and tumors/cysts on the rectum wall can slow or prevent the cannabinoids from being absorbed. Rectal dehydration can also drastically reduce the effectiveness of suppositories; staying well hydrated by maintaining a healthy consumption of both water and electrolytes may prevent this. However, specific medical conditions may also cause rectal dehydration, in which case the solution may not be as simple. In case of concern, a medical professional should be consulted. Suppositories can be used to refine existing therapeutic regimens to greater effects. Those who have been prevented from using cannabis, due to inability to administer via ingestion or inhalation, can potentially derive benefit from cannabis for the first time by using cannabis suppositories.