I get that some of y'all are really against pharmaceuticals and even I agree that many are over prescribed. but honestly. think carefully before you tell someone not to take antidepressants, or antipsychotics, or mood stabilizers, or whatever, because of your beliefs. many people taking these medications do so because without it they may be a danger to themselves, or others. if you don’t know their situation, then don’t bring your big pharma shit into it, because severe mental illness doesn’t give a fuck about big pharma. I mean, sure, people can have success with alternative, natural methods. and it’s not to say that these methods are not credible, but they are also not for everyone, and you should be conscious of this fact before playing internet psychiatrist.
What Happens When You Choose to Stop a Medicine on Your Own? 2/19/2016
This is a really, really, important post. I’m writing it not just so I have something to refer back to, but also in hopes that this will encourage more people to take their medicine on time and every day in order to stay in top health.
So what could happen if you don’t take your meds? A lot of people may assume you can get by just fine by going cold turkey off a medicine (by “cold turkey” I mean completely stopping taking the medicine very suddenly). I admit, I’m guilty of thinking this way, too (as recently as yesterday morning!). But I’m telling you the honest truth when I say choosing to go cold turkey off medicine is a very, seriously dangerous thing. Let me tell you some stories about when I’ve gone off certain meds:
1) Xanax. Xanax is in a class of medicine called benzodiazepines, commonly referred to as “benzos”. In March of 2015, towards the end of the month, I was admitted to a psych ward. The doctor there took me off all my meds and put me on solely Xanax, 0.5mg four times daily. The Xanax kept me calm, but it did nothing to quell my psychotic symptoms. So the doctor put me on an antipsychotic called Loxapine and continued the Xanax four times a day. I got out of the hospital April 2 after 10 days in the psych ward. I had only received two doses of my Xanax that day. I got all my prescriptions filled and went home. This doctor, we’ll call him Dr. M, and I never, ever got along. I assumed I knew better about what I needed than he did. So, I assumed “Hey, I’m on antipsychotics again. I don’t need Xanax!” So I stopped it cold turkey right then and there. Three days later, on April 5th, at my boyfriend’s parents’ house, I had a seizure at the breakfast table. I remember finishing my waffles and fruit for breakfast, then the next moment paramedics were examining me and I had no idea what the hell was going on. I asked my boyfriend why there were paramedics looking at me, and he said “Brigette, you had a seizure.” I didn’t remember anything that had happened in the last 20 minutes. My mom came and took me to the hospital where I stayed the next two nights and got out April 8th. Needless to say, that was shitty time spent. But the worst part? In Michigan, the law says a person cannot drive for 6 months after losing consciousness. So, in my decision that I was smarter than my doctor, I had a seizure on Easter morning, spent three days in a hospital, and lost my independence for 6 months.
2) Latuda and Geodon. February of 2015, I was taking both Latuda and Geodon (I actually am on the same combination again, but at different times during the day). One day late that month, I got pretty suicidal. Not enough to attempt, but enough to seriously consider ending my life. So I was admitted to a psych ward. That night, I was not given either Latuda or Geodon. It was easily the most bizarre night of my life. I had no clue what was going on. My reality was very, very distorted. I was talking to inanimate objects and shadows, going so far as to name them and give them personalities (the only one I clearly remember was Jamison, the shadow caused by a box of tissues on the nightstand). I went to pull my blankets over my body so I could sleep, but I was severely hallucinating and the blanket looked like it was alive. In a fit of rage, I threw my blanket to the ground and kicked it, trying to make it stop moving. I eventually gave up and went to lie down on my bed. I slept for a little while, and woke up feeling different. I thought the hospital staff had injected some kind of serum into my brain while I slept to make me feel different. Now I was really, really enraged. I almost went out into the hallway, yelling, “What are you doing, giving me living blankets and putting stuff in my head while I sleep?! WHAT?!” But I knew the rules of psych wards even at my most psychotic moments, so I kept my mouth shut and laid on my bed, very cold and shivering because I refused to use the “living” blanket (It would take three nights for me to be convinced that the blanket was not alive and was not trying to kill me). The next day, I was hardly able to function. I could not eat, I could not keep my head up, I was not very responsive when people talked to me. Keep in mind this was all withdrawal from not having the meds for one night. Eventually I was put on Trilafon and discharged. But that night without my meds has stuck with me very clearly about a year later.
3) Various other meds, such as Loxapine, Geodon, Latuda, and other antispychotics. Going off these meds has lead me to do dangerous things like cut my arm in a severe delusion, eat very little, drink very little, sleep very little, and make my symptoms get worse for days even after I get back on the med.
I could post a little more, but I don’t want this post to be too long. My point in telling these stories is that very serious and dangerous physical, emotional and mental side effects can occur if you do not take your medicine as prescribed by your doctor. I am telling you this as someone who has suffered those different types of side effects. I’m not trying to scare you into take your meds, but I want you to be well aware of what could happen if you choose to risk your health by not listening to your doctor.
My best advice to you is:
1) Find a psychiatrist you get along with, trust, and who knows you and your reaction to certain meds.
2) Take your meds as prescribed by that psychiatrist.
3) If a med seems to not be working or causing undesirable side effects, talk to your doctor before stopping it. It may be a med where the best way to get off it is to slowly taper your intake of it until it reaches zero.
These three steps will keep you safe, healthy, and on the road to a quicker recovery from your illness.
What do anti-psychotics do to people who aren't hallucinating? What happens in the long term? What if you suddenly stop taking them? My character is 28 and has been on anti-psychotics since he was 14 because he actually was seeing monsters but obviously nobody believed him and thus, drugs. If he stfu and took the pills (because due to Plot, they actually did mute the monster thing significantly), how likely is it he'd still be on them at 28? What would happen if he suddenly went cold turkey?
Being honest, Anon, your character is looking at some serious side effects. Here are some of the most notable / dangerous ones:
Feelings of inner restlessness
Tardive dyskinesia (which is irreversible, even if your character stops taking the medication!) I can go into TD in more detail if y’all want - I did a presentation on it recently!
Type II diabetes
Other important side effects:
Sedation (often extreme)
Increased chance for arrhythmia (with specific drugs)
And those are just the really serious ones! There’s a lot of other different ones too.
Certain classes of antipsychotics are more associated with different symptoms. For instance, the typical antipsychotics are more associated with movement symptoms, and atypical ones with metabolic ones. That’s not to say that an atypical antipsychotic can’t cause movement symptoms - it just does so at a much lower rate than a typical antipsychotic does.
Something really important to note - your character would likely not be on antipsychotics continuously for 14 years straight. Usually, a year or two after the first episode of psychosis, they’ll try to taper down and see if the antipsychotic is still necessary. If they have another episode, they’d go back on it, and they’d reevaluate after 3-5 years.
Oh, another thing - nowadays a lot of people taking antipsychotics long term actually don’t take pills; they get an injection. How frequently they get the shot depends on the drug, but it ranges from once every two weeks to once every three months.
Going cold turkey will indeed cause withdrawal symptoms - these symptoms are more specific to the drug in question.
Do Antipsychotic Medications Affect Cortical Thinning?
People diagnosed with
schizophrenia critically rely upon treatment with antipsychotic medications to
manage their symptoms and help them function at home and in the workplace.
But despite their benefits, antipsychotic
medications might also have some negative effects on brain structure or
function when taken for long periods of time.
In fact, “the role played by
antipsychotic treatment on the pathophysiologic trajectory of brain
abnormalities in schizophrenia is currently a matter of lively debate,”
explains Dr. Antonio Vita, Professor of Psychiatry at the
University of Brescia, Director of the Psychiatric Unit at Spedali Civili
Hospital, and first author on a study addressing this topic in the current
issue of Biological Psychiatry.
It is clear from
cross-sectional and longitudinal magnetic resonance imaging studies that
patients with schizophrenia show progressive structural brain abnormalities. The
findings indicate that lower gray matter volume or greater gray matter loss over
time are associated with the duration of antipsychotic treatment or cumulative antipsychotic
However, most of this prior
literature did not take into account the potential impact of whether a patient
was prescribed first-generation or second-generation antipsychotics. These two
classes of drugs are equally effective treatments, but have different
pharmacological properties and therefore, work differently in the body.
Vita and his colleagues
compiled data from eighteen imaging studies, resulting in a total of 1155
patients with schizophrenia and 911 healthy control subjects, in order to
evaluate the influence of antipsychotic type on gray matter changes over time.
As expected, their analysis
confirmed that patients with schizophrenia show progressive cortical gray
matter loss relative to healthy controls, which is related to cumulative antipsychotic intake
during the interval between imaging scans.
Interestingly, greater gray matter loss was correlated with higher mean
daily dose in studies including patients treated with first-generation
antipsychotics, whereas the opposite effect, i.e., less progressive loss, was
observed in studies including only patients treated with second-generation
This is consistent with the results of several studies in animals
and some clinical studies with patients indicating that second-generation
antipsychotics may have a neuroprotective effect on the brain.
“The possibility that
antipsychotic medications might have long-term effects on brain structure or
function that might be beneficial or detrimental is an important issue
deserving further study as many people treated with these medications will
remain on them for several decades,” said Dr. John Krystal, Editor of Biological Psychiatry.
“Although this is a clinically meaningful result, many issues remain to
be clarified: for instance, we
still do not know whether the effects on the brain of antipsychotics vary as a
function of age and stage of illness, or whether they may occur only when a
certain threshold of exposure (daily dose or cumulative dose) is reached,”
“Clarification of these
issues will have crucial importance in the clinical management of schizophrenia
and will allow a better understanding of the mechanisms underlying the
progression of structural brain abnormalities in the disease.”
Researchers Use Brain Scans to Predict Response to Antipsychotic Medications
Investigators at The Feinstein Institute for Medical Research have
discovered that brain scans can be used to predict patients’ response to
antipsychotic drug treatment. The findings are published online in the
latest issue of The American Journal of Psychiatry.
Psychotic disorders, such as schizophrenia and bipolar disorder, are
characterized by delusions, hallucinations, and disorganized thoughts
and behavior. They are estimated to occur in up to three percent of the
population and are a leading cause for disability worldwide. Psychotic
episodes are currently treated with antipsychotic drugs, but this
treatment is given without guidance from lab tests or brain scans, such
as functional magnetic resonance imaging or functional MRI (fMRI).
Doctors often use “trial-and-error” when choosing treatment for
psychotic disorders, without knowing if patients will respond well. This
lack of knowledge places a large burden on not only patients and their
families, but also healthcare professionals and healthcare systems.
Led by Anil Malhotra, MD, director of psychiatry research at Zucker Hillside Hospital and an investigator at the Feinstein Institute, and Todd Lencz, PhD,
associate investigator at the Zucker Hillside Hospital and the
Feinstein Institute, researchers used fMRI scans obtained before
treatment to predict ultimate response to medications in patients
suffering from their first episode of schizophrenia. Connectivity
patterns of a region of the brain called the striatum, which tends to be
atypical in patients suffering from psychotic disorders, were used to
create an index. This index significantly predicted if psychotic
symptoms were decreased in the studies’ patients. What’s even more
significant is that the researchers applied this index to confirm their
results in a separate group of patients with more chronic illness –
those who were hospitalized for psychotic symptoms. They found that
treatment outcome could be predicted in the replication group as well.
“This study is the first to report a predictive fMRI-derived measure
validated in an independent study group of patients treated with
antipsychotics,” said Deepak Sarpal, MD, a lead author of the study.
“The results we found from this study open the door for contemporary
‘precision medicine’ approaches to psychiatry, and more specifically,
the use of fMRI scans as important players in the treatment of
Check out this video for some examples! (Note - there is a full description of this video behind the jump at the end of this post. Feel free to use the way I describe the movements in your own writing!).
While TD is usually pretty noticeable, it can be subtle in the early stages (note the lip puckering in #5 and the cheek muscle in #7 in the video above).
Symptoms of TD get worse when the person is more emotional, and they mostly disappear when the person is asleep.
What causes TD?
The current theory is that TD is caused by a dopamine blockade at the D2 receptors, which causes a compensatory supersensitivity to dopamine.
I know I’ve lost you. Hell, a few months ago I would have been lost too!
So I have a story that will (hopefully) clear things up a little.
Reece has just gotten a new roommate, Anne. This is a pretty sweet deal for Reece, as he gets to save money and thus overall improve his quality of life.
However, it soon becomes clear that Reece and Anne aren’t a good fit. Anne is a bit of a slob and doesn’t do chores.
While he at first tidied up after her, Reece eventually can’t take it anymore. He confronts Anne, and she doesn’t take it well. She tells him that she’s not going to change, and that if her messiness bothers him, he should just clean up her messes for her.
After this conversation, Reece and Anne are no longer on friendly terms with one another, and now resent each other so much that they’ll never be able to be friends again.
Now, the little things that Reece used to let slide (like leaving dishes in the sink) become grounds for a screaming argument. He has become supersensitive to the things Anne does, and the slightest thing can activate his rage. The longer Reece lives with Anne, the worse things are going to get.
Reece eventually kicks Anne out and tries to find a new roommate. However, Reece’s normal state now is that of being supersensitive; even though Anne is gone, he’s still wary of future roommates, just in case they’re going to be like Anne. Reece becomes so intolerant of messiness that he’ll even yell at his friends and family if they so much as track a tiny bit of mud into the house or leave a cup on the table.
After living with Anne, Reese’s low tolerance for messiness never goes away.
Reese is your D2 Receptors and Anne is an antipsychotic. The “messes” Reese cleans up is dopamine. Reese’s permanent low tolerance for messiness is compensatory supersensitivity to dopamine. The angry outbursts whenever Reese has to deal with messes are what cause tardive dyskinesia.
There are a number of factors that can increase the risk of developing TD, but the most important one is how old the character is. Elderly people are ~3 times more likely than younger people to develop TD.
Another big risk factor is what medication your character is taking, as well as how big a dosage it is.
Older antipsychotics (aka typical antipsychotics) like haliperidol (Haldol) and chlorpromazine (Thorazine) are associated with high rates of causing TD. While generally atypical antipsychotics don’t cause TD at anywhere near the same rate, using a high enough dose of an atypical antipsychotic means that it actually becomes just as likely to cause TD as a typical one.
Note: One atypical antipsychotic, Clozapine, is notable for its extremely low rate of causing TD (it’s so low that it’s at the point that many researchers describe it as never causing TD). However, it has a potentially deadly side effect that requires getting regular blood tests as long as you take it. As such, it’s not frequently prescribed unless other antipsychotics aren’t working or someone already has TD and they’re trying to keep it from progressing.
Why are typical and atypical antipsychotics different?
The fancy psych answer is that typical antipsychotics have high affinity for dopamine D2 receptors, and atypical antipsychotics not only have a lower affinity to those receptors, but they also work on serotonin receptors.
WTF does that mean? Well, let’s go back to the roommate analogy!
A typical antipsychotic is like having a roommate that rarely leaves the house. It’s a lot easier to get overwhelmed by their messiness, because they’re constantly there creating it.
An atypical antipsychotic is like having a roommate that has a significant other and stays over at their place half of the time. It’s still possible to end up with a bad roommate, but because they’re not always around, it’s not as likely you’ll reach that point of no return.
What treatments are available?
CW: brief suicide mention
There is no cure for tardive dyskinesia once it develops. Taking someone off the antipsychotic quickly can prevent TD from getting worse, but that can result in a relapse of the symptoms that necessitated taking the antipsychotic in the first place. Your character may need to be switched to a different medication that has a lower rate of causing TD (see Clozapine above).
There are some ways to manage symptoms once they’ve developed:
Valbenazine is a brand-spanking-new drug that was only approved a few months ago! It’s really promising, and doesn’t seem to have that many side effects.
Tetrabenazine - this was traditionally used to treat TD, but it can have some serious side effects and can increase the risk of suicide.
There are other medications, but they seem to have mixed support as to their efficacy.
Also, interestingly, if someone has smaller, simple, more localized movements (think the cheek movements in #7 in the video), botox can actually be used to paralyze the affected muscle.
Why bother writing about this?
Well, it adds an element of realism to a character who’s taking antipsychotics. Even if you don’t want your character to develop tardive dyskinesia, it could be something your character worries about while taking the drugs, or even be given as a reason they don’t want to take them!
It’s the kind of detail that the Shrink never sees addressed in media, and I’ll automatically give bonus points to anything that includes a detail like this.
It must be hard for you going through a reality different from other people. It must be hard pointing something out that other people cannot see. It must be hard believing that your neighboor controls you or that your damn computer is trying to communicate you something or that your dead mum visits you at night before going to sleep or that your girl/boyfriend wants to poison you or that the goverment is after you and even if you understand somehow that it cant be real, you cannot believe otherwise.
It must be so hard and yet harder it is when people dont understand. Harder it is when people dont know what delusions and hallucinations are, telling that you are faking it, calling you a creep or a freak, ignoring you.
But I really hope that there are people close to you trying to understand your reality, trying to fight along with you every monster haunting your mind, holding your hand, shouting together with you to that shadow which always follows you to go away, making you believe that they love you even when your delusions show something different.
I really hope you are not getting the phrases: ‘it is not real’, ‘you are just imagining it’, ‘its only on your head’ because it must be FUCKING HARD to see something and to be told that its not there when your whole being feels it.
To each psychotic person: Know that you are unique and you can be stronger than you think. You are fighting the worst battles from us all: that with yourself, your mind, your and others perception, your and others reality and I am with you through all this. Please be strong.
Pet peeve: when someone has a bad experience with a psych med so they tell everyone else not to take it. Everyone reacts to meds differently, and just because you got the side effects doesn’t mean that person will. It’s just wrong to try to scare a person away from their treatment plan
Yo Sam! So i read in some article that antipsychotics might interfere with testosterone levels, but i couldnt find any proper or trans specific info on this. So im wondering if any of ur lovely followers has any experience with being on antipsychotics and t at the same time, and if so, could they contact me? Thank u!
I put on 30 pounds because of my second-generation antipsychotic.
These drugs are widely known to cause weight gain, cholesterol abnormalities, and metabolic problems including diabetes. If any of these things happened to you because of your antipsychotic, you are not a bad person. It doesn’t mean you’re lazy or didn’t have enough self control, it’s a very, very common side effect of the whole class of drugs.
i had a dream last night that was really fucking overwhelming and scary. it felt SO real and it went on for what felt like an entire real-world day. there was like really upsetting stuff going on and i woke up really fucking rattled
do… do antipsychotics do that to your sleep? or did i just have a shitty night?
I’ve been tried on a shit ton of meds so I figured I’d give my experience on them. My diagnoses are: schizophrenia, PTSD, generalized anxiety disorder, and borderline personality disorder.
Trazadone- WORST. SLEEP. MEDICATION. That I have EVER taken. Sent me into a psychotic break (thankfully I was inpatient at the time) and was overall a bad time. Made my psychosis horrible.
Vistaril- Same experience as Trazadone except a little less severe and made me a tiny bit less drowsy than trazadone did.
Remeron- It was most likely just my body, but I had a dystonic reaction to it and had hella leg jerks so I can’t take it.
Atarax- Was just like taking 50 mg of Benadryl. Made me drowsy but didn’t help my sleep at all.
Zoloft- This is the only antidepressant I’ve been prescribed for depression/anxiety and it really mainly helps my anxiety but at least it helps right? Dont cold turkey it if you don’t want to end up inpatient.
Abilify- Weight gain. Twitches. Sleep. One of the worst I was prescribed for my schizophrenia/psychosis. Even months after I’ve been off it I still have minor twitches in my neck/head area and put on 20 pounds I probably won’t lose. Helped my hallucinations the most but the side effects outweighed the benefits.
Risperdal: WEIGHT GAIN. Once again made me put on even more weight (about 10 pounds, so not as much as abilify). Made my brain foggy and I couldn’t concentrate on anything. Slightly toned down the voices, increased my paranoia.
Seroquel: Actual hell. I’m not bipolar but it ended me up in the hospital as my psychiatrist was worried it had made me severely manic. Constantly sleeping. Not much difference with psychotic symptoms.
Geodon: I wasn’t on this long, it just gave me severe anxiety. As for helping my symptoms, quieted voices a little bit, increased paranoia.
Latuda: made me VERY angry after only two days of being on it. Didn’t notice any difference in helping my psychosis.
Vraylar: This is what I’m currently on and have been on for about three weeks. It works almost as well as the abilify did as for psychotic symptoms but the twitches are worse than on the abilify. Still hearing and seeing things but not as severely. No weight gain so that is a plus!
Ativan- I’ve only ever taken Ativan as needed and it works wonders. Helps me sleep, calms me down, and helps the twitches from side effects of antipsychotics.
I hope this was helpful in some form in helping you chose and understand how meds might affect you!
hey okay so I got prescribed quetiapine and ofc, being the experienced pill popper I am, I always look up the side effects and I obviously found out abt the weight gain and I’m scared shitless. but my question is, to all of u taking it, does it increase ur appetite or do u just gain weight whatever u eat??
i’ve tried lyrica and I can see why weight gain is a side effect for them bc I got really hungry when I was on them so I’m wondering if it’s the same with quetiapine? bc that I can handle, but not if I’m gonna gain weight uncontrollably.
Please tell me ur experience it would really help me (:
Thank you for discussing being on antipsychotics and being trans. I’m transmasc and I’ve been on antipsychotics for bipolar since I was 16. It makes me feel better to know that I’m not alone. Question: are there any psych meds that you have to stop before or after a surgery?
Hi! You are definitely not alone <3
You can continue taking your antipsychotics in the week leading up to surgery, but the instructions for the night before and the morning of surgery depend on your particular surgeon.
My top surgeon said I had to stop eating and drinking at 8 pm the night before for my surgery which was scheduled at noon the next day, and advised me to take my nighttime dose of extended release antipsychotics at that point.
I can’t remember if I was told to take my morning dose of antipsychotics with a minimal amount of water on the day of surgery or if they wanted me to miss that dose and pick up with the nighttime dose, but at most I missed 1 dose on the day of surgery.
Surgeons may want you to stop doing certain things leading up to surgery, like smoking, but they tend to be okay taking psych meds. My surgeon said I should keep taking my meds in the week before surgery and right after surgery because recovering from surgery isn’t a good time to go off your meds and have to cope with all of that. They didn’t even want me to stop testosterone, which many surgeons ask you to do (even though there’s no evidence to support that it provides a benefit).
So as always, check with your surgeon, but I doubt they’ll tell you to wean off of psych meds.
1/2 I'm sorry for adding to your inbox but I really need to talk to someone about this. My new psychiatrist put me on atypical antipsychotics on top of my prozac because my depression was barely responding to my prozac, with it only taking away the suicidal symptoms. But I don't think I need them and I don't want to be on them. I can't explain why but the fact that I'm on them makes me feel awful and scared. I know some people need them and there's nothing wrong with that but I don't want them.
2/2 (antipsychotics anon) Plus the list of side effects scares me. And I think they’re starting to lose effectiveness after the first few months. This new psychiatrist also took me off of a medication I truly believe I need because he was afraid of side effects that I never experienced in the year I was taking them. I know it’s a lost cause with that medication but should I talk to him about the antipsychotics? I at least want to know why he thinks I need them.
You are always entitled to what your doctor’s reasoning is behind prescribing your drugs; if you feel this new psychiatrist isn’t acting in accordance with your best interests, let him know! Let him know that you think your prior medication was better suited to you inspite of the side-effects, and that your new medication is making you feel scared. Never assume that what you’re taking is necessarily what’s best for you!
While there’s a requirement to have a certain amount of trust in your medical professionals, never rule out getting a qualified Second Opinion if you feel you’re not being listened to or taken advantage of; no profession is exempt from incompetence, neglect or greed. There are good mechanics, and there are ones that will overcharge you and fill your car with garbage; they all have licenses too!
Use your own wiles as well; look up your drugs online to see how they interact — it’s always in your best interest to know things for yourself, especially when it applies to medication affecting your mind. Be smart, get secondary resources and medical opinions…
But that all comes after you tell your psychiatrist first that you don’t like your current meds; see what the response from him is before proceeding.
The only psychiatrist that I’ve been able to find in this damned country that specializes in dissociation and neurological disorders doesn’t even believe in DID. It did come up in the conversation, and he acknowledges that I have all of the symptoms, but he will only diagnose me with bipolar and borderline personality (Which I don’t disagree that I have), because it’s apparently not a real thing.
He made me feel so stupid when I tried to explain my alters to him and how they started presenting themselves to me and how they are not just voices but like actual people. That they take over my body sometimes and I forget what they do. They don’t just say random gibberish or insult me, I and other people on the outside can have fluid full conversations with them, etc. He just gave me an anti psychotic pretty much and told me to stfu and gtfo. Well, he was a little bit more professional than that but you get the idea.
I would be OK if a doctor told me I didn’t have DID/OSDD IF that doctor actually believed it was a real illness in the first place. Which I think would be really unlikely to happen because of the fact that I have all of the symptoms of DID/OSDD.
I asked him “what if I take this medicine and the voices don’t stop?” and he seemed so sure of himself that they were just psychotic delusions that would disappear with drugs.
Hopefully I can find someone more reasonable in this country, or maybe someone from america who can help me over skype…
The dark side of the second generation antipsychotic drugs: what the medical companies aren't telling you.
Estel is here with some disappointing news, folks. The British Journal of Psychiatry recently published an article about the efficacy of antipsychotic drugs. It has been discovered that many studies have found that the ‘new and improved’ second generation of antipsychotic drugs may not be so 'improved’ as they were hypothesized. It doesn’t end there though: drug companies have been enthusiastic in selling these antipsychotics as illusory advances in medical science without providing adequate information about potentially deteriorating side-effects of the drugs.
Unfortunately, this is a relatively new article and still under the folds. Hence, it is locked away from the likes of scientists and eager students alike for now. The good news is that it is set to be published during this month.
However, here is the last paragraph of the kick-ass editorial that managed to be released to the interwebs:
In creating successive new classes of antipsychotics over the years, the industry has helped develop a broader range of different drugs with different side-effect profiles and potencies, and possibly an increased chance of finding a drug to suit each of our patients. But the price of doing this has been considerable – in 2003 the cost of antipsychotics in the USA equalled the cost of paying all their psychiatrists.
The story of the atypicals and the SGAs ['second-generation antipsychotics’] is not the story of clinical discovery and progress; it is the story of fabricated classes, money and marketing. The study published today is a small but important piece of the jigsaw completing a picture that undermines any clinical or scientific confidence in these classes.
With the industry reputation damaged by evidence of selective publishing and its deleterious effects, and the recent claims that trials of at least one of the new atypicals have been knowingly ‘buried’, it will take a great deal for psychiatrists to be persuaded that the next new discovery of a drug or a class will be anything more than a cynical tactic to generate profit. In the meantime, perhaps we can drop the atypical, second-generation, brand new and very expensive labels: they are all just plain antipsychotics.
Anybody else feel that our health care system has become nothing more than a money-making business that preys on the vulnerabilities of individuals who are trying very hard to find constructive solutions to their illnesses? Faith can only be restored in health care if an individual feels that their health is a vital issue that needs proper care, attention and respect. In the wise words of Ms. Elizabeth Bennet: “the more I see of the world, the more am I dissatisfied with it; and every day confirms my belief of the inconsistency of all human characters, and of the little dependence that can be placed on the appearance of either merit or sense.”
Here’s to hoping that future health care workers, investors and business owners alike have got more than money on their mind.
Is anyone here on Risperidone for impulse control/mood stabilization? Would you mine briefly discussing it with me? I was prescribed it and I start taking it tonight to see how I respond to it. If I respond well in the next couple of days I start on celexa. Anyone mind discussing this with me????