yellow mouse

anonymous asked:

Hello there. Can you find me a sasusaku fanfic? with the storyline like Sakura getting sick, or nearly died so her husband begin worried? Sorry for my bad English, still learning.

A few, but not many! 

and that’s it! also, your english is very good! 

A friend and I stopped by the reptile store to pick up food for my snake and left with two pet rats.

While we were there we saw one of the feeder rats had no ears. Cute little mouse, only half grown, white with a black head known as a hooded rat. My friend took one look at her and asked if she could buy her as a pet. The shopkeeper was pleased because she was curious to see if the little girl would make it and was thinking of adopting her herself. She also said she’d like to find a home for “Cheerio” and pointed to little yellow mouse that was sharing the same drawer as the girl. 

Apparently there’s a guy who buys live food for his snake and names it when he buys it, and then returns it if the snake doesn’t eat it. He’d named this feeder “Cheerio” and returned him because his pet wasn’t hungry. So the shopkeeper felt bad for the rat, he’d been lucky to survive once and had a name now. In the end, she offered to give us the boy for free if we bought the girl. 

So now my friend has two pet rats, and two is a good number to have so they won’t get lonely. 

Supporting the damaged brain

A new study shows that embryonic nerve cells can functionally integrate into local neural networks when transplanted into damaged areas of the visual cortex of adult mice.

(Image caption: Neuronal transplants (blue) connect with host neurons (yellow) in the adult mouse brain in a highly specific manner, rebuilding neural networks lost upon injury. Credit: Sofia Grade, LMU/Helmholtz Zentrum München)

When it comes to recovering from insult, the adult human brain has very little ability to compensate for nerve-cell loss. Biomedical researchers and clinicians are therefore exploring the possibility of using transplanted nerve cells to replace neurons that have been irreparably damaged as a result of trauma or disease. Previous studies have suggested there is potential to remedy at least some of the clinical symptoms resulting from acquired brain disease through the transplantation of fetal nerve cells into damaged neuronal networks. However, it is not clear whether transplanted intact neurons can be sufficiently integrated to result in restored function of the lesioned network. Now researchers based at LMU Munich, the Max Planck Institute for Neurobiology in Martinsried and the Helmholtz Zentrum München have demonstrated that, in mice, transplanted embryonic nerve cells can indeed be incorporated into an existing network in such a way that they correctly carry out the tasks performed by the damaged cells originally found in that position. Such work is of importance in the potential treatment of all acquired brain disease including neurodegenerative illnesses such as Alzheimer‘s or Parkinson’s disease, as well as strokes and trauma, given each disease state leads to the large-scale, irreversible loss of nerve cells and the acquisition of a what is usually a lifelong neurological deficit for the affected person.

In the study published in Nature, researchers of the Ludwig Maximilians University Munich, the Max Planck Institute of Neurobiology, and the Helmholtz Zentrum München have specifically asked whether transplanted embryonic nerve cells can functionally integrate into the visual cortex of adult mice. “This region of the brain is ideal for such experiments,” says Magdalena Götz, joint leader of the study together with Mark Hübener. Hübener is a specialist in the structure and function of the mouse visual cortex in Professor Tobias Bonhoeffer’s Department (Synapses – Circuits – Plasticity) at the MPI for Neurobiology. As Hübener explains, “we know so much about the functions of the nerve cells in this region and the connections between them that we can readily assess whether the implanted nerve cells actually perform the tasks normally carried out by the network.” In their experiments, the team transplanted embryonic nerve cells from the cerebral cortex into lesioned areas of the visual cortex of adult mice. Over the course of the following weeks and months, they monitored the behavior of the implanted, immature neurons by means of two-photon microscopy to ascertain whether they differentiated into so-called pyramidal cells, a cell type normally found in the area of interest. “The very fact that the cells survived and continued to develop was very encouraging,” Hübener remarks. “But things got really exciting when we took a closer look at the electrical activity of the transplanted cells.” In their joint study, PhD student Susanne Falkner and Postdoc Sofia Grade were able to show that the new cells formed the synaptic connections that neurons in their position in the network would normally make, and that they responded to visual stimuli.

The team then went on to characterize, for the first time, the broader pattern of connections made by the transplanted neurons. Astonishingly, they found that pyramidal cells derived from the transplanted immature neurons formed functional connections with the appropriate nerve cells all over the brain. In other words, they received precisely the same inputs as their predecessors in the network. In addition, they were able to process that information and pass it on to the downstream neurons which had also differentiated in the correct manner. “These findings demonstrate that the implanted nerve cells have integrated with high precision into a neuronal network into which, under normal conditions, new nerve cells would never have been incorporated,” explains Götz, whose work at the Helmholtz Zentrum and at LMU focuses on finding ways to replace lost neurons in the central nervous system. The new study reveals that immature neurons are capable of correctly responding to differentiation signals in the adult mammalian brain and can close functional gaps in an existing neural network.




It’s the back end of spring break (meaning I’m home), so I decided to go through my old notebooks AND LOOKIE WHAT I FOUND. OH MY GOD. I GASPED ALOUD.

This little doodle was in the sketchbook I was using back when I was first into Warriors (I can tell from all the trying-to-figure-out-how-to-draw-cats doodles), meaning that this sketch is from 5th grade (which also happens to be when I had a certain dream that made Benny and Mumble even exist as actual characters). 5th grade for me was in 2008/09, btw.

So naturally I redrew it. Aaaand probably put an equivalent amount of work into both of them. xD