A teratogen is any agent—chemicals, viruses, environmental agents, physical factors, and drugs—that acts during embryonic or fetal development to produce a permanent alteration of form or function. The word teratogen is derived from the Greek teratos, meaning monster. A hadegen—after Hades, the god who possessed a helmet conferring invisibility—is an agent that interferes with normal maturation and function of an organ. A trophogen is an agent that alters growth. Hadegens and trophogens generally affect processes occurring after organogenesis or even after birth. Chemical or physical exposures that act as hadegens or trophogens are much harder to document. For simplification, most authors use the word teratogen to refer to all three types of agents.

Williams’ Obstetrics 

(gotta love etymology)

Just a few cm3 of diazomethane solution in ether before using it in a reaction. Diazomethane is the most simple diazo compound and was discovered by Hans von Pechmann in 1894.

At us the diazomethane is generated in ether from the highly toxic, carcinogen, mutagen, and teratogen N-Nitroso-N-methylurea (NMU) (since it’s cheap and it is easy to make it even on large scale: http://labphoto.tumblr.com/post/37655887344/just-made-some-n-nitroso-n-methylurea-the-direct ) with a concentrated solution of potassium hydroxide, than dried on solid potassium hydroxide. 

A few things to note: it should not heat up, since it could explode.

It should not contact any ground glass, since it could explode.

It should not be stirred with stirring bar, since it could explode.

Any source of fire close to the solution may led to an explosion.

It has also weird smell, and can gives you a nasty pneumonia + lung edema if you breath it.

By the way, it’s a really great reagent, it react well in most cases and it’s easy to work with it.

With Hamas vs. ISIS in Gaza, Israelis feel caught in the middle
Each siren and explosion reduces the hopes that this year’s summer vacation will be very different from last year.

In reality, the Palestinians are the ones caught in the middle of ISIS and Israel. Let’s review:

Last summer one terror state, Israel, massacres 1400 Palestinian civilians in Gaza, then this summer another terror state, ISIS, threatens to do in Gaza what it did in Yarmouk. But let’s all cry about summer vacation in Israel?