(noun) An untranslatable German word, “consisting of Welt, meaning ‘world,’ and Schmerz, meaning 'pain.’ Just as your head can hurt (Kopfschmerzen), or you can suffer from a stomachache (Magenschmerzen), the world can hurt too.” In its mildest form, this is “world-weariness;” meaning sadness or melancholy at the evils of the world. “At the other extreme, it’s an existential pain that leaves you reeling with a damaging, head-clutching despair.”
- [literarily] world-pain.
-Moore, Christopher J.. In Other Words: A Language Lover’s Guide to the Most Intriguing Words Around the World (pg. 29).