Bacteria are incredibly small, yet pack an enormous diversity of
different molecules such as DNA, mRNA and proteins. Chemists from
Radboud University Nijmegen, Eindhoven and Paris now show for the first
time that random variations or ‘noise’ in cellular processes come to
exist because of an interplay between the rate of the reaction and its
environment. Nature Nanotechnology publishes the results on October 26.
Macromolecular crowding develops heterogeneous environments of gene expression in picoliter droplets
Maike M. K. Hansen, Lenny H. H. Meijer, Evan Spruijt, Roel J. M. Maas, Marta Ventosa Roquelles, Joost Groen, Hans A. Heus, Wilhelm T. S. Huck
Figure: In A, the droplets are situated in a non-viscous environment and in B they have a higher viscosity.