Brain Structure Differences Suggest Teens May Not ‘Grow Out of’ ADHD

Young adults diagnosed with attention deficit/hyperactivity disorder (ADHD) in adolescence show differences in brain structure and perform poorly in memory tests compared to their peers.

The research is in European Child Adolescent Psychiatry. (full open access)

Research: “Brain structural deficits and working memory fMRI dysfunction in young adults who were diagnosed with ADHD in adolescence” by Andres Roman-Urrestarazu, Päivi Lindholm, Irma Moilanen, Vesa Kiviniemi, Jouko Miettunen, Erika Jääskeläinen, Pirjo Mäki, Tuula Hurtig, Hanna Ebeling, Jennifer H. Barnett, Juha Nikkinen, John Suckling, Peter B. Jones, Juha Veijola, and Graham K. Murray in European Child Adolescent Psychiatry doi:10.1007/s00787-015-0755-8

Image: The poor memory scores seemed to relate to a lack of responsiveness in the activity of the caudate nucleus: in the controls, when the memory questions became more difficult, the caudate nucleus became more active, and this appeared to help the control group perform well; in the adolescent ADHD group, the caudate nucleus kept the same level of activity throughout the test. Credit: mararie.