Biohackers gear up for genome editing

“A complete lack of formal scientific training has not kept Johan Sosa from dabbling with one of the most powerful molecular-biology tools to come along in decades.Sosa has already used CRISPR, a three-year-old technology that makes targeted modifications to DNA, in test-tube experiments. Next week, he hopes to try the method in yeast and, later, in the model plant Arabidopsis thaliana

Hailed for its simplicity and versatility, CRISPR allows scientists to make specific changes to a gene’s sequence more easily than ever before. Researchers have used CRISPR to edit genes in everything from bacteria to human embryos; the technique holds the potential to erase genetic defects from family pedigrees plagued by inherited disease, treat cancer in unprecedented ways or grow human organs in pigs. One researcher has even proposed modifying the elephant genome to produce a cold-adapted replica of the long-extinct woolly mammoth.

Such feats are beyond the reach of do-it-yourself (DIY) ‘biohackers’, a growing community of amateur biologists who often work in community laboratories, which typically charge a recurring fee for access to equipment and supplies. But CRISPR itself is not. Driven by an inventive spirit that inspires them to fiddle with yeast to alter the flavour of beer, build art installations out of bacteria or pursue serious basic-research questions, these amateurs cannot wait to try the technique.

“It’s, like, the most amazing tool ever,” says Andreas Stürmer, a biohacker and entrepreneur who lives in Dublin. “You could do it in your own home.”

anonymous asked:

any advice on how to pass biology this semester, im gonna die

mind if I ask what level of biology you’re at? (reg hs bio, or AP bio, or uni bio)

Regardless, I think these are some basic tips that saved my life in bio (I’m a very visual + auditory learner btw so this is based on that!)

    • Draw a diagram of everything. Literally biology only made sense to me when I drew it. Even if it was a simple thing––draw it! Whether you draw a detailed pic, or a rough mind map, or just a doodle, it will help a lot.
  • Colour code your notes!
    •  Not your original notes, maybe, but when you’re studying for a test or exam, I suggest making new (more summarized) notes and colour coding them. This is also where diagrams really help.
  • Find online websites that animate the specific procedures you’re studying! 
  • Bio has memorization!!! BUT don’t just memorize!!
    •  If you just focus on memorizing the names and parts and steps, but you don’t understand, you will be screwed if you have to answer a question that asks you to apply your knowledge to a case.
  • Watch youtube videos that explain processes 
    • (khan academy is usually your best bet in this case! they animate as they explain but they’re a lot more straightforward)
  • Say it out loud.
    •  To your imaginary friend? Type it up and pretend you’re explaining it to someone? Actually explain it to someone? This is the best way to find out if you actually understand it: if you can explain it to someone else, then you’re great to go. Also bonus if you can either make questions to challenge yourself or have someone ask you questions c:
  • Extra tip: try to think a step further when you study!! 
    • If you’re studying, say, meiosis, try to think about what may happen if something goes wrong (assuming your teacher didn’t teach you that) and then try to see if you can apply what you learned to that. Don’t be too harsh on yourself with this, I just think it’s a great way to see if you actually understand the material

Profile templates for use. I use them for sales bios. But you’re free to use them for whatever. If you DO use my templates I ask that you do not edit the code part of them. I tried to make them as user friendly as possible. We’ll see how well that worked out. If you have questions feel free to ask (though there are some spacing issues on two of them that I don’t understand or know how to fix…)

anonymous asked:

could you give me some tips on how you got an A in biology a level as im going to be studying it next year and i have no idea how to organise my work and time, thank you!


I’m not 100% sure how you get an A in biology but I will say what I did for revision in Biology. 

In Lessons:

A lot of this is more what my teachers did rather than me, but class time is a lot of your time.

  • I get all my things out as soon as I get in so I can start as soon as possible.
  • In class I make rough notes on A4 paper. I don’t write everything down and I don’t spend ages on them, so I can listen closer to the teacher. 
  • I try to actively listen throughout the lessons and focus hard. I personally prefer putting extra effort in lessons even though it tires me out.
  • I do talk to my classmates. Partly about Biology and partly not, but make sure you don’t talk too much about the non-biology part.
  • While I wait outside I might look at flashcards on my phone if no one else is there yet.

In Free Periods:

  • Use your free periods!!
  • I had a free period two lessons before my Biology lesson and I used to spend it doing my homework. I also had one afterwards, which I used to review the work I did the past lesson.
  • Most of my rewriting notes was done in my free periods. I used the library as it’s quiet and the textbooks already there. When rewriting I’d neaten everything up, organise information into a better order, add more information from the textbook and improve my diagrams. 
  • Rewriting takes a lot of time and patience, so it’s not for everyone. I liked it for Biology though as it just solidified everything in my mind and a lot of it is words. 
  • If it’s not your thing, you could do online notes so you can edit them or you could use post it notes to edit it.
  • Free periods are also a good opportunity to study with others, I used them on occasion to work with my classmates.
  • It’s also a good time for getting extra help, if there’s anywhere you can get some sort of tutor or help free periods are the best time to go get this.

Generally/ At Home:

  • I used online flashcards to learn definitions and short facts. There’s lots of pre-prepared ones on memrise, but they do occasionally have annoying spellings. I got round this by making my own, which was good, if you have the time.
  • I also had physical flashcards, but I wrote summaries of the entire course when it got to exam time.
  • Another thing I did when it approached exam time is make lots of large posters with summaries of each area. 
  • Generally, I’d say the best method for revision at the end of the year is to summarise and cover everything. You need to know all the basics and be able to piece them all together as well. If you have a large breadth and depth of knowledge you can take on any of the questions.
  • When you get set tests during the terms, study hard, not only because it gives you predicted grades but also because that extra study/reminder of information helps you remember it better in the long term.
  • The other main idea is to repeat. That’s why I like rewriting my notes and doing summaries, repetition helps you to memorise. You can also make links as you look back and see why what you learnt before is relevant to this or how it links to what you’ve learnt since you were taught it.

I hope this helps! Good luck :)


Sufjan Stevens was born in Detroit, Michigan, and grew up in the chilly upper reaches of the Lower Peninsula. A self-taught musician, the young Sufjan pounded out elaborate Mozartian sonatas on a toy Casio, and by college became proficient on the oboe, recorder, banjo, guitar, vibraphone, bass, drums, piano, and other instruments too numerous to mention. Somewhere along the line he also started to sing, though at the time his friends didn’t encourage it. He bought a 4-track tape cassette recorder and painstakingly composed 90-minute concept albums for The Nine Planets, The 12 Apostles, and The Four Humors. He read William Blake, William Wordsworth, and William Faulkner. At that time, in college, the world loomed large and daunting, and Sufjan’s music came to sound like a medieval woodwind ensemble waving swords and torches at the twelve-headed dragon of death. During his last semester in college, Sufjan pruned, picked, and assembled a selection of these songs to produce the inaugural release “A Sun Came” on Asthmatic Kitty Records, a home label Sufjan initiated with his step-dad Lowell. A thousand copies were manufactured and shipped to a dark, dank closet somewhere in the vacuous black hole of the universe, where they shifted and snored in their sleep for several years to come.

Sufjan then moved to New York City and lived bohemian style, with three other college graduates, in the unfashionable financial district, commuting by bike to The New School for Social Research, where he was enrolled in the masters program for writers. There he met Jhumpa Lahiri, harassed Philip Gourevitch on the telephone, and tried unsuccessfully to complete an epic collection of stories and sketches about backwoods Midwestern kinsmen—Christian Fundamentalists, Amway salesmen, crystal healers— all set in a small rural town in Michigan. Hmmmm. No one seemed very interested. Sufjan went back to the 4-track, tired of “words, words, words,” and set out to complete his most ambitious project to date: a collection of programmatic, symphonic songs for the animals of the Chinese Zodiac. There were no lyrics, but more than a few cymbal swells, flourishes on the oboe, and ambient organ drones, all accompanied by computer-generated techno beats, and digital noise. The result was enterprising, but not quite flattering. He sent a few copies to press, which fell on confused ears. “…A hyper-modified Atari battling a souped-up Colecovision in a chess match/battle royal,” one writer noted. Feeling inspired, Sufjan dropped off a copy at New York’s favored record store, Other Music, only to find it in the used section, reduced price, two weeks later. Sufjan took this as a compliment. His label did not. Write songs, his step-dad insisted. Write something with words and melodies.

Sufjan went back to the books, mainly his own unwritten one. Taking bits and scraps of unfinished stories (character sketches, plot lines, penciled diagrams) Sufjan began to arrange his misshapen fiction into the bold mechanics of song, making friends with line breaks, meter, and rhyme scheme. These things led to melody, odd time signature, and a litany of jingle jangles on the drum kit, which had been taken out of storage once and for all. Here and there, on weekend trips, in quiet gasps of free time, Sufjan carried around his 8-track, recording songs in people’s homes, in cinderblock basements, in barn houses and rehearsal rooms. The vibraphone in Massachusetts, the electric organ in New Jersey, his sister’s husband’s grand piano, upstate Michigan. Word by word, note by note, everything came together like one great cosmic shuffle, the Big Bang. The result was a lushly orchestrated road trip through the backwoods of The Great Lake State, from motor-city to the winter beaches of Lake Superior. Now this is more like it! his step-dad said. This sounds pretty good! They decided to release it to the public, to act like a real record label. They found a distributor, a publicist, a booking agent, a make-up artist, a mime. Things were looking good. People lent an eager ear. The critics lowered their knives and their critical brow. Other Music put it in New Releases, top shelf! Europeans weren’t offended! Sufjan began to feel gallant and bold and confident about this great place called Planet Earth. This is just the beginning! he proclaimed over loudspeakers. This is just the tip of the iceberg! Galvanized by tourist brochures, road atlas maps, and the spirit of Walt Whitman, Sufjan began to intimate at other songs for other states, the American Dream, the national anthem, the continental rigmarole, the Delaware shuffle, Florida flamenco, California swing, all dramatized in song, the great epic symphony, in 50 movements, in 50 years! Lord help us!

Once the clang and clamor of patriotism subsided, Sufjan’s musical inquiry fell fast on the Land of Lincoln, stirred, perhaps, by sentimental recollections of his rebellious young adulthood on Clark Street in Chicago, Wrigleyville, the beachfront parks, the homeless kids with their pets, the abandoned school house, where he slept on a desk. During the winter of 2004, Sufjan spent four months in isolation, reading books and biographies, memorizing the unfashionable poems of Carl Sandburg, laughing and shuddering through Saul Bellow’s novels. He uncovered police blogs and books on tape. He solicited correspondence from old friends, Illinoisans once lost or estranged; he studied travel guides; he quizzed chat rooms; he made stuff up. All research, he decided, begins with your imagination and with your intuition, relying heavily on the convictions of the heart. During those long winter hand-clapping, piano-playing, drum-rolling months, Sufjan’s heart began to expand, leaving its fist-shaped mark on a series of songs that not so much pay homage to the Prairie State, but rack and rend its characters through potato farms, steel factories, street fairs, marching parades, convoluted rivers, and centuries past and present. The result was something bold, flashy, and ripe with advertisement, like the Goodyear blimp, but not without Sufjan’s tender rendering of the imagination. When all was said and done, Sufjan felt irrevocable changes taking place within his body, like a second puberty. His shoulders broadened, his mind quickened, his heart began to beat with quiet, patient thumps in a rhythm as fluid and faithful as the Chicago River.

And so on and so forth.

Sufjan’s other interests include graphic design, painting, running, knitting, crocheting, weaving, quilting, cleaning, photography, haircutting, and dry wall installation. He collects stamps and wheat pennies. He cooks legendary omelets and can whip up a sushi feast at the drop of a sake glass. In high school he played second string guard on a district champion basketball team and created his own language, now spoken by only two other people. His brother Marzuki is a nationally recognized marathon runner, elite status. His sister Djohariah has the most complicated, most whimsical, most monumental laugh in all of mankind.

random bios (masterpost)

© liamconfusd, like or reblog!
Credit automatic

  1. i’m not good for descriptions, sorry love
  2. now kiss you fool
  3. i’m the supreme
  4. pizza: i love you, i like you, i love, end
  5. same shit, but different day
  6. against Idiots
  7. let’s break up with your girlfriend
  8. enjoy the silence, idiot
  9. or you shut up, or I’ll break your face!!
  10. what are you doing here? get out
  11. sorry not sorry
  12. I like sucking
  13. boulevard of broken dreams
  14. i feel sad / i’m sad
  15. love does not exist, ok
  16. i don’t need you, i need wifi and lots of pizza
  17. i wanna be yours
  18. [friend’s voice] to speech that his crush
  19. black is not sad, black is life
  20. its easy for you, u’re pretty
  21. black is such a happy color, haha
  22. tomorrow will be a new day
  23. you are a hypocritical bitch
  24. we live in a tropical climate
  25. 100% princess
  26. fuck off… or fuck me…
  27. pink color? disgusting, ugh
  29. queen of disaster
  30. vodka + internet + food + music = happiness

(◕‿◕✿) (✿◠‿◠)  *∘✧* ღ ♥ ♡ ❤ ❥ △ ∞ ☆ ★ ✖ 。®™✤ ❝❞✥ ✦ ✧ ✩ ✫ ✬ ✭ ✮ ✯ ✰ ✱ ✲ ✳ ❃ ❂ ❁ ❀ ✿ ✾ ✽ ✼ ✻ ✺ ✹ ✸ ✷ ₪ ❃ ❂ ❁ ❀ ✿ ✾ ✽ ✼ ✻ ✺ ✹ ✸ ✷ ☢ ✌ ♔ ∆ ∇ ☾ ☽ ♡  ☼  ☁ ▲ ▼ (◡‿◡✿)  ☩ ☨ ☦ ✞ ✛ ✜ ✝  ✄ † ✞ ✝ ⇦ ⇧ ⇨ ⇩ ← ↑ → ↓ ➳  ➴ ➵ ➶ ➷ ➸ ➹ ☯ ♠ Ω ♤ ♣ ♧ ♥ ♡ ♦ ♢ ➀ ➁ ➂ ➃ ➄ ➅ ➆ ➇ ➈ ➉ ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓ ⊱✿◕‿◕✿⊰ ◑△◐ ◑▽◐ ☂ 《》 ▶◀



· sorry, i do not speak falsiânes
· me suga e mama
· eu vim enviada a este planeta para sofre
· pega no meu grelo e mama
· as vezes eu olho pro horizonte e penso ave maria nunca vo pode bja este teus labios
· feio que ta para,,,,, não pera
· bunda é igual a comida: vc gosta de receber mas não de dar
· que nude oq eu quero é comida coMIDA
· fofa cê usa cocôgate? pq só sai merda dessa tua boca
· vamo se bja ate a nossas bocas sangrarem
· que deus elimine sua alma
· eu estou so ferdo
· ado ado ado vai dar o cu seu viado
· vivo a filosofia do foda-se
· chupe um pau, talvez vc goste
· so la da di da di sua puta sai daqi
· eu não queria ser trouxa, but the hearts wants what it wants
· vapa put a keep are you
· bateu aquela famosa bad
· cala a boca já morreu, quem manda na minha boca é você, me bja
· inho inho inho meu pau no seu cuzinho
· bará bará bará berê berê berê vai tomar no cu e tbm se foder


· swimming away from your bullshit
· you are my ☀ my 🌙 and all my ⭐
· you are my only exception
· i’m in love with you
· be your own anchor
· when i kiss you i can taste the universe
· can’t go home alone again need someone to numb the pain
· can’t tell if i hate it or love it ohwell
· you are the reason for all my smiles, it makes me so happy without even knowing it
· you are my religion
· bitch, i know that i’m beautiful
· i could be your fantasy
· i only love it when you touch me, not feel me
· my soul will rest in your embrace

heeey amores, como vcs estão? bom, fiz essas bios pra comemorar os 300 seguidores do tumblr uhul 🎊🎉🎈 (eu sei isso parece meio idiota pra vcs mas pra mim é importante).
Então, like se usar ou credite na @pacificamren
Bjão, luv u 💖