4/10/21

I got my COVID vaccine yesterday and man did it wipe me out. Thankfully, I didn’t start feeling bad until 7 hours after I got the shot, so I was able to get a lot of work done before then. I basically felt like I had the flu really bad, and it lasted all night. When I thought about it though, I’m even more thankful for the vaccine now because I know the alternative must be much worse. Thank you to the doctors and scientists who worked tirelessly this year.

P.S. I can’t wait till I don’t have to live in the dorm rooms and my lighting and desk area can be better. Then I can take better pictures:)

As a genetist, seeing people say "just use punnet squares" to explain a feature bothers me greatly.

DNA aint that simple. Just using a biology book from highschool as a source is not gonna make you an expert on the theme.

A lot of DNA traits dont follow Mendelian laws. Heck, DNA has the ability to move itself within a same chromosome, did you know that? That it can turn itself on and off just because?

Punnet squares are simpler for kids. But just because you know how to pair a couple of letters doesnt mean you know how genetical heritance works. I beg you to do a bigger research.

4/7/21

We are learning about behavioral genetics right now in my genetics class, and I find this topic so fascinating! Behavior is mainly determined from the environment. However, I think the potential for looking into genes that affect mental health is really cool for it can help us in creating treatments. Genetics is definitely my favorite class of the semester.

Also, this blackberry mint lemonade was amazing!

🎧 piano versions of Studio Ghibli soundtracks

These are so good to study to because they are nice background noise like LoFi, but they give me a definite happy vibe ☀️

Anonymous asked:

While I always found it interesting have far more complicated genetics are I admit it is unlikely I'll completely understand it. Though it is intriguing how sometimes how they express (I apologize for my simplicity in describing this) certain traits that otherwise appear absent in relatives, such as red hair.

It also leads to irritation when people claim baseless claims or treat people as an oddity (or just complain in the case of media) b/c they don't understand as you pointed out how complex it really is.

Sorry to ramble on here.

Dont worry, i get ya. Not even us who study genetics understand DNA/RNA completly. That’s why we always work with stadistics, with possibilities. Uncertainity. And yes, it’s rather fun trying to guess what can happen and how can some traits will/would express in the future, or even trying to understand how it worked in the past.

And yes, it irritates me greatly, specially when some people go “these two people dont look related because i did my punnet square”, or as you said, claim odditiy in certain treats (like “this person cant have blue eyes because their parents have brown eyes”) because they dont get how genes work.

Genetics are fun but also can be very cryptic and chaotic

Whereas before CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), gene therapy on humans was only achieving 2% correction, the genome of 80% of the cells in a subject can now be 'corrected' or reengineered. If desired, this can included the cells of germ-line generic material, such as sperm and eggs, which would pass on any genetically engineered change down onto the offspring of the human subject of the CRISPR editing. Not surprisingly, in 2015 China became the first country in which scientists legally and openly began editing human embryos using CRISPR. CCR5 was the gene targeted in the first human embryos edited in China. It is the receptor for HIV, and removing it from the genome of the edited embryos immunized the genetically engineered children against the AIDS virus.

Jason Reza Jorjani, “Prometheism” (2020).

Introducing - Feliquest!

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Feliquest is an upcoming browser-based game focused on building your own clowder of genetically accurate feral cats. Featuring gorgeous habitats to explore and build your home in, an expansive tile-based patrol system, a setting with its own rich lore, and helpful NPCs to guide your paws. Feliquest aims for a fun, casual gameplay experience and a friendly, inclusive community of people to interact with.

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This project is being developed by Cryptofelis Studios, a three person team consisting of our head programmer, Avery, head artist, Trey, and publicist, Quinn. Currently only a few months in development, our current focus is setting up a cat creator demo featuring a few of the colors and markings that will be available on launch. While the demo will be in a slightly different style than the official game art for now, it will allow us to get a head start on designing our layering system and better figuring out our code, as well as additionally giving you something fun to play with as we work! Above is a better, albeit still early, example of what the final art will resemble, a more stylized look with softer lines.

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If you’d like to support this game, the most helpful thing to do right now is just spread the word- while we plan to host a kickstarter eventually, we aren't quite ready to do that yet- we'd like to set a few more things up first, and until then, building interest is most important. So, share us around! Likes, comments, and shares will help us build our community in preparation for fundraising, feedback polls, and interest checks for potential features. Check out our linktree for our other socials and join discord server!

Convoluted Cleaning

Your kidneys are master cleaners. They filter your blood, clearing out waste products and absorbing vital nutrients and water. Needless to say, this is a complex task that involves an intricate system of tubes and ducts, including structures called the proximal convoluted tubules (PCTs). Researchers now investigate the architecture of PCTs, focusing on a protein called CAMSAP3. CAMSAP3 regulates the formation of a network of proteins called microtubules, which give cells their shape. CAMSAP3 was already known to regulate the structure of epithelial cells lining the intestines. Here researchers show that it also regulates the structure of PCTs. In mice with a mutated Camsap3 gene, scanning electron microscopy of their kidneys revealed that the PCTs were severely dilated (right) compared to normal mice PCTs (left). Mutant PCTs also had cysts and flattened epithelial cells with disorganised microtubules. CAMSAP3 is therefore vital in forming the elaborate structure of the PCT.

Written by Lux Fatimathas

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playing around with image j and I made a cool animation from my z stack! this is a pectoral fin from a transgenic fli1a:eGFP double homozygous mutant. this transgene helps visualize vasculature. actinodin mutants such as this one have defects in their fin rays, and given that vasculature develops in conjunction with the fin rays, the vessels may exhibit defects as well. it looks like that’s what’s happening here!