shiley

More #HalfGodHalfDevil Tour dates have just been announced. See you on the second leg this summer with @inthismomentofficial, @vimicmusic and @littlemissnasty. Tickets go on-sale Friday at motionlessinwhite.net
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6.28 - The Pageant - St. Louis, MO
7.01 - House of Blues - North Myrtle Beach, SC
7.02 - Norva - Norfolk, VA
7.05 - State Theatre Portland - Portland, ME
7.07 - Asbury Park Convention Hall - Asbury Park, NJ
7.11 - Coronado Performing Arts Center - Rockford, IL
7.12 - McGrath Amphitheater - Cedar Rapids, IA
7.15 - Shiley Acres - Inwood, WV
7.21 - Concrete Street Amph. - Corpus Christi, TX
7.22 - South Side Ballroom - Dallas, TX
7.23 - La Hacienda Event Center - Midland, TX
7.25 - The Cotillion - Wichita, KS
7.26 - 7 Flags Event Center - Clive, IA
7.28 - Orpheum Theater - Madison, WI
7.29 - Mayo Civic Center - Rochester, MN
7.30 - Fargo Civic Auditorium - Fargo, ND
8.01 - Bismarck Event Center - Bismarck, ND
8.03 - Shrine Auditorium - Billings, MT
8.04 - Ironhorse Saloon - Sturgis, SD
8.05 - Downtown Lincoln - Lincoln, NE

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Hey, hey! I’ll be at SDCC 2016 this weekend! If you’re going, please drop by and say hi! :D

FRIDAY, JULY 22:

SIGNING
11:00am-12:00pm
Autographing Area 21
I’ll be there with the amazing Raina Telgemeier! I’ll have previews/copies of my upcoming graphic novel NEWSPRINTS with me, and maybe some SAINT FOR RENT miniprints, if you ask. ;)

YOU CAN BE THE NEXT SCHOLASTIC GRAPHIX ARTIST 
12:30pm-1:30pm 
Convention Center, Room: 24ABC
Find out how to get published by Scholastic, the #1 graphic novel publisher for children! What does it take to be published by Scholastic’s Graphix imprint? Stay tuned for a special announcement!
(I’ll be there with Scholastic creators Raina and Jeff Smith, and our editors!)

HOW COMICS GET CREATED
2:00pm-3:00pm 
Shiley Special Events Suite, San Diego Central Public Library
How do comics get made? If you have a library comics club or any aspiring young creators, it’s useful to have an understanding of the comics creative process to help them on your way! In this program, authors explain their process, demystifying comics creation for librarians.

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SUNDAY, JULY 24

CREATING DIVERSE WORLDS AND CULTURES
12:00pm-1:00pm
Convention Center, Room 28DE
A lot of science fiction fantasy takes place in worlds inspired by Western and European cultures. How can writers break that trend and create fully-developed, unique cultures for their stories?

SIGNING
2:00pm-3:00pm
Autographing Area 09

<3!!

Stem cells regenerate human lens after cataract surgery, restoring vision

Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses.

The treatment, which has been tested in animals and in a small, human clinical trial, produced much fewer surgical complications than the current standard-of-care and resulted in regenerated lenses with superior visual function in all 12 of the pediatric cataract patients who received the new surgery.

The findings are published in the March 9 online issue of Nature.

Congenital cataracts – lens clouding that occurs at birth or shortly thereafter – is a significant cause of blindness in children. The clouded lens obstructs the passage of light to the retina and visual information to the brain, resulting in significant visual impairment. Current treatment is limited by the age of the patient and related complications. Most pediatric patients require corrective eyewear after cataract surgery.

“An ultimate goal of stem cell research is to turn on the regenerative potential of one’s own stem cells for tissue and organ repair and disease therapy,” said Kang Zhang, MD, PhD, chief of Ophthalmic Genetics, founding director of the Institute for Genomic Medicine and co-director of Biomaterials and Tissue Engineering at the Institute of Engineering in Medicine, both at UC San Diego School of Medicine.

In the new research, Zhang and colleagues relied upon the regenerative potential of endogenous stem cells. Unlike other stem cell approaches that involve creating stem cells in the lab and introducing them back into the patient, with potential hurdles like pathogen transmission and immune rejection, endogenous stem cells are stem cells already naturally in place at the site of the injury or problem. In the case of the human eye, lens epithelial stem cells or LECs generate replacement lens cells throughout a person’s life, though production declines with age.

Current cataract surgeries largely remove LECs within the lens; the lingering cells generate disorganized regrowth in infants and no useful vision. After confirming the regenerative potential of LECs in animal models, the researchers developed a novel minimally invasive surgery method that preserves the integrity of the lens capsule – a membrane that helps give the lens its required shape to function – and a way to stimulate LECs to grow and form a new lens with vision.

In subsequent tests in animals with cataracts and in a small human trial, they found the new surgical technique allowed pre-existing LECs to regenerate functional lenses. In particular, the human trial involved 12 infants under the age of 2 treated with the new method and 25 similar infants receiving current standard surgical care. The latter control group experienced a higher incidence of post-surgery inflammation, early-onset ocular hypertension and increased lens clouding.

The scientists reported fewer complications and faster healing among the 12 infants who underwent the new procedure and, after three months, a clear, regenerated biconvex lens in all of the patients’ eyes.

“The success of this work represents a new approach in how new human tissue or organ can be regenerated and human disease can be treated, and may have a broad impact on regenerative therapies by harnessing the regenerative power of our own body,” said Zhang, who also has an appointment at Veterans Affairs San Diego Healthcare System.

Zhang said he and colleagues are now looking to expand their work to treating age-related cataracts. Age-related cataracts is the leading cause of blindness in the world. More than 20 million Americans suffer from cataracts, and more than 4 million surgeries are performed annually to replace the clouded lens with an artificial plastic version, called an intraocular lens.

Despite technical advances, a large portion of patients undergoing surgery are left with suboptimal vision post-surgery and are dependent upon corrective eyewear for driving a car and/or reading a book. “We believe that our new approach will result in a paradigm shift in cataract surgery and may offer patients a safer and better treatment option in the future.”

Shiley || Disneyland Date

It was Valentine’s Day, and Shane wanted to take Riley out, but he also didn’t want to leave Isabella home with his parents. So he decided to go with his parents and Riley so that way it was a family day but they could go on some rides together cause his parents could watch the baby. It was going to also be Cameron, Mackenzie & Zoey because they were being taken care of by his parents while Nate & Elena were away.

It was 9 AM and Shane woke up early to take care of Isabella. She was 2 months old and he was having the time of his life taking care of her while he worked on his new album. He got her dressed and ready for the day and smiled as he carried her into the bedroom. He sat down on the bed and put her on his lip and shook Riley softly. “Babe someone kinda needs your boobs and it’s not me.”