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Improved efficacy of pregabalin by restoring plasma vitamin D levels in migraine: a case report.
Antonio Siniscalchi, MD; Piergiorgio Lochner; Erika Cione, PhD; Adelia Michniewicz, Biotechnologist; Vincenzo Guidetti, MD; Luca Gallelli, MD Abstract Migraine appears to be the most common neurological syndrome in primary care. Pain in migraine is mediated by the release of inflammatory mediators at the level of nerves and blood vessels. The antioxidant and neuroprotective effects of vitamin D in the central nervous system