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Nanofilm Ultra Clarity Micro-Fiber Lens Cloth

Nanofilm Ultra Clarity Micro-Fiber Lens ClothNanofilm Ultra Clarity Micro-Fiber Lens Cloth Click Here for More Information on Nanofilm Ultra Clarity Micro-Fiber Lens ClothAbout NanofilmRecognizing the growing need for a new approach to old-style coatings and conditioners for the ophthalmic industry Nanofilm developed ultra-thin coatings to protect enhance and condition this new breed of optical surfaces and coatings. In tandem with the ophthalmic coatings the company developed lens cleaning care and refresher products. Today Nanofilm’s surface care products are distributed around the world for the care of electronic displays such as computers cell phones and MP3 players as…

A Combined Negative and Positive Enrichment Assay for Cancer Cells Isolation and Purification

Cancer cells that detach from solid tumor and circulate in the peripheral blood (CTCs) have been considered as a new “biomarker” for the detection and characterization of cancers. However, isolating and detecting cancer cells from the cancer patient peripheral blood have been technically challenging, owing to the small sub-population of CTCs (a few to hundreds per milliliter). Here we demonstrate a simple and efficient cancer cells isolation and purification method. A biocompatible and surface roughness controllable TiO2 nanofilm was deposited onto a glass slide to achieve enhanced topographic interactions with nanoscale cellular surface components, again, anti-CD45 (a leukocyte common antigen) and anti-EpCAM (epithelial cell adhesion molecule) were then coated onto the surface of the nanofilm for advance depletion of white blood cells (WBCs) and specific isolation of CTCs, respectively. Comparing to the conventional positive enrichment technology, this method exhibited excellent biocompatibility and equally high capture efficiency. Moreover, the maximum number of background cells (WBCs) was removed, and viable and functional cancer cells were isolated with high purity. Utilizing the horizontally packed TiO2 nanofilm improved pure CTC-capture through combining cell-capture-agent and cancer cell-preferred nanoscale topography, which represented a new method capable of obtaining biologically functional CTCs for subsequent molecular analysis.

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