BLESSER 

[noun]

1. one who blesses; one who bestows or invokes a blessing. 

[verb] 

2. to wound; to injure. 

3. to injure oneself.

Etymology: from Middle French, from Old French blecier, “to injure, hurt”, from Frankish *blētjan, “to bruise”, from Proto-Germanic *blaitijaną, “to discolour, bruise”, from *blaitaz, “pale, discoloured”, from Proto-Indo-European *bhlAid- “pale, pallid”. Cognate with Old High German bleiza, bleizza, “livor, bruise”, Old English blāt, “pale, livid”.

[Huebucket - The Wound Man]

How a wound closes

For wounds to close, cells need to move collectively in one direction in a coordinated fashion. Until now the central molecular mechanism that allows cells to coordinate these movements over larger distances has been unclear. Now researchers from Heidelberg University and the Max Planck Institute for Intelligent Systems in Stuttgart have succeeded in decoding it. Collective cell migration is not only important in wound healing, but also in the development of the embryo and even of cancer. The results of their research, published in the journal “Nature Cell Biology,” have tremendous implications for all three of these areas.

Tamal Das, Kai Safferling, Sebastian Rausch, Niels Grabe, Heike Boehm, Joachim P. Spatz. A molecular mechanotransduction pathway regulates collective migration of epithelial cells. Nature Cell Biology, 2015; DOI: 10.1038/ncb3115

Epithelial cells move collectively out of their original shape (left) into the environment (right). Localisation of Merlin is shown in green, the cell nuclei in red. Credit: Max Planck Institute for Intelligent Systems

A Keen Ally

TITLE: A Keen Ally

CHAPTER NO./ONE SHOT: One Shot

AUTHOR: SierraLaufeyson13

ORIGINAL IMAGINE: Imagine being a part time Avenger and going into battle with Loki. Both of you work really well as a team, he’s the brains and your the brawn. You save him by stepping in front of a soldier and blocking their hit…

RATING: PG

NOTES/WARNINGS: So I had this written and then forgot all about it? Oh well, better late than never. 

“It’s called heterochromia iridum, Loki, and staring is rude.” Those were the first words you ever spoke to Loki, it was a chance meeting as he had been returned under the supervision of Thor to repent for his crimes and you had decided to finally show up at one of Stark’s parties. The god sat in the corner, away from the drunken antics of the guests, looking like he would rather be anywhere else than there. As the only empty seat on the edge of the room was by him, you took a seat next to time and slowly nursed the vodka tonic. There was no conversation and you could feel his eyes on you, it was unnerving. It was like any other person staring at your unusual appearance but it was the intensity of his scrutinizing glare that made you shift and speak out.

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Making a better wound dressing—with fish skin

With a low price tag and mild flavor, tilapia has become a staple dinnertime fish for many Americans. Now it could have another use: helping to heal our wounds. In the journal ACS Applied Materials & Interfaces, scientists have shown that a protein found in this fish can promote skin repair in rats without an immune reaction, suggesting possible future use for human patients.    

Jiao Sun, Xiumei Mo and colleagues explain that applying collagen—a major structural protein in animals—to wounds can help encourage skin to heal faster. But when the protein dressing comes from mammals such as cows and pigs, it has the potential to transmit conditions such as foot-and-mouth disease. Searching for an alternative source of collagen, scientists recently turned to the ocean. Sun’s team wanted to test fish collagen’s potential as a more benign wound treatment.

The researchers developed nanofibers from tilapia collagen and used them to cover skin wounds on rats. The rats with the nanofiber dressing healed faster than those without it. In addition, lab tests on cells suggested that the fish collagen was not likely to cause an immune reaction. The researchers conclude that it could be a good candidate to develop for clinical use.