This scene is pretty amazing. We know that a huge part of Misato’s inner turmoil is that she cannot face against her father’s killers head on – instead, she must exact her revenge on the Angels vicariously through Shinji, Asuka, and Rei. But in this one moment, framed in such a way that disturbs our sense of magnitude, Misato is forced into lethal proximity with what she hates the most and stares it down anyway. She doesn’t run like the others. Notice that grip on her cross – subconsciously protecting her father’s memory, his only essence, over her own life.
In the tradition of ars moriendi, to die a good death is to die as you’ve lived: face death with resolution and maintain your deeply held convictions till the end.
Shinji comes swooping in to fend off The End at the very last second, but it’s a good reminder that for Misato, killing Angels isn’t about saving lives or protecting the world - it’s personal. Not so noble – Evangelion being the kind of show that it is – but it is compelling.