mesenchymal

Mesenchymal stem cell. Coloured scanning electron micrograph (SEM) of a human mesenchymal stem cell (MSC). MSCs are multipotent stromal (connective tissue) cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), and adipocytes (fat cells). The youngest, most primitive MSCs can be obtained from the umbilical cord tissue. Magnification: x4500 when printed 10 centimetres wide.

Credit: STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY

Mesenchymal stem cells. Coloured scanning electron micrograph (SEM) of two human mesenchymal stem cells (MSCs). MSCs are multipotent stromal (connective tissue) cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), and adipocytes (fat cells). The youngest, most primitive MSCs can be obtained from the umbilical cord tissue. Magnification: x3000 when printed 10 centimetres wide.

Credit: STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY

Lung cell phenotype reverts when seeded onto decellularized lung matrix

(Mary Ann Liebert, Inc./Genetic Engineering News) Researchers seeded type II lung epithelial cells into a decellularized lung matrix to study their function and report the unexpected finding that instead of differentiating into type I lung cells, they instead transitioned to become mesenchymal cells, as would occur in wound healing. The design and results of this study and its implications for the development of protocols and cell culture environments to support the growth of functional lung tissue are presented in an article in Tissue Engineering, Part A.

from EurekAlert! - Technology, Engineering and Computer Science http://ffc.im/1EeEKac

Interactions between rat alveolar epithelial cells and bone marrow-derived mesenchymal stem cells: an in vitro co-culture model

All protocols involving animals were approved by the institutional animal care committee of Tokyo Medical and Dental University. Rat bone marrow-derived mesenchymal stem cells We obtained naïve BMSCs from adult male Sprague–Dawley rats (weight: 180–200 g) using a proce…
Source:Interactions between rat alveolar epithelial cells and bone marrow-derived mesenchymal stem cells: an in vitro co-culture model

Survival from rare bone cancer remains low

Ten-year survival of a rare malignancy called mesenchymal chondrosarcoma has been reported to be as low as 20 percent. But a new study has found survival is not as dismal as prior reports. More than half (51 percent) of patients survived at least five years, and 43 percent survived at least 10 years.

from Today’s Healthcare News – ScienceDaily http://ift.tt/1Ph3oT6


Survival from rare bone cancer remains low

Today’s Healthcare News – ScienceDaily

from HEALTH BUZZ http://ift.tt/1zYKIB4

Interactions between rat alveolar epithelial cells and bone marrow-derived mesenchymal stem cells: an in vitro co-culture model

All protocols involving animals were approved by the institutional animal care committee of Tokyo Medical and Dental University. Rat bone marrow-derived mesenchymal stem cells We obtained naïve BMSCs from adult male Sprague–Dawley rats (weight: 18…
Source: Interactions between rat alveolar epithelial cells and bone marrow-derived mesenchymal stem cells: an in vitro co-culture model

Personalized treatment strategies for non-small-cell lung cancer in Chinese patients: the role of crizotinib.

Personalized treatment strategies for non-small-cell lung cancer in Chinese patients: the role of crizotinib.

Onco Targets Ther. 2015;8:999-1007

Authors: Niu FY, Wu YL

Abstract
Anaplastic lymphoma kinase (ALK) rearrangement is an oncogene targeted with approved drugs second to epidermal growth factor receptor (EGFR) in lung cancer. Crizotinib was developed and introduced into clinical practice rapidly and successfully after the discovery of ALK rearrangement in non-small-cell lung cancer. Chinese and other Asian patients treated with crizotinib seem to have lower toxicity and higher efficacy compared with other ethnicities. Crizotinib showed potent antitumor activity and manageable toxicity in mesenchymal-epithelial transition factor (c-Met)/ROS1-positive non-small-cell lung cancer patients, but prospective clinical trials are still needed to confirm its efficacy and safety. Crizotinib appears to be effective against tumors originating from various organs that harbor ALK abnormalities. In the near future, we would classify the tumors by their genetic information beyond organs, such as ALKoma, EGFRoma, and RAFoma, and a single compound could be used for many different types of cancer in different organs. The major challenge of the widespread use of crizotinib in clinical practice is establishing convenient diagnostic techniques for the detection of ALK/c-Met/ROS1. In the present study, we reviewed the application of crizotinib in Chinese patients.

PMID: 25999733 [PubMed]



via pubmed: lymphoma daily http://ift.tt/1Hou8Ys
Continuous improvement after multiple mesenchymal adult stem cell transplantation in a patient with complete spinal cord injury.

See on Scoop.it - Adult Stem Cells Repair Body

Cell Transplant. 2015;24(4):661-72. doi: 10.3727/096368915X687796. Epub 2015 Mar 24.


EJ Morris’s insight:

More  scientific  documentation that  Adult Stem Cells are the body’s God created, God given, Regeneration and Repair Cells.  Adult Stem Cells WORK.  Adult Stem Cells Work Every Time !

See more Spinal Cord Injuries helped with Adult Stem Cells

http://www.adult-stemcells-blog.com/quadriplegic.html


See on ncbi.nlm.nih.gov

Mesenchymal Stem Cells (MSCs) Bone Marrow/Adipose, Both ADSCs and BMSCs, Adipose Derived Stromal Vascular Fraction (SVF), Autologous Fat Processing Via the Revolve System: Quality and Quantity of Fat Retention Evaluated in an Animal Model, Pre-Clinical Model: Design, Decant Method, Centrifugation Process, Fat Content Characterization, Pre-clinical Study Findings, Stromal Vascular Fraction Injections for Human Knee Osteoarthritis, Purpose Feasibility and Safety.