Architecture and Stoichiometry of the E. coli DNA Helicase•Bacteriophage λP Complex
Cells must accurately replicate their DNA during cellular division. A recent structural study has determined how a bacterial DNA replication helicase complex is loaded unto DNA yielding insights into the early stages of DNA replication. NCDIR researchers from the Chait lab contributed to this structural work by performing native mass spectrometry (MS) and cross-linking MS