organ rejection

Scientists with Disabilities

Okay so, this is all research for an essay I’m doing in school.

So we all know about Stephen Hawking. Worlds smartest man, has ALS, wheelchair bound, uses a text-to-speech software to talk, yeah??

Well what about the fact that a bout of scarlet fever left Thomas Edison almost completely deaf in both ears?

Or Leonardo Da Vinci was mist likely dyslexic, as most of his notes were in reverse?

Albert Einstein didn’t talk till age 4 and was most definitely Dyslexic.

John Forbes Nash, Jr was schizophrenic, and required hospitalization multiple times. He also revolutionized the Business world with the “Nash Equilibrium”.

Temple Grandin is a female Animal Behaviourist, who has her Ph.D and helped revolutionize the livestock industry. She’s Autistic.

Geerat Vermeij is a paleontologist whose research helped others understand how fossils interact with the world at large. He’s been diagnosed with Glaucoma and bee blind since age three.

Edwin Kerbs (Nobel Prize Winner) is a biologist from the 50’s who made a discovery about cellular activity in the human body that helped understand hormones, cell life spans, and how bodies reject transplanted organs. He was hearing impaired, and was one of the last people to find our he had won the award as he didn’t hear the phone ring.

Farida Bedwei is a South African software engineer who has been heralded as one of the most important figures in financial tech. She was also diagnosed with Cerebral Palsy at age one. A black, female, disabled scientist who is at the forefront of her field. She’s amazing.

This is awesome!! look at all these cool people!! thank you!!
Letter of Resignation

Dear Maya,

This is an official resignation from the position of personal responsibility to uphold your assets. It has been a wonderful decade with lots of growth and realization. The experience I’ve gained in this position will help me in all future endeavours. However, it has also taken a toll on my physical and mental wellbeing.

While I see the value in your social, cultural, political, economic, and moral constructs I just don’t see myself upholding their importance in my mind for the rest of my short stay in this meat suit. In the ten years I have spent at your organization I have watched myself deteriorate from a happy and free being into something filled to the brim with anxiety and depression.

I don’t want you to take this the wrong way, while I resign from the position of responsibly I am in no way protesting or rejecting your organization. I will still happily partake in your events and celebrations, but as a visitor rather than a stakeholder. As promised I will still deliver your architecture department my grand vision, as was the original intent in my taking of the position in the organization ten years ago.

Unfortunately I had lost track of this reason at least five years ago. This resignation will allow me, I feel, to have a much more beneficial effect on both my own endeavours and on your org as well. I’m sure a company your size will have no problems filling my share of responsibility–I’ve been slacking off anyways.

Thank you for the opportunities in the time we’ve spent together, feel free to call or write.

Pash
T: 0-111-666-2270
E: had@nu.lol

  • What she says: I'm fine
  • What she means: I'm really not fine with the fact that some people think snape was actually a good person because he tried to make up for his mistakes by protecting an orphan that lost his parents BECAUSE OF HIM. Also he fucking abused his students, even the one he was supposed to FUCKING PROTECT remember???, called the only friend he had a mudblood, joined a racist organization because he was rejected by some chick, created his own spell to slice people in half and make sushi out of them, told the dark lord about a profecy and only regretted it because it was interpreted to be about the woman that he had loved but friendzoned him because he was a racist bastard and

anonymous asked:

Interesting how liberals would NEVER support Westboro Baptist Church who (to the best of my knowledge) have never killed anyone. But Islam they'd defend until they're blue in the face? Am I missing something or...?

You aren’t missing much. I would only like to say that Westboro is not Baptist or Christian. They are a small handful of nuts that are using the “church” designation as a tax dodge more than anything. So I would not support Westboro either and all Christian organizations out there have rejected Westboro’s bizarre ideology as it is not Christian. But I definitely get your point. 

I don’t know if anyone’s had ever addressed this or not, but Helen Cho and her people printer, why isn’t this talked about more??

Like I come back to the people printer a shit ton when I’m sitting around doing nothing. I’m no scientist or biologist or any type of doctor, I’m just an art school drop out trying to wrap my little brain around that people printer thing.

Like Bruce specifically says “She (Cho) is creating tissue!”, and after Clint jokes that he is going to be made of plastic Cho reassures him that he is “Going to be made of you (Clint).” So in my little unprofessional mind this says that Cho has figured out a way to rapidly clone and replicate cells and join them with the preexisting cells with no problems and little recovery time. Recovery time after a skin graft is about two to three weeks depending and the area must be kept safe from any sort of trauma (hit, scratch, stretch), yet we clearly see Clint up and moving and even fighting in like two days.

FUCKING AMAZING

Oh and then she pretty much creates a sentient being, which is kinda a fluke and something she couldn’t really do again, because like Vibranium cost the big bucks and there is only one Mind Stone…. So i would assume only one Vision. But she STILL created artificial life, so the question still remains, what else can she do with that thing?

So like if it is indeed cloning cells, she could probably print organs. Like there would probably be little fear of the body actually rejecting the organ because, hey guess what?! It’s the persons actual organ. And is the printer precise enough to say actually print a replacement limb? Like could it clone the bone and tissue and each little vein and part of the nervous system so that it would actually be compatible with the persons already existing nervous system? Would fine motor skills still be present? Or what about touch as a sensation? Could it get precise enough to print an eye? Like pupil, cornea, rods, and cones that actually work? And can send that info to the brain in tandem with the other eye? Or what about organs that didn’t work properly in the first place? Can it mend or replace those?

Could this thing also be applied to cosmetic surgery, both voluntary and involuntary? Like in the case of burn victims and skin grafting, could it also clone and recreate the ruined and missing tissue? Or say if someone wanted breast enlargement, could it print more cells for a bigger bust? Or remove tissue and prevent scars? Or what about gender reassignment surgery? Could it be used for something as benign as tattoo removal? Or scar removal? Can it reconstruct a face?

Like I need to know the extent of Helen Cho’s people printer, and if half of this shit is even remotely possible that woman needs like 10000x more recognition and like her own movie or show. Because I would watch a medical drama where Cho fixes damn near everything with her trusty people printer!

When I tell people I am raising my own livestock for food, they freak out and act like I just murdered their cat. Believe me, my co-workers think I am a monster. I feel better knowing where my meat came from and how it was raised–I also have a damn good reason for that.

Most of you may have heard I’ve been very sick this past year with GI problems. My GI doctor never actually found out why I was so sick all the time. I decided to see another specialist. After many tests, he finally told me what was wrong. My colon is infected and has failed to work properly with my other organs. Why? Because a large portion of meats nowadays carry antibiotics. To some people, maybe that doesn’t sound bad. But to me, it is really bad. It’s actually uncommon for somebody’s organs to reject the antibiotics in meats that are ingested. I just so happen to be that unlucky person.

So before you judge me for raising my own food, maybe you should understand WHY I do it. And no, being a vegan does not sound appealing to me.

anonymous asked:

You're a communist right? I don't know if you've done this before but could you just explain why you think communism is better than anarchism?

Communism is a classless, stateless society predicated on de facto post-scarcity and “from each according to their ability, to each according to their need”. Anarchism is a classless, stateless society predicated on free association and the abolition of the wage system. They’re effectively the same thing. People who call themselves communists (rather than anarchist or anarcho-communist) are also typically Marxists, and they in turn likely believe that a transitory socialist system will be a necessary stage before viable communism/anarchism. Anarchists want to abolish capitalism and the state in one fell swoop. I never explicitly said I was an anarchist (Greg is, however), but rather a libertarian Marxist or Luxemburgist. I find myself leaning towards believing in the necessity of some transition period, but I think the state in that scenario should be heavily tempered by worker councils and democratic organizations. I reject the notion that the state should undemocratically assume control of the means of production, and I fully support anarchist efforts otherwise. I think the issue will fundamentally be determined by the conditions, popular support, and resource access when the day of revolution comes.

Grafting Half-Ghouls

I’m not sure how useful this will be considering humans aren’t plants, but I’m a bit of a plant nerd, so when I read Kanou talking about grafting, I couldn’t help getting excited and looking into some stuff.

To preface this, I’m not claiming to be a botanist, nor a passionate hobbyist or horticulturist. I participated years ago in a high-school-level national competition for Floriculture and had to study some of this floriculture/horticulture plant propagation stuff… meaning I’m rusty and not all that qualified. Most of this post is an amalgamation of old notes, brushing up on terms through Wikipedia, and combing through a dozen grafting community pages and university articles. So take this with a grain of salt.

Again, humans are not plants, so there’s bound to be a bunch of differences to how the body actually works with an organ from another species (I’m leaving that talk to people more qualified in biology/genetics/anatomy/medicine), but if you want to take the situation as a metaphor, grafting works quite well.

Saying all that, let’s begin! (Super long post ahead…)

As Kanou briefly explains, grafting is taking a piece of one plant, and splicing it onto another.
I’m using roses as examples, but the general idea is the same across any plant. The differences would be in grafting method – some methods are more tricky to pull off because the cut is different – but I’m going to ignore the technicalities (pros and cons, angles of cuts, binding asphalts vs. tape etc.) and go straight to theory because that’s what really matters here.

Terms to know:

budwood - the parent plant you will take material from to implant elsewhere. It’s called budwood because you’re taking from the stem and not the root. This is the plant you want to cultivate.

scion - the piece of the parent plant which you will implant. It’s most commonly a bud or a cane (short section of the stem)

rootstock (often abbreviated to “stock”)
- the donated base of a matured plant that you will graft onto. This is comprised of the roots and a bit of stem. This is the plant that you don’t want growing. It’s role is to aid the scion grow.

Forced flowering/pruning - slightly different concepts, but pretty similar. Forced flowering is the act of continuously cutting off flowers before they age so that the plant is forced into producing more flowers. The plant wants to be pollinated, but you’re cutting off flowers – it has no choice but to keep making replacements. Pruning is the act of cutting off branches to coax the plant into forming a specific shape. If you cut off twigs with buds/flowers, you can trigger the plant to form even more twigs and flowers for a denser bush. Doing this yields a more beautiful plant with a thicker network of foliage, but too much and the plant won’t flower for a long time.


In TG terms:

Budwood= ghoul
Scion=ghoul’s kakuhou
Rootstock= human body
Forced flower/pruning = extensive intentional injury to trigger a denser network of RC pathways forming. It would be intense, concentrated growth in a much shorter time span; different from a ghoul gaining RC paths through training or the trauma/injuries of fighting.

What Does Grafting Do?

The stock is used kind of like a base or an aid for the actual plant you want growing. Maybe that plant you love would take years to mature, or has weak roots. You can speed up maturation by placing a section of it onto an existing structure. The plant doesn’t have to spend months growing roots and gaining a strong stem – that’s already provided by the rootstock. Thus, it can get straight to growing stems, leaves, and wonderful flowers/fruits.

It’s kind of like Frankenstein’s monster in a way. Put some parts together to make a stronger creature.

The thing is, when grafting roses, you put a section (scion/cane) of the rose you want to cultivate onto a donated body (stock) and rather than the scion taking over, it’s actually the rootstock that has a higher chance of persevering. If you look up “Dr. Huey rose,” you’ll find many articles about this phenomenon. It’s a really strong base for grafting, but infamous for making a comeback. The scion will be growing, and the rootstock will start to have offshoots at the graft union (the location where the scion and stock were joined). Rosarians complain about trimming off the Dr. Huey – and seeing it come back even stronger. The scion has to be pretty strong, and the graft union needs to be well taken care of otherwise the grafting will end in failure. Ideally you want the two to merge well and allow the scion to start growing its own network of foliage before you leave the plant to nature’s elements. Once it forms that network, the scion is more resistant to the problem of graft union calluses or the union drying out (I’ll explain these below).

Connecting this to ghoulification, you want the kakuhou (scion) to be strong so that it doesn’t get overpowered and rejected by the human body (stock). Once the kakuhou settles and better integrates in the body (foliage = RC pathways, enzyme production, etc.), it’s more resistant to dying off within the body (dry union).

You can say that Kaneki’s body becoming stabilized in the hospital =  the scion successfully taking to the stock and now having the ability to grow;
Kaneki’s body showing more ghoulish traits (kakugan, ghoulish hunger pangs, kagune) = the scion making foliage of its own – which means if something happens to a part of the plant, there’s more structural support to prevent dying.

“So wouldn’t it be good if the ghoul part is stronger than the human part? That way there’s less chance for rejection and you grow that awesome ghoul ability!”  

That’s not really the point of grafting. If you wanted to grow the same plant, you could just clone it.
And as we know, Kanou is not trying to clone ghouls – he’s trying to fuse ghoul traits into a human body.
Having a strong scion comes with its own risks, which I’ll explain below.

The importance of the stock is long-term stability.

Having a stock means the scion can grow faster than it would if grown from its own roots, and the stock can balance out weaknesses that the budwood (parent plant) had.

  • Example 1: While it might take 5 years for a tree to be mature enough to bear fruit, grafting a piece of the tree onto a rootstock would result in a new fruit-bearing tree in 2 years.
    (It might take 10 years before a ghoul can manifest a kagune, but put the kakuhou in an adult human and they can use a kagune weeks later.)
  • Example 2: The plant has weak roots, is prone to disease, or limited to a certain environment because it can’t absorb nutrients in that type of soil. The rootstock can help give increased immunity to those diseases, and can extract –% more nutrients from the clay-type/sandy/packed soil.
    (A half-ghoul wouldn’t need as much food as a normal ghoul; perhaps the half ghoul can go longer without food or absorbs nutrients more efficiently; perhaps there’s a higher chance for kakuja formation when cannibalizing because the human body base reacts differently to this stimulus.

Simply put, you don’t want the scion to completely overtake the stock, because what’s the point in going to all this trouble trying to fix what the budwood lacks if the scion just grows like it normally would?

In regards to humans/ghouls, you can see what happens if the kakuhou (scion) is too strong by looking at Kanou’s failed projects under that mansion back in the original TG. The kagune eating its host, the human test subjects losing comprehension… not very useful as fighters are they?

It’s a bit of a balancing act for some plant cultivars. Scion and stock need to be compatible – there are even websites for finding plants with recorded lineage so you can make sure the scion will be vigorous enough to counterbalance the rootstock. So Kanou talking about “maybe the Rize-base was stronger than the Yoshimura-base” and “I used strong investigator bodies this time!” really resonates here.

Graft union calluses/drying out =  Rejection of the kakuhou
Apparently, one of the biggest causes of failure is actually the union drying out or becoming callused over time.

  1. The joint wasn’t bound properly and so the graft dries or rots from air or moisture seeping in. 
  2. The scion or stock weren’t cut cleanly leaving splinters/bumps that cause points of obstructed contact.

If you’re not careful and trim the offshoots around the stock with poor technique or too often, two things generally happen:

  1. The stock grows even more offshoots (“suckers”) as a response to trauma. These offshoots will be the first to receive nutrients from the roots. Meaning the scion receives only a fraction of the nutrients it normally would receive. The insufficient nutrients leaves this section weak and more prone to dying.
  2. The plant forms calluses and bulges around the graft union - like scar tissue. You can imagine scar tissue not being very productive in transferring nutrients to the scion portion.

The first two points would probably equate to a subpar technique in attaching the kakuhou, or an unsteady hand in surgery. Perhaps the latter two points could be compared to a delayed organ rejection? The human body aggressively growing more flesh due to trauma… or the body noticing the foreign entity, ceasing to give it nutrients, and attacking it… 

Pruning = pretty and strong, but shorter life expectancy

The main factor in a grafted plant’s lifespan is actually cultivation. This goes for any plant, really – grafted and non-grafted. As I explained in the term definition above, cut the flowers and branches, and the plant will grow more in response. When you go to prize shows, those beautiful award roses are the ones that have been painstakingly sculpted by being pruned over and over to encourage heavy flowering. If you give the plant sufficient nutrients afterward, and leave it alone, it should be fine. However, it won’t flower for years after, and if you try to rush it, the plant won’t last very long. Some rose gardens with continuously blooming flowers are replanted about every 10 years because the rose bushes start to wither from all the forced flowering. In comparison, I’ve read some rose enthusiasts mention that their family’s grafted rose bushes are still going strong after 50 years despite less-than-ideal environmental conditions.

If you want to see a more ordinary example, go to a nursery or a home goods store that sells plants. The perennial flowers are cultivated in a lab or larger nursery under their preferred conditions and cut so that customers will have a beautifully flowering plant now. That same bush most likely won’t have as many blooms the next year because it was made to produce so many flowers the year before.

You might think of extensive pruning as trauma that the plant needs to heal from.
You might think of intentional trauma for the sake of RC path building as a technique that would be best paired with a large dose of after-care and healing time.

Kanou’s Life-expectancy statement
This horticulture technique of pruning/force flowering plants is probably one of the ideas that Kanou’s life-expectancy statement comes from. Obviously he hasn’t had hundreds of successful half-ghouls to test and see if “pruning” will shorten lifespans. He probably knows about the Sunlit Garden and can draw some conclusions about hybrids from that, but those children were born as hybrids – they aren’t grafted humans like Kanou’s experiments– which means their genes are different. That is to say, he doesn’t have enough empirical evidence to know for sure that “pruning” will affect an artificial half-ghoul’s lifespan in the same way that the mixing of genes affects a natural born hybrid.

Kaneki - the miracle 1-in-a-million graft plant
If we were to compare Kanou’s half-ghouls to graft plants, Kaneki is not just a normal graft with amazing results. He would be a successful graft-chimera. A graft chimera starts out as an ordinary graft attempt, but somehow the resulting plant has traits from both sides, plus it’s own special traits. For example, a normal graft plant could have white flowers from the scion branches and red flowers from the rootstock offshoots, but the plant would never have pink flowers because you’re not actually mixing genes while grafting. In comparison, a graft chimera would have both the red and white flowers, and have branches that produce flowers with a blend of traits.
The main point I want to focus on isn’t about how genes cross in a body, but that graft-chimera are accidental, and replication is exceedingly difficult (near impossible for some types of plants). They’re so special, in fact, that the grafted plant has its genus name changed when its confirmed. 

Half-ghouls like Kurona and Nashiro are successful grafts, but don’t show the unique traits that Kaneki, a graft-chimera has. They’re great grafts – Rize’s kakuhou is working correctly inside their body – but “floppy” when compared to Kanou’s spontaneous graft which resulted in something more. It’s not just that Kaneki has a seamless union between kakuhou (scion) and body (rootstock), or shows both ghoul and human traits, or has impressive vitality compared to other artificial half-ghouls (Kanou’s “graft plants”). It’s that he shows those traits plus something uniquely complex.

This grafting idea Kanou has is kind of like the pursuit to recreate a rare graft-chimera. Takizawa is his newest specimen, and Chapter 90 shows us a glimpse at Kanou’s attempts to coax graft-plant-Takizawa into becoming a graft-chimera-Kaneki. He’s #2 once again – an attempted copy of a one-of-a-kind masterpiece.


Biologically speaking, some portion of Kaneki’s growth is likely due to processes covered in the field of epigenetics rather than this graft-chimera phenomenon of fused genes. Humans and plants work differently, so the genetic processes that go on between the meristem cells of plants wouldn’t be directly applicable to humans.
silverbulletsama has wonderful posts about genetics/epigenetics that discuss how gene expression affects the human body. In particular, the information about the genotype of a transplanted organ, how a kakuhou affects the body through inhibitors/enzymes, and environmental factors affecting gene expression, would be more appropriate for this idea of Kaneki being different from his fellow artificial half-ghouls. I highly recommend reading through the posts because they really help with understanding what might be happening in ghoul/half-ghoul biology – after all, our TG characters aren’t plant people that follow the rules of horticulture!   

In conclusion…

Grafting is complex, and just because a plant is grafted doesn’t mean it will be short-lived. Pretty much the main determiner besides the site of the graft becoming callused, is how much the plant is cut back and pruned. If you go all manipulative-creator on it (pruning, shaping, coaxing more branches to form, cutting the flowers to trigger bigger blooms), the plant shows beautifully for a while, and then dies out.

Of course, people and plants don’t work the same, but if you look at grafting plants as a metaphor for Takizawa and Kaneki’s situations, Takizawa is kind of in dangerous territory, but Kaneki should be fine-ish.  Kaneki’s situation more resembles a case of steady growth, trauma, steady growth; whereas Takizawa’s resembles vigorous pruning in the formative stages (intense trauma with forced regeneration over an extended period of time) followed by steady growth.

I wouldn’t be so worried about Kaneki as long as he has access to enough food to heal and doesn’t get his limbs cut off regularly. *knocks on wood*

(In conclusion, Kanou is actually a plant enthusiast striving to recreate that miracle cactus called Kaneki, and Takizawa is his new baby plant.)

8

People reject organs every day. Lungs are especially tricky. You know, some person is brain dead on a ventilator and we’re all acting like, “Oh, great, just put those lungs into Emma.” It doesn’t work like that. What if I’m not a good match? That’s more likely to happen than not. Then I’ve wasted this poor dead person’s lungs, and whatever little bit of life I have left here on this earth.

Kaneki's Medicine + X-Ray Scan

Well, after reading the whole manga again, I started noticing like Kaneki apparently always ‘have’ to drink his meds?

And Kanou always asked about it, frequently…

In a way, it feels a bit… too suspicious? It’s Kanou after all..

Turned out they’re just immunosuppressant, in which you take after you get organ transplant so that you won’t reject the organs. It something you must absolutely take daily… the rest of your life probably. (I actually don’t know, maybe I should look it up more)

That said, were they really immunosuppressants? What if Kanou has been giving him something else? Even ghouls must take immunosuppressants? Do other half ghouls beside Kaneki take it? Is he still taking it? What would happen if he start to stop taking it. Would the kakuhou start rejecting him and eat his body? Many potential questions raised.


Oh, and we also have an X-Ray scan of Kaneki in Kanou’s office here. And from the look of it, it actually more like a scan of his Rc cell veins like it is shown in the recent chapter. If you look at his right side (your left) lower abandoned there would be a bright area, which makes sense because the surgery scar is there. And also before this visit with the doctor, he have been kicked by Nishiki there, punched by Touka, and another kick by Amon, so basically that area should flare up with Rc cell veins at that time.

And let’s say that is indeed the Rc cell veins scan, then Kanou knows that when a half-ghoul is injured, they become stronger, which explains his treatment toward the twins, (and then Seidou too probably.) And with that, he’s probably trying to build an half-ghoul army.. through pain and torture…

The human leukocyte antigen (HLA) system is the locus of genes that encode for proteins on the surface of cells that are responsible for regulation of the immune system in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and has many other functions.

The HLA genes are the human versions of the major histocompatibility complex (MHC) genes that are found in most vertebrates (and thus are the most studied of the MHC genes). The proteins encoded by certain genes are also known as antigens, as a result of their historic discovery as factors in organ transplants. The major HLAs are essential elements for immune function. Different classes have different functions:

  • HLAs corresponding to MHC class I (A, B, and C) present peptides from inside the cell. For example, if the cell is infected by a virus, the HLA system brings fragments of the virus to the surface of the cell so that the cell can be destroyed by the immune system. These peptides are produced from digested proteins that are broken down in the proteasomes. In general, these particular peptides are small polymers, about 9 amino acids in length.[citation needed] Foreign antigens presented by MHC class I attract killer T-cells (also called CD8 positive- or cytotoxic T-cells) that destroy cells.
  • HLAs corresponding to MHC class II (DP, DM, DOA, DOB, DQ, and DR) present antigens from outside of the cell to T-lymphocytes. These particular antigens stimulate the multiplication of T-helper cells, which in turn stimulate antibody-producing B-cells to produce antibodies to that specific antigen. Self-antigens are suppressed by regulatory T cells.
  • HLAs corresponding to MHC class III encode components of the complement system.

HLAs have other roles. They are important in disease defense. They are the major cause of organ transplant rejections. They may protect against or fail to protect (if down-regulated by an infection) against cancers. Mutations in HLA may be linked to autoimmune disease (examples: type I diabetes, coeliac disease). HLA may also be related to people’s perception of the odor of other people, and may be involved in mate selection, as at least one study found a lower-than-expected rate of HLA similarity between spouses in an isolated community.

Aside from the genes encoding the 6 major antigen-presenting proteins, there are a large number of other genes, many involved in immune function, located on the HLA complex. Diversity of HLAs in the human population is one aspect of disease defense, and, as a result, the chance of two unrelated individuals with identical HLA molecules on all loci is very low. HLA genes have historically been identified as a result of the ability to successfully transplant organs between HLA-similar individuals.

SPOILER NEW CHAPTER GAIDEN

YENWSJ156815

End Naruto Weekly Shonen Jump, 15 (chapters) 6/8/15 (will finish)

NG C7003 P197 B4 W5 - (Shin)

Naruto Gaiden chapter 703, page 197, balloon 4, word 5.

OP C789, P32, B15, W5 - (is)

One Piece chapter 789, page 32, balloon 15, word 5.

WT C104, P14, B3, W3 - (not)

World Trigger chapter 104, page 14, balloon 3, word 3.

REOS P17, B2, W10 - (¿an?)

 page 17, balloon 2, word 10.

NG C7006, P72, B10, W4 - (Uchiha)

Naruto Gaiden chapter 706, page 72, balloon 10, word 4.



SU C3, P179, B11, W5, L1-3

chapter 3, page 179, balloon 11, word 5, letter 1-3.

GH C6 P157 B12 W5 L7 (z)

Gakkyu Hotei chapter 6, page 157, balloon 12, word 5, letter 7.

SOTE C29 P34 B4 W1, L1-2

Seraph of the End chapter 29, page 34, balloon 4, word 1, letter 1-2

T C320, P25, B15, W3 - (arm)

Toriko chapter 320, page 25, balloon 15, word 3

OP C789, P32, B15, W5 - (is)

One Piece chapter 789, page 32, balloon 15, word 5 

RV C2 P205 B5 W2

Rosario Vampire chapter 2, page 205, balloon 5, word 2 

NG C7003, P197, B4, W5 - (Shin)

Naruto Gaiden chapter 703, page 197, balloon 4, word 5 



NG C7003 P197 B4 W5 - (Shin)

Naruto Gaiden chapter 703, page 197, 4 balloon, 5 word. 

OP C789 P32 B15 W5 -  (is)

One Piece chapter 789, page 32, 15 balloon, 5 word.

BC C10 P171 B10 W2 - (special)

Black covers chapter 10, page 171, balloon 10, word 2.   

N C161 P229 B3 W5

Nisekoi chapter 161, page 229, 3 balloon, 5 word.

WT C105 P14 B3 W3 - (not)

World Trigger chapter 105, page 14, ballon 3, word 3.

NG C7002 P67 B4 W3 L1 -  ( r )

Naruto Gaiden chapter 702, page 67, 4 balloon, 3 word, 1 letter. 

GH C12 P257 B6 W3 L1-5 (eject)

Gakkyu Hotei chapter 12, page 257, balloon 6, word 3, letter 1-5

FW C112 P13 B7 W4 -  (any)

Food war chapter 112, page 13, balloon 7, word 4.

NG C7006 P85 B2 W3 - (organ)

Naruto Gaiden chapter 706, page 85, 2 balloon, 3 word.

NG C7006 P85 B1 W1 - (transplant)

Naruto Gaiden chapter 706, page 85, 1 balloon, 1 word. 



FW C113 P134 B1 W1 -  (They)

Food War chapter 112, page 134, balloon 1, word 1. 

BE C66, P222, B7, W3 - (meet)

Blue Exorcist chapter 66, page 222, balloon 7, word 3.

NG C7002 P67 B6 W3 L1-6 -  (Yamato)

Naruto Gaiden chapter 702, page 67, 6 balloon, 3 word, 1-6 letter.

NG C7002 P67 B4 W1 L1-10 -  (Orochimaru)

Naruto Gaiden chapter 702, page 67, 4 balloon, 1 word, 1-10 letter.

BE C67 P28 B3 W2 L1-2 - (su)

Blue Exorcist chapter 67, page 28, balloon 3, word 2, letter 1-2

YGOZ C52 P169 B5, W1 - (i)

Yu-Gi-Oh Zexal chapter 52, page 169, balloon 5, word 1.

C C1 P350 B4 W1 L4-6 - (get)

chapter 1, page 350, balloon 4, word 1, letter 4-6.

BE C67 P28 B3 W2 L1-2 - (su)

Blue Exorcist chapter 67, page 28, balloon 3, word 2, letter 1-2

SOTE C33 P74 B5 W6 - (and)

Seraph of the End chapter 33, page 74, balloon 5, word 6.

BOF C4 P261 B4 W3 - (ju)

chapter 4, page 261, balloon 4, word 3.

TG C1 P223 B1 W2 L3 - (u)

Tokyo Ghoul chapter 1, page 223, balloon 1, word 2, letter 3.

C C1 P303 B6 W8 - (go)

chapter 1, page 303, balloon 6, word 8.



SPOILER

Naruto Gaiden will have 15 chapters and it will end the 6th of July.

Shin is not an Uchiha.

… arm is … Shin

Shin is special ….. not reject any organ transplant.

They meet Yamato, Orochimaru, Suigetsu and Juugo.

So, my mother is a biologist, and she told me that umbilical cords possess stem cells, which if you don’t know, can be used to replace lost body parts or organs.

She said: “If the umbilical cord is kept on an adequate space, it can be used in the future for, for example, if a kid loses a kidney for a or b reason, you can take his umbilical cord, extract the stem cells on it, inject it on the needed place, and a new kidney would start growing.

Also she mentioned that only applies to your own umbilical cord, but Shin doesn’t reject organs/transplants from others.

So, as another smart tumblr user already stated, I think they kept Sarada’s umbilical cord where and how they got it is still a mystery in order to use it on Shin. Maybe to make the Sharingan appear all over his body or what-not.

April 24, 1916 - First Day of the Easter Rising

Pictured - As a wrecked barricade blazes behind them, British troops fire and advance down a Dublin street.

Dubliners woke to the sound of gunfire on Easter Monday as 1,500 insurgents rose up against British rule. The rebels, members of the pro-independence, anti-British Irish Volunteers and Irish Citizen Army, seized key buildings in the city center, making their headquarters at the General Post Office, which soon had two green flags fluttering above it, emblazoned with the words “Irish Republic”.  It was the beginning of the Easter Rising, an attempt by Ireland’s radical nationalists to establish an independent Irish state that lead to six days of bloody street battles in Dublin and a few other areas throughout the country.

The Rising was spearheaded by members of the Irish Republican Brotherhood, a revolutionary organization which rejected the position of milder independence groups, which wanted to help Britain in the First World War, after which they hoped the British would implement a Home Rule bill, granting Ireland self-government.  The leaders of the IRB, however, believed that only a violent revolution could win Irish independence.  Lead by Irish teacher and poet Pádraig Pearse, and James Connolly, the commander of a nationalist paramilitary called the Irish Volunteers, the revolutionaries planned an uprising to take place on Easter week, aimed at ending British control in Ireland while Britain was distracted by the war. 

Planning for the rebellion, however, had not been well organized.  The Royal Navy had captured a German ship bringing modern rifles to the rebels, and the British had captured Sir Roger Casement, one of the rebel leaders.  London knew that a rebellion was planned for Easter based on these captures and radio signals intercepted from Germany, which supported the rebels.  London telegraphed orders to officers in Ireland to arrest leaders of the independence movement on Monday, April 24.

Many members of the Irish revolutionary movement argued against launching the Rising, since it was known that the British were aware, and because of the capture of the German ship carrying modern Mosin-Nagant rifles with which the rebels had planned to arm their troops.  Most of the Irish Volunteers and Citizen Army troops only had handguns or old Mauser rifles smuggled in from Germany before the war, that had to be reloaded with every shot and sent up great plumes of smoke, plus a smattering of more up-to-date arms and hand-grenades.  Eoin MacNeill, the Chief-of-Staff of the Irish Volunteers, believed that the uprising was hopeless and published orders in all Sunday newspapers warning Irish Volunteers not to take part in any armed rebellion.  Because of MacNeill’s order, far fewer rebels took to the streets on April 24 than planned.

The seven-man Military Council of the IRB met to discuss whether to call off the operation, but news of the incoming arrests by the British government persuaded them to give the go-ahead.  On Monday, April 24, 1,500 rebels, divided into several brigades and including 90 women, captured the GPO and other strategic buildings in Dublin city-center.  Pearse stood outside the GPO and read out a proclomation announcing the creation of the Irish Republic, which began:

“Irishmen and Irishwomen, in the name of God and of the dead generations from which she receives her old tradition of nationhood, Ireland, through us, summons her children to her flag and strikes for her freedom.”

Somewhat unwisely, a further paragraph praised Germany, the Republic’s “gallant Allies”, a choice of words which must have upset many Dubliners whose fathers, brothers, and sons, in the words of one historian, “had been fighting those allies in Europe for the past twenty months.”

Though there were far fewer than hoped, the rebels planned to hold the center of Dublin against British counterattacks, defending from positions such as the GPO, the Four Courts law building, the seat of the government at Dublin Castle, the armory at Phoenix Park, and a wireless station, which sent out a Morse code message announcing the birth of the Irish Republic.  Squads from the Irish Citizen Army, no doubt influenced by news from the front, dug trenches in St. Stephen’s Green.  It was not long before their defenses were put to the test.

British guards in Dublin had been overwhelmed by the initial outburst of violence, and the Dublin Metropolitan Police had been pulled off the street after the rebels killed several unarmed policemen.  Although the rebels had hoped to spark a popular uprising, they had very limited public support. The first detachments of British reinforcements to arrive were Irish soldiers of the two most-recently raised Irish regiments, the 3rd Royal Irish Rifles and the 10th Royal Dublin Fusiliers (including your author’s great-grand uncle, then a lance-corporal with the Royal Irish Rifles).  Taken aback and surprised at the rebellion, most Dubliners welcomed the British troops openly, cheering them on in the streets, while a handful of armed students successfully defended Trinity College from capture.  One Irish soldier spotted his wife and children in the crowd and gave them a happy wave.  A few minutes later, he lay dead in the street, killed by a rebel sharpshooter.

A rebel squad of Irish Volunteers on-top the roof of the College of Surgeons. Armed with forty-year old single-shot Mauser rifles, they were outgunned from the start.

The British counter-attack was uncoordinated on the first day, but the British troops had weight of numbers, superior weaponry, and more training and experience on their side.  Nevertheless, they made little impact on the rebel positions on day one.  A troop of British cavalry, sent to investigate the position at the GPO, took casualties from rebel fire, as well as a platoon of elderly reservists. A British gunboat in the River Liffey retaliated by wrecking the rebel position at Liberty Hall. 

Besides constant sniping from rooftops and barricades, the first day of the Easter Rising ended with little other significant combat. Outside of Dublin, a few minor firefights flared up in other cities and in the countryside.  Meanwhile, thousands of British troops continued to pour into Dublin, preparing to fight the next day.  Civilians suffered worse in the claustrophobic city battle, from both sides: besides policemen, the rebels shot dead a number of civilians attempting to dismantle their barricades, while the British troops gunned down a nurse, Margaret Keogh, as she tried to tend to wounded people in the street. 

Please Don’t Let the Political Revolution Die

Back on March 15th we told everyone we didn’t think Bernie could win. We wanted to be wrong and a few times after that, most notably before New York, I thought we might be. Unfortunately we were not wrong and barring something crazy, the nominee is going to be Hillary Clinton. Before some of you start typing me angry messages, let me explain why those angry messages are counterproductive. Not when you send them to me, but when you leave them around the internet for other people to see and take in.

Each time we made those posts saying we thought Bernie couldn’t win, we did so against the urging of the official campaign, and against what we knew our followers wanted to hear. It’s unfortunate but a certain part of the campaign process is intentionally blurring the lines and intentionally making your person seem better or more worthy of praise, it’s just how elections work. We did it to an extent, but personally I think being unrealistic with your expectations of victory is unfair. Bernie Sanders hasn’t dropped out yet, but he won’t be the nominee, he lost the primary process fair and square. The process IS rigged. That’s a fact. He still lost under the rules of that rigged process. It was rigged before Bernie entered and he campaigned knowing it was rigged. The behavior of people like Debbie Wasserman-Schultz and the media made it all worse. That’s also a fact. 

Holding your fingers in your ears and screaming at anyone who says Bernie lost won’t change that fact and all it does is legitimize everything our detractors say about us. 

We don’t like this. We’ve been posting Bernie content for over a year. Every day hours of my day have been devoted to Bernie and his cause. Every single day, for over a year. Even before he announced we were busy campaigning for him. We’ve been here from the beginning. We’ve watched his campaign grow from 3% in the polls to pose a real challenge to the biggest political machine in the history of the United States. We’ve watched his message change from a pretty singular focus on income inequality and Scandinavian Socialism, to a broad focus on economic, social, racial, and environmental justice. We helped Bernie continually defy the odds and forever change the political landscape of the United States. We can’t stop now. 

Throughout the entire primary process people branded us as idealistic, as too outlandish, as crazy, as unrealistic. If this campaign has taught you anything, remember that Bernie’s ideas are none of those things. The behavior I’ve seen in the last week, totally is. The political process sucks sometimes, I held my nose while I voted for Obama in 2012. The country is hurting and I’m not going to tell you who to vote for. Being vocally anti anything but Bernie at this point, is unrealistic. It shows how little some people know about American politics and the system we work within. I realize we’re trying to change that system, but that’s the whole point, it takes more than brute force. 

We need to organize. We need to reject the status quo and seek better information and more nuanced discussion. We need to consider the views of people we might consider outlandish. We need to focus on solutions, not conflict and sensationalism. Screaming #BernieorBust on Twitter and saying you’ll vote for Donald Trump because $hillary is evil, WON’T GET US ANYWHERE. It’s inviting, sometimes it feels really good, especially after everything that’s been pulled on us, but it won’t change the country. 

Being realistic and thoughtful is what will change this country and that is exactly what Bernie represents, no matter what anyone says. Nothing Bernie has said is unrealistic. Don’t let them take that away from us by being sore losers. Don’t let them brand the entire movement as not legitimate because of the vocal few who want to tear everything down in these next few weeks. This campaign has been unbelievably successful. Please continue to advocate for those ideas in every way and please understand that bashing people for having different opinions just proves everything the opposition has been saying about us.