pilocytic astrocytoma

rongasm  asked:

-sigh- Okay. I am weak. I am weak, weak, weak, but I need an AU in which Percy and Annabeth are both doctors in the same hospital, maybe residents or attending physicians. Annabeth's in one of the more competitive specialties, like neuro or cardio, and Percy's in peds. *punches self in the soul because it would hurt less than how cute that would be*

  • at 30 years old, Annabeth was set to be one of the best neurosurgeons in the country (though she had her sights on the world) 
  • in the 4th year of her residency she felt like she had the hospital figured out
  • she knew the best places to take your brakes, who the best nurses were and was familiar with the usual crop of volunteers 
  • her best friend Piper was a cardiologist and her good friend Hazel was a nurse in the pediatrics department 
  • once a week the three of them would meet on the 10th floor patio for lunch, sharing the best hospital gossip 
  • “Hazel have you met the hot new doctor in pediatrics I heard about?” Piper said, wiggling her eye brows 
  • “I haven’t! He’s been pretty low key though, I don’t think many people have met him actually.” 
  • “Well Annabeth you should definitely call dibs on him since you haven’t gotten laid in forever” 
  • “It has not been forever since I’ve gotten laid! And I’m not gonna call dibs on someone I’ve never seen.” 
  • “I have a good feeling about this one,” Piper said with a smirk. “Trust me, Annabeth. They don’t call me the Queen of Hearts for nothing.” 
  • “They call you the Queen of Hearts cause the cardiology department is made up of nerds who all want to sleep with you.” 
  • “You say that like it’s a bad thing.” 
  • they all took separate routes from their lunch spot back to their respective stations and Annabeth’s happened to pass right by the play room 
  • when she saw him, she thought he was a volunteer 
  • he was wearing a simple blue t-shirt, jeans, and black vans and was on the floor at the bottom of a dog pile of kids 
  • he looked up just as Annabeth passed by and gave her a lopsided grin
  • Annabeth almost took out a nurse, she was so distracted 
  • she went on about her day, but her mind always seemed to drift back to those eyes 
  • the next day Annabeth was told to meet Chiron, the attending physician who she usually shadowed, in the pediatrics wing to get some experience with a younger patient 
  • when she walked in, the volunteer from the day before was sitting on the edge of the patient’s bed making funny faces and making the kid laugh 
  • “Is this guy harassing you?” Annabeth asked the little girl with a wink 
  • “You must be Dr. Chase. Chiron told me he asked you to stop by.” 
  • “And you are?” 
  • “Oh right,” he said, getting up from the bed and grabbing his lab coat from the nearby chair 
  • he took his stethoscope out of his pocket and slung it around his neck, “I always forget to put these back on after play time” he stuck his hand out to shake hers, “Percy Jackson’s the name, helping sick kids is my game” 
  • Annabeth took his hand and considered him, “Nice to meet you, Dr. Jackson” 
  • he introduced her to Lavender, the patient they were in the presence of who was suffering from a Juvenile pilocytic astrocytoma
  • “that means I have a tumor on my brain that makes me get dizzy sometimes!” the ten year old chimed in 
  • Annabeth would be assisting Chiron with the removal of the tumor and Percy would tend to Lavender before and after the surgery 
  • after the meeting and saying bye to Lavender, Percy offered to walk Annabeth to the elevator which she gladly accepted 
  • “I’m glad I finally got to meet the hot new pediatrician everyone keeps raving about.” 
  • “Well I’m honored that the most promising neurosurgeon in her program thinks I’m hot” 
  • they are saved by the elevator ding and Annabeth gets on 
  • as the door closes, the corners of her mouth rise into a smirk, “See you around, Dr. Jackson.” 

Hello, my favorite brainy people of the internet!
We’ll be talking about some brain tumors today.
All of the mnemonics might not work for you, so take only what you need :)

Glioblastoma Multiforme:
It is the most common malignant CNS tumor in adults. It has a butterfly appearance as it commonly crosses the corpus callosum. Areas of necrosis and hemorrhage are present. (This was asked as a MCQ in my exam!) GFAP positive.

Glioblastoma Multiforme mnemonic:
GlioBUTTERFLYoma multiforme.
G for Glioblastoma, G for GFAP.
G for gangrene (Lame way to remember about the hemorrhage and necrosis!)

A whorled appearance is seen, histopathologically. It commonly presents in women and expresses estrogen receptors. It can calcify resulting in psammoma bodies.

Meningioma mnemonic:
M flipped upside down looks like a W for whorled, women.

Psammoma body mnemonic:
Papillary carcinoma of the thyroid
Papillary renal cell carcinoma
Serous cystadenocarcinoma of the ovary

Fired egg appearance or chicken wire capillary pattern seen on histology. It commonly involves the white matter of frontal lobe resulting in seizures.

Oligodendroglioma mnemonic:
Eggs look like O.. OligOdendrOgliOma. Fried eggs leads to a fried brain. Fried brains cause seizures.

Pilocytic astrocytoma:
It’s a benign tumor of astrocytes, most common tumor in children. It involves the cerebellum (below the tentorium). Rosenthal fibers are eosinophilic, corkscrew fibers found in pilocytic astrocytoma. Pilocytic astrocytomas generally form sacs of fluid (cysts).

Pilocytic astrocytoma mnemonic:
PiloCYSTIC astrocytoma.
AstROSEcyte. ROSEnthal fibres!

Often localized to CN VIII, found in cerebellopontine angle, S-100 postitive. Histologically, shows cellular Antoni A area and paucicellular Antoni B area.

Schwannoma mnemonic:
For Schwannomas I remember the bird, “SWAN”
S-100 positive
Well circumscribed
Acoustic Schwannomas are common (More common than Trigeminal Schwannomas!)
ANtoni A and ANtoni B
Neurofibromatosis type 2 has bilateral Schwannomas.

Pituitary adenoma:
It’s a prolactinoma, most often. Derived from Rathke’s pouch. Can cause bitemporal hemianopia.

Pituitary adenoma mnemonic:
P for Prolactinoma!

Is a benign childhood tumor, derived from remnants of Rathke’s pouch. It is the most common childhood supratentorial tumor (Infratentorial is pilocytic astrocytoma, remember?) Tooth enamel like calcification is seen. Can cause bitemporal hemianopia.

Craniopharyngioma mnemonic:
C for Children, Calcification.
R for Rathkes pouch!

Ependymal cell tumors most commonly found in 4th ventricle and thus can cause hydrocephalus. Characteristic perivascular pseudorosettes seen on histology. Rod-shaped blepharoplasts (basal ciliary bodies) found near nucleus.

Ependymoma mnemonic:
Epic Ependymoma. (Sounds similar, yaay!)
E for ependymal cells.
P for pseudorosettes.
I for inside the cavities of the brain (How I remember involvement of the ventricles!)
C for ciliary bodies.

Most often cerebellar, associated with von Hippel-Lindau syndrome, can produce erythropoeitin causing secondary polycythemia.

Hemangioblastoma mnemonic:
HEmangioblastoma! H for Hippel. E for EPO.

That’s all!

This post was requested by Kay =)
I covered most of them for you, lemme know which else do you need!