this is what scientists do

I really do believe that at least part of the problem of people distrusting science has to do with how we as scientists portray ourselves.

We have actively created a system where we derive authority from being seen as better/smarter/more competent than everyone else and then when people ask why they should trust us we respond with a very condescending version of ‘because SCIENCE IS FACT’ or something along those lines.

Like, consider how that would feel from the outside? Here are a small group of people who you have never met/interacted with who sequester themselves in impenetrable ~elite institutions that you can’t access and don’t feel party to who then tell you that what they say is fact because they’re smarter and better educated than you. And if you ever try to question them (no matter how reasonable your objections may be/seem to you) they condescendingly pat you on the head and say something like ‘don’t worry we know better. you can’t possibly understand what we do.’

Why the hell would you trust them? 

No one likes being told that they’re not smart enough to understand something, and no one likes feeling excluded from something they’ve essentially been asked to accept sight unseen. 

I don’t really have a solution to this, except some vague notion about working harder to portray scientists as people working a job, rather than geniuses who are above it all. 

And like trying harder to understand where people are coming from when they question science. And remembering that being better educated than most doesn’t make us smarter than most. It just makes us better trained in certain types of thinking.

I just think we need to keep in mind what we are asking of people. Which is to put a whole hell of a lot of faith in us.

Nikola Tesla is the greatest b/c he loved pigeons and science and wanted to provide people with electricity at low cost but he was also lowkey trying to build a death beam. 

theatlantic.com
Thanks to Trump, Scientists Are Planning to Run For Office
And they’ve got help.
By Ed Yong

For American science, the next four years look to be challenging. The newly inaugurated President Trump, and many of his Cabinet picks, have repeatedly cast doubt upon the reality of human-made climate change, questioned the repeatedly proven safety of vaccines. Since the inauguration, the administration has already frozen grants and contracts by the Environmental Protection Agency and gagged researchers at the US Department of Agriculture. Many scientists are asking themselves: What can I do?

And the answer from a newly formed group called 314 Action is: Get elected.

Tying a knot can be tricky. Just ask any kid struggling with shoelaces. And scientists have it even harder when they try to make knots using tiny molecules.

Now, in the journal Science, a team of chemists says it has made a huge advance — manipulating molecules to create the tightest knot ever.

“Historically, knotting and weaving have led to all kinds of breakthrough technologies,” says David Leigh at the University of Manchester in the U.K., who notes that knots led to prehistoric innovations such as fishing nets and clothes. “Knots should be just as important at the molecular level, but we can’t exploit that until we learn how to make them, and that’s really what we’re beginning to do.”

Scientists Have Twisted Molecules Into The Tightest Knot Ever

Image: Stuart Jantzen/Biocinematics.com/Science

anonymous asked:

How about some sin? (͡° ͜ʖ ͡°) How about Reaper, Hanzo, Genji, and Roadhog getting tired of being teased by their needy s/o decides to pin their s/o down and over-stimulate the crap out of them

oh man oH MAN it’s been so long since i’ve written dirty shit g o o d b y e

Keep reading

Pajama Man, pt. 2

This was a Call of Cthulhu set in the ‘20s. The players are a lieutenant, a paranormal scientist, a priest, a politician, and a pro wrestler known only as Pajama Man. (I was Pajama Man.)

The smarter members of the group are investigating a journal inside a public library.

GM: Alright, so you’re all reading this journal when you hear a big commotion from the front of the library as staff members try to stop someone from entering the building.

Priest, OOC: What is it?

GM: It is a very large man in an old-timey bathing suit with four very large buckets of chicken in his arms, yelling to be allowed inside the library with his food.

Pajama Man, IC: Pajama Man will not relinquish his chicken to nerds!

(Cue a lot of laughing)

GM: What do you all do?

Scientist, Priest, Politician, OOC: Pretend we don’t know him.

Lieutenant, OOC: I get myself some chicken!

Study demonstrates role of gut bacteria in neurodegenerative diseases

Alzheimer’s disease (AD), Parkinson’s disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are all characterized by clumped, misfolded proteins and inflammation in the brain. In more than 90 percent of cases, physicians and scientists do not know what causes these processes to occur.

Robert P. Friedland, M.D., the Mason C. and Mary D. Rudd Endowed Chair and Professor of Neurology at the University of Louisville School of Medicine, and a team of researchers have discovered that these processes may be triggered by proteins made by our gut bacteria (the microbiota). Their research has revealed that exposure to bacterial proteins called amyloid that have structural similarity to brain proteins leads to an increase in clumping of the protein alpha-synuclein in the brain. Aggregates, or clumps, of misfolded alpha-synuclein and related amyloid proteins are seen in the brains of patients with the neurodegenerative diseases AD, PD and ALS.

Alpha-synuclein (AS) is a protein normally produced by neurons in the brain. In both PD and AD, alpha-synuclein is aggregated in a clumped form called amyloid, causing damage to neurons. Friedland has hypothesized that similarly clumped proteins produced by bacteria in the gut cause brain proteins to misfold via a mechanism called cross-seeding, leading to the deposition of aggregated brain proteins. He also proposed that amyloid proteins produced by the microbiota cause priming of immune cells in the gut, resulting in enhanced inflammation in the brain.

The research, which was supported by The Michael J. Fox Foundation, involved the administration of bacterial strains of E. coli that produce the bacterial amyloid protein curli to rats. Control animals were given identical bacteria that lacked the ability to make the bacterial amyloid protein. The rats fed the curli-producing organisms showed increased levels of AS in the intestines and the brain and increased cerebral AS aggregation, compared with rats who were exposed to E. coli that did not produce the bacterial amyloid protein. The curli-exposed rats also showed enhanced cerebral inflammation.

Similar findings were noted in a related experiment in which nematodes (Caenorhabditis elegans) that were fed curli-producing E. coli also showed increased levels of AS aggregates, compared with nematodes not exposed to the bacterial amyloid. A research group led by neuroscientist Shu G. Chen, Ph.D., of Case Western Reserve University, performed this collaborative study.

This new understanding of the potential role of gut bacteria in neurodegeneration could bring researchers closer to uncovering the factors responsible for initiating these diseases and ultimately developing preventive and therapeutic measures.

“These new studies in two different animals show that proteins made by bacteria harbored in the gut may be an initiating factor in the disease process of Alzheimer’s disease, Parkinson’s disease and ALS,” Friedland said. “This is important because most cases of these diseases are not caused by genes, and the gut is our most important environmental exposure. In addition, we have many potential therapeutic options to influence the bacterial populations in the nose, mouth and gut.”

Friedland is the corresponding author of the article, Exposure to the functional bacterial amyloid protein curli enhances alpha-synuclein aggregation in aged Fischer 344 rats and Caenorhabditis elegans, published online Oct. 6 in Scientific Reports, a journal of the Nature Publishing Group. UofL researchers involved in the publication in addition to Friedland include Vilius Stribinskis, Ph.D., Madhavi J. Rane, Ph.D., Donald Demuth, Ph.D., Evelyne Gozal, Ph.D., Andrew M. Roberts, Ph.D., Rekha Jagadapillai, Ruolan Liu, M.D., Ph.D., and Richard Kerber, Ph.D. Additional contributors on the publication include Eliezer Masliah, M.D., Ph.D. of the University of California San Diego.

This work supports recent studies indicating that the microbiota may have a role in disease processes in age-related brain degenerations. It is part of Friedland’s ongoing research on the relationship between the microbiota and age-related brain disorders, which involves collaborations with researchers in Ireland and Japan.

“We are pursuing studies in humans and animals to further evaluate the mechanisms of the effects we have observed and are exploring the potential for the development of preventive and therapeutic strategies,” Friedland said.

3

“Thats it - poof - its gone!” You barked, throwing your hands in the air as you paced back and forth, growling individually at the three of them, causing Barry and Cisco to cower beneath your ire whereas Harrison stood quietly with his arms folded over his chest, wisely nodding in all the right places as you continued scolding them. “I thought you knuckleheads said you were scientists… Scientists. Technology is what you do! I’ve seen you three do incredible things and the very second you try to pull data off my hard drive, you end up wiping the entire thing clean… How do you screw up with something like that?!”

“I uh…” Barry began sheepishly before clearing his throat. “I’m technically in forensics so… Like, that’s still science I guess, but-”

Quickly shushing him, you pitched over your computer and bit your lip, thinking very hard about how you were going to recover your lost data… “I just… Hang on. I just need some peace and quiet if I’m going to figure this out.”

“Right.” Barry said. “I’ll just… I’ll be quiet.”

“I’ll be peace…” Cisco’s blurted before bumping Barry with his elbow.

Looking up, you found him sniggering and making a V-shape gesture with hand; his middle and pointer fingers scissoring a bit and completely sending you over the edge. 

“Allen.” Harrison’s voice broke through the tension. Clearly noticing how you were debating on whether or not to jump over the desk and rip their jugulars out, he probably felt now was a good time to intervene. Casting them a side-glance that teetered back and forth between humorous and sympathetic, he growled, “Shut him up.”

(X) (~♫♪~)

Request: Imagine the men on team flash doing something stupid and the reader just blowing up at them like all mad and cisco and barry are scared and harry is just smirking like whut? But like sh’es really mad.

“A List from the PunMaster”

For those of you who follow the blog closely, you’ll know that one or two tricksters have been flooding our inbox with puns for the past couple of weeks. When we brought it up in a post (click here), we got many responses asking for us to post every pun we received. So, here we are, and here are the numerous puns:

  • What does a Japanese dog say to greet another? Konichihuahua
  • Rest in peace, boiled water. You will be mist.
  • When chemicals die, do scientists barium?
  • What does a thesaurus eat for breakfast? A synonym roll.
  • Gaston is the winner of the No Belle prize
  • Just remember: if you ever get cold, stand in the corner because they’re around 90°.
  • What do you call a pig’s special karate move? A pork chop.
  • Cinderella was cut from the team because she was always running from the ball.
  • What starts and ends with “e” but only has one letter?
  • Does your town play the Lottery? I hope not. I wouldn’t want you to get stoned if you won.
  • The king looked outside his window and stared up at the darkening sky, lips slightly turned up. A servant came into his room to help the king prepare for the day and inquired as to how he was fairing. The king’s response was neither one of feeling well or otherwise, only a simple, “It shall be another reign-y day.”
  • What do you call a lazy joey? A pouch potato.
  • To be honest, sometimes I wish that Harry had named Hedwig “Hoodini” instead. Then they’d both be magical. And hoo knows, maybe Hedwig could have escaped death, too. [I apologize for that last part]
  • You’re flooded? Sorry, but I can’t really help that I’m dripping with good puns.
  • Sorry if I do any bad chemistry jokes. All the good ones Argon.
  • I kind of feel bad for all the Christian Bale “Batman” fans, the newer actor really seems to be Affleckting them.
  • If Nixon had been an animal, he most likely would have been a crookodile
  • Do you know what the real Instagram is? Putting your grandmother on speed-dial.
  • Hey, if the past, present, and future all walked into the same bar, don’t you think it would be really tense?
  • What was Socrates’ favorite thing to mold? Play-Doh
  • Do you think writers ever get cold? After all, they are surrounded by drafts.
  • What’s the best way to get an English major in the mood? Metaphor play.
  • When he was younger, my brother wanted to be an astronaut, but to be honest, he’s only reached the first syllable.
  • Hey, is your left eye okay??? Because you’ve been looking just right all day.
  • What’s the difference between calculators for middle and high school math? 5318008 vs I WANT TO DIE
  • Ren: Jaune, put the scissors down.
  • Jaune: No, I know what I'm doing! I'm a fucking scientist! Now watch as I use this pair of scissors to diffuse this bomb!
  • (An amount of hours later)
  • Ren: ...
  • Nora: ...
  • Ruby: ...
  • Jaune: ... We gonna talk about what just happened?
  • Ren: ... You somehow diffused a chemical time bomb with nothing but a pair of children's safety scissors.
  • Jaune: ... And how?
  • Ruby: (sighs) because you're a fucking scientist.
  • Jaune: Damn skippy, never get it twisted.
3

Not wanting to go all ‘Private Hudson’ here but we’re seriously doomed, aren’t we?

I love Marvel. The Unstoppable Wasp is a direct attempt to get girls interested in science. It brings up the work of several female Marvel characters that get glossed over most of the time. Like Dazzler's singing and Mockingbird's career as a scientist. The back page has an interview with two REAL LIFE lady scientists about what they do and why it's interesting or fun. 💖🔭🔬 I love science from watching women like Dr. Dana Scully as a child. It's so neat to see that inspiration spread into comics.