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Integrative medicine for coronary artery disease works – provided your trial is fatally flawed
The objective of this 'real world' study was to evaluate the effectiveness of integrative medicine (IM) on patients with coronary artery disease (CAD) and investigate the prognostic factors of CAD in a real-world setting. A total of 1,087 hospitalized patients with CAD from 4 hospitals in Beijing, China were consecutively selected between August 2011 and February 2012. The patients were assigned to two groups: Chinese medicine (CM) plus conventional treatment, i.e., IM therapy (IM group). IM therapy meant that the patients accepted the conventional treatment of Western medicine and the treatment of Chinese herbal medicine including herbal-based injection and Chinese patent medicine as well as decoction for at least 7 days in the hospital or 3 months out of the hospital. Conventional treatment alone (CT group). The endpoint was a major cardiac event [MCE; including cardiac death, myocardial infarction (MI), and the need for revascularization]. A total of 1,040 patients finished the