It is known that salt is important for cognitive function. Although some studies do link a lower level of sodium with a reduction in blood pressure and heart disease, studies have also found that low levels of sodium could impair memory and brain function.
Study identifies new link between Down syndrome and Alzheimer’s disease.
Now, a study from researchers at Temple University has shown that
dementia in Down syndrome involves defects in a regulatory enzyme known
as γ-secretase activating protein (GSAP), which also malfunctions in
Alzheimer’s disease. The team state that the work could soon lead to the
development of a specific GSAP-targeted therapy that is capable of
safely mitigating dementia in Down syndrome.
In Kennedy’s disease, the muscle cells and motor neurons, which are also linked to muscle function, are damaged as a result of the accumulation of androgen receptor fibers, a process that causes them to die. Many aspects of diseases involving aggregates, such as Alzheimer’s and Parkinson’s, are unknown. In this regard, Kennedy’s disease is in a worse position because it is a rare condition that…
It is known that the hippocampus is central to episodic memory and spatial navigation both of which rely on sequences of spatiotemporal information. Spatiotemporal trajectories are coded by theta sequences, ordered series of hippocampal place cell spikes that reflect the order of behavioural experiences. Theta sequences are thought to be organized by co-occurring gamma rhythms. However, how…
Reporting on their study with lab-grown human cells, researchers at The Johns Hopkins University and the University of Maryland say that blocking a second blood vessel growth protein, along with one that is already well-known, could offer a new way to treat and prevent a blinding eye disease caused by diabetes.
The team state that the disease, diabetic retinopathy , is the most common cause of…
When the nervous system is developing neurons send their axons, the parts of neurons that make up the body’s nerves, to make connections with other neurons. For instance, a neuron in the dorsal spinal cord grows towards attractive signals coming from the ventral spinal cord and cross the midline. The front ends of growing axons have ‘growth cones’ that sniff out attractive and repulsive signals.…
Nano-magnetic cell targeting used to treat TBI in animal model.
Now, researchers from the University of Maryland and the Veterans
Administration Maryland Healthcare System state they have successfully
guided human neural progenitor cells (hNPCs) to injured brain areas
using nano-magnetic cell targeting.