These are mostly people who were revived by a kiss or died on their god tier beds. As pointed out to me by theeldritchdreamer, that means that for the versions of them who died, there are no second chances. Their dream selves got to assume their memories and go on as the main version, but for the versions who died, it’s over.

EVEN IF SOMEBODY KISSES THEM.

EVEN IF THEY DIE, ON PURPOSE, TO BECOME GOD TIER.

Look at John’s face, he looks so confused and even frightened, because he was led to believe that he just needed to be brave and it would be okay. Dirk’s clever plan means nothing. All this time we thought death was nothing in the comic, but now Hussie turns around and lets us know that death always meant something, even when people thought they were silly for being afraid, when they found the courage to do what they thought was necessary anyway, no matter what.

Just take some time to contemplate and let that sink in.