ugh look at Bill's face LOOK

Myrna Loy first met William Powell on the set of the movie ‘Manhattan Melodrama’. Their first scene involved Loy’s character forcing her way into Powell’s cab. However, when shooting began and she landed on his lap, instead of saying his scripted line, Powell said “Miss Loy, I presume?” Both actors dissolved into a fit of laughter.

It was the first one of fourteen movies they shot together.