morphogen

The Morphogenic Field is a term we use to describe the field of energy around the body. It is an extension of the electrical energy of the nervous system. The brain is an electrical generator with its own field of energy that extends away from the physical body. Many cultures and disciplines recognize this field and give it other names. When people discuss auras, chakras, life force or chi, they are possibly talking about this same energy field.

Miles Upshur’s Notes be Like

Motherfucking Martin Archimbaud jesus christ fuck dude motherfucking Mount Massive bullshit jesus can you fucking believe this shit Goddamn created the Morphogenic Engine and variants and shit right fucking naked-ass twins goddamn rowing the boat Fuck yo shit I can’t even fucking believe this shit have you seen this shit fuck I just watched this shit fuck Martin Archimbaud man Motherfucking Waylon Park Waylon Park you put in the time fuck put in the time motherfucking wrote shit with his bare hands fucking best friend shit Martin Archimbaud. I’m very tired.

No man I’ll just talk about the Walrider all day shit man you have to be so interested in the shit I have to say about the Walrider fuck dude I just saw it like a year and a half ago fuck Jeremy Blaire man he fucked over Waylon Park Crazy Naked-ass twins rowing Samuel La Flame did the soundtrack Fuck this guy who invented the Morphogenic Engine I don’t like dying I can’t think of who the fuck invented the Morphogenic Engine I can only think of the guy who played the guy who invented the Morphogenic Engine who the fuck invented the Morphogenic Engine?

RUDOLF WERNICKE

highkeyflammable  asked:

hey i dont know if youre still doing the headcanons but do you have any for if the kids were super heroes/villains and what their powers would be?

  • Jay has a form of pyrokinesis, mainly he is able to generate fire through his hands. At first it was triggered during fits of rage but eventually he learned to control it. He is also resistant to heat and flame.
  • Evie is a morphogene. She is able to alter her physical appearance and voice at will. Because of the pressure from her mother she’s mainly learned to use these powers to try to “perfect” herself. It’s painful for a morphogene to hold a change for too long but when you practice as much as she has you learn to ignore how much beauty hurts.
  • Carlos is a zoolinguist and manipulator. Not only can he communicate with animals but also control their minds/bodies. He got this ability from his mother and although she was limited to dogs, he shows signs of greater power. He’s also quite the techie.
  • Mal has ergokinesis, or the ability to craft tools/weapons out of pure energy with her mind. This also extends to the ability to use the energy around her to manipulate objects. It’s easily passed off as “magic”.
  • The four of them worked individually for a while committing petty crimes like theft, money scams, minor eco-terrorism, but eventually came together for a larger job. However, when things get out of hand due to some much bigger baddies they end up saving the day, and it felt kinda good. The Rotten Four end up forming a “Robin Hood” type of group, committing crimes against the people of Auradon to help the greater good.

In the 1960s Lewis Wolpert devised a model to describe basic pattern formation in development. This model was known as the French Flag Model. It is a useful model as the formation of the three colours of the flag can be used to understand the formation of the three germ layers present in embryos. The first thing to note is that no matter what size the flag, it still maintains the same basic pattern. One third will be blue, one third white and one third red, in that order, along one axis. Second, in a line of cells with defined boundaries, each cell has the potential to differentiate into a blue, white or red cell. Wolpert set out to try and explain the mechanism behind how the cells know which colour they should differentiate into. Cells must receive some form of information to deduce where they are situated within the flag model, and then according to their genetic program interpret this information by differentiating into one of the three cell types.

There are two stages of pattern formation, first the cells have to establish their position and then they have to interpret this information. The fact that a clear distinction has been made between these two processes implies that there is no set relation between a cells position and the how it interprets the information it is sent. Thus in a different set of parameters these cells are capable of producing a completely different pattern. Wolpert devised a simple way to explain how a cell establishes its orientation, based on the gradient of a substance. If the concentration of a chemical substance decreases from one end of the flag to the other a cell could work out where exactly it was positioned in relation to the boundaries. This would be due to the amount of chemical substance the cell received. This Chemical substance is known as a Morphogen. Morphogens are described as substances in embryonic tissues that form a concentration gradient and influences morphogenesis.

In the French Flag Model we assume the concentration is greatest at one end and lowest at the opposite end and so the morphogen diffuses at a constant rate down the line of cells. It is also safe to assume that the cells respond to threshold concentrations of the morphogen. Above a particular concentration threshold blue cells will form, whilst below this concentration threshold but above another, white cells will form. Below both these concentration thresholds red cells form creating the complete French Flag pattern.

The threshold could be one of two things; the specific amount of morphogen need to bind to receptors on the cells in order to activate intracellular signalling cascades, or differing concentrations of transcription factors, which are required to activate certain genes within the cells.

This model highlights two important features of morphogenesis. Firstly, even if the length of the line of cells varies, patterns will still from in the correct proportions, as long as defined boundaries are present with constant but differing concentrations of morphogen at either end. Secondly the pattern could regenerate itself to the complete original form after being cut in half, as long as the defined boundaries and concentrations were re-established. 

[Adapted from Wolpert Principles of developmental Biology]



Retinoic acid gradient visualized for the first time in an embryo

Researchers from the RIKEN Brain Science Institute in Japan report a new technique that allows them to visualize the distribution of retinoic acid in a live zebrafish embryo, in real-time. This technique enabled them to observe two concentration gradients going in opposing directions along the head-to-tail axis of the embryo, thus providing long-awaited evidence that retinoic acid is a morphogen.

A morphogen is a substance governing the pattern of tissue development in the process of morphogenesis, and the positions of the various specialized cell types within a tissue.

Since morphogens diffuse through the tissues of an embryo during early development, concentration gradients are set up. These gradients drive the process of differentiation of unspecialised (stem) cells into different cell types, ultimately forming all the tissues and organs of the body.

Zero escape: Series Trailer (Translation)


https://www.youtube.com/watch?v=s8oN6XBE7SU

CAUTION: this trailer contains spoilers for “Zero escape: 9 hours 9 person 9 doors” and “Virtues last reward”


Quick translation for the new trailer! 

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