Fenris, Dragon Age II
i think one of the best parts about being a teenager in the early to mid 2010s was that cigarettes were definitely not cool anymore and vapes hadn’t popularized yet so my lungs made it out of my peak impressionable years relatively unscathed
Oh here’s a pin wallpaper for y’all CAUSE I LOVE HIM
EDIT I NEED TO REMEMBER TO SIGN THINGS
THE FELLOWSHIP OF THE RING (2001)
happy october 24th!
someone looked at laudna wrong (inspired by this tweet)
some royal jewels were stolen from the louvre which is unfortunate for historical reasons but you gotta appreciate a classic crime. so many crimes are online these days it’s nice to see heist culture is still alive
i am massively overdue for a very very good week where not a single bad thing happens and everything is easy
reblog to give prev a very good week where not a single bad thing happens and everything is easy
thanks I hate it
You Got a Friend In Horse
YOU DO NOT HAVE A FRIEND IN HORSE
You Got A Lotta Friends In Horse
CANNOT STRESS ENOUGH THAT THOSE ARE NOT FRIENDS IN HORSE
*david attenborough voice* truly the most dangerous predator in the animal kingdom
are you guys hearing about this dude working to developing a vaccine for cats that he's hoping would like. theoretically double their lifespans?
turns out i wasn't making that up, his name is Dr. Toru Miyazaki! he also wrote a book called "The Day Cats Live To Be Thirty", so cats are kind of his thing.
apparently, cats' kidneys tend to be the thing that takes them down, something about their bodies being unable to self-clean their kidneys, and the vaccine is supposed revitalize the body's ability to do just that. It would be very VERY fucking cool to have cats suddenly reaching 30 years of age be the normal thing.
whoa wait i actually read the articles and it's so much cooler than just that!!
dude cracked the case about WHY kidneys fail, across the board as far as i can tell. turns out there's a specific molecule whose job it is to attach to waste and signal macrophages to come eat it. it remains inactive in cats for some reason, but the molecule is still there. basically what he's done is found the switch to activate them. this will be profound not only for our domestic babies, but for big cats too - especially cheetahs!
although his research was focused on cats, it's already being used to develop drugs for humans too!
on top of that, since these molecules are tags for waste, this could also dramatically lower the rate of fatty liver disease, liver cancer, urinary crystals, rheumatoid arthritis, and even some neurological cases! like, they're hoping it may have an impact on parkinson's and alzheimers, but it DOES have an impact on stroke recovery. like. holy shit.
furthermore, he's insisting that the feline drug be affordable if and when it rolls out onto the market. he wants this to be something anyone can get for their cat!! idk how much sway he'll have over the human drug, but hopefully enough that it, too, won't be that expensive.
annnnnd in his research that he's still doing for the human side of things, he's found a potential link between this molecule and estrogen. in the 20,000 samples he's tested, women between ages 10 and 29 had the highest amount of this molecule present in their blood (a higher amount means Something Fucky is going on, essentially. There's a higher amount of waste the body is trying to clean out) but it drops down to be almost equal amongst men and women after menopause. it hasn't been looked into yet, but fuck, just the fact it's noted and known and probably WILL be looked into soon??? imagine if this is what leads to figuring out all the various ways the ovaries and uterus fucks with people and how to fix it. or even like, maybe there's something about estrogen that makes it work better. who knows! but it's rad the link is there to be researched :D
man just think, not only could our kitties start living longer, healthier lives, but just maybe dialysis will become as rare and obsolete as the iron lung is for people. what a badass Dr. Toru is!
"But I don't want to turn people into dinosaurs. I wanna cure kittie kidneys!"
Absolutely horrid that a 10hr sleep does not cure you of all that ails you
it doesn't even cure me of being tired
















