Fallout 3 is actually a really sad game when you think about it.
The main character, The Lone Wanderer, is an incredibly tragic character.

The Lone Wanderer’s mother dies giving birth to them. Their father runs away leaving them stranded and alone, launched into a dangerous, cruel, and unforgiving world of monsters, both human and otherwise. 

Death, destruction, chaos, madness, brutality, gore, mutilation, agony, poverty, loss, and darkness. The Lone Wanderer witnesses these things and experiences their fair share of it personally.

And then, after crossing the entire hellish wasteland at least twice over, they find their father, only to have him taken away from them again. But this time it’s permanent. After crossing a ruined world of nuclear ash, their own father sacrifices himself and they have to watch him slowly die, powerless to stop it.

Their childhood friends disown them and banishes them from their own home. The man who murdered their father somehow lived. There alone in a world that will kill them even for being a morally just person.

And if you play Point Lookout, there’s a hallucination sequence that is especially creepy. You find ‘bubbleheads’ that read out mocking descriptions.

Intelligence: “Tsk. Tsk. Walked right into another trap. Exactly how stupid are you?" 

Strength: "This is one situation you’re not going to be able to fight your way out of." 

Endurance: "Keep it up, you’re almost there… wherever 'there’ may be… probably nowhere." 

Agility: "Isn’t it funny how everyone you get close to ends up leaving?" 

Perception: "This doesn’t look right, not right at all." 

Charisma: "Blech. If my kid looked like that, I’d abandon it too." 

Luck: "Dead mother, life in a post-nuclear Wasteland and not a friend in it. Yeah, you aren’t exactly blessed." 

The Lone Wanderer has it rougher than any other character I’ve seen in a video game. 

First we had Solid Snake

Then we were introduced to His twin brother, Liquid Snake

And his brother from another mother Solidus Snake

And a pussy who once went by the codename snake once (raiden)

Then we were re-introduced to big boss as naked snake

Then Solid Snake got old and called himself Old Snake

But in 1974, naked snake dropped naked from his name and just became snake

In the Phantom Pain we’re getting Punished AND Venom Snake

But in 2281, prepare to be introduced to…