I just realised....
Molly slapped Sherlock. Hard. Three times. Because he was high
John slapped Sherlock, then punched him, then kicked him repeatedly. Because he was high
When Sherlock came back from the dead, John tackled him, hit him, and headbutted him.
Lestrade is the only one who reacted with delight and warmth and embraced him into a hug.
And Lestrade is probably the only one who offers a helping hand and tries to sober him up he first saw Sherlock drugged up and high off his tits
At this point, Lestrade is the only friend I can trust to protect Sherlock