meningoencephalitis

/meningoencephalitis

My 4 year old dog inherited this. Its a fatal brain and spine disease and only a miracle can cure this. I’m truly heartbroken . I bought her in a pet shop and had no idea she came from a puppy mill or didn’t even know what a puppy mill was till now. a puppy mill is basically like a dog farm where they’re caged and made to breed and treated like shit so therefore they acquire trauma and a bunch of illnesses and diseases and their young ones eventually get this. Little by little she’s losing grasp of herself . It truly breaks my heart as I love my pets dearly. Uggggghhhhh.

New Post has been published on The Rakyat Post

New Post has been published on http://www.therakyatpost.com/news/2015/04/17/two-cases-of-brain-infection-disease-detected-at-army-camp-in-port-dickson/

Two cases of brain infection disease detected at army camp in Port Dickson

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KUALA LUMPUR, April 17, 2015:

The Health Ministry has detected two cases of meningoencephalitis – a brain infection – among the trainees at the Army Basic Training Centre (Pusasda) in Port Dickson, Negeri Sembilan.

The two trainees, who were room-mates, started their training together last month and both had reported similar symptoms which includes fever and muscle cramps.

They received early medical attention at the military hospital in the centre, but were later admitted into the Intensive Care Unit (ICU) at Port Dickson Hospital on April 14, 2015.

One of them, was then transferred to the ICU of Kuala Lumpur Hospital and both are now reported to be in stable condition.

“The health and medical team at the camp has taken prevention and control measures. Reportedly to date, 16 trainees, who were room-mates of the two patients, have been screened.

“Ten of them were found to have shown symptoms of fever, cough and headache. They were separated from the others and placed under quarantine in the centre, where they received outpatient medical care.

“We have obtained their clinical samples and have sent it to the National Public Health Laboratory (MKAK) in Sungai Buloh for further tests,” said the ministry in a statement today.

They stressed on the efforts carried out to identify the cause of the infection in the two trainees, along with the measures taken to stop further spread of the fatal disease.

Among those measures were disinfection activities involving the compounds around the affected area, daily health observation of all personnel and trainees there, and distribution of face mask to those at the centre.

According to the ministry’s webpage, meningoencephalitis is an inflammation that affects the brain and the membrane around it. The clinical symptoms include fever, headache, and nausea.

“It is generally caused by either bacterial, virus or maybe protozoa infection. It usually happens sporadically and carries the risk of clustered infection in places of high density such as an army camp, hostel or prison.

“It is for that reason that the risk of infection plaguing Pusasda affecting the general public is really low.

“The Ministry will continue to monitor the cluster incident and any developments regarding the case will be updated from time to time.”

The case came fresh after reports of two child deaths, one a 7-year-old and the other aged 11, believed to have died from hand, foot, and mouth disease (HFMD) and Influenza A (H1N1) respectively.

cdc.gov
Notes from the Field: Primary Amebic Meningoencephalitis Associated with Exposure to Swimming Pool Water Supplied by an Overland Pipe — Inyo County, California, 2015 | MMWR

Stay out of the pool, folks.

On June 17, 2015, a previously healthy woman aged 21 years went to an emergency department after onset of headache, nausea, and vomiting during the preceding 24 hours. Upon evaluation, she was vomiting profusely and had photophobia and nuchal rigidity. Analysis of cerebrospinal fluid was consistent with meningitis… . Her condition continued to decline, and she was transferred to a higher level of care in another facility on June 19, but died shortly thereafter.  … decedent’s only fresh water contact in the 2 weeks preceding illness onset was in a privately owned swimming pool in a desert environment on June 11 and 12. The pool had not been chemically treated until moments before swimming began, when an unknown amount of commercial liquid chlorine was added to the water as “shock” treatment.An environmental investigation of the swimming pool site on July 29 found that the source water for the pool was piped overland 1.5 miles from a mountain spring. The water temperature at the point where the spring water entered the pipe was 50°F (10°C) on the day of the site survey, with an ambient temperature of >100°F (>38°C) at 11 a.m.The overland transmission pipe had been installed in the 1960s. First, water cascaded down a canyon in a surface stream. For the last 1.5 miles before it entered the pool, the water was captured in a pipe. The top of the pipe was rusted out, having been compromised by root systems in many places, so that it essentially became a trough. Water temperature at the swimming pool entrance on the day of the site survey was 98°F (37°C),

26/11/2015 were a terrible day.. my dearest heart child got hospitalised with weird symptoms. I thought I was going to lose him, especially after the doctors told me they wasn’t sure if he would survive.
27/11/2015 they called me and told me it was critical and they couldn’t CT-scan him because they thought he wouldn’t wake up, so they really tried hard and instead took blood samples and what not.
28/11/2015 they called again. we finally found out what was wrong.
my poor baby had serious meningoencephalitis. I got him home later that day.

he recovered completely with antibiotics.
I’m so glad I got him home again, it was really terrible to watch him in that state, it went that bad in 4 hours only! today he is super healthy again, I’m so glad I didn’t lose him.

Intravascular clearance of disseminating Cryptococcus neoformans in the brain can be improved by enhancing neutrophil recruitment in mice

Extrapulmonary dissemination of Cryptococcus neoformans (C. neoformans) is one of the most critical steps in the development of meningoencephalitis. Here, we report that clearance of the disseminating C. neoformans occurs within the brain microvasculature. Interestingly, the efficiency of the intravascular clearance in the brain is reduced compared to that in the lung. Intravascular clearance is mainly mediated by neutrophils, and complement C5a receptor signaling is crucial for mediating neutrophil recruitment in the vasculature. C. neoformans-stimulated actin polymerization of neutrophils is critically involved in their recruitment to the lung, which is associated with the unique vascular structure detected in the lung. The relative lower efficiency of fungal clearance in the brain vasculature correlates with less efficient recruitment of neutrophils. Accordingly, intravascular clearance of C. neoformans in the brain could be remarkably improved by increasing the recruitment of neutrophils. We conclude that neutrophils have the ability to eliminate C. neoformans arrested in the vasculature. However, insufficient recruitment of neutrophils limited the optimal clearance of this microorganism in the brain. These results imply that a therapeutic strategy aimed at enhancing the accumulation of neutrophils could help prevent cryptococcal meningoencephalitis.

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Intravascular clearance of disseminating Cryptococcus neoformans in the brain can be improved by enhancing neutrophil recruitment in mice

Extrapulmonary dissemination of Cryptococcus neoformans (C. neoformans) is one of the most critical steps in the development of meningoencephalitis. Here, we report that clearance of the disseminating C. neoformans occurs within the brain microvasculature. Interestingly, the efficiency of the intravascular clearance in the brain is reduced compared to that in the lung. Intravascular clearance is mainly mediated by neutrophils, and complement C5a receptor signaling is crucial for mediating neutrophil recruitment in the vasculature. C. neoformans-stimulated actin polymerization of neutrophils is critically involved in their recruitment to the lung, which is associated with the unique vascular structure detected in the lung. The relative lower efficiency of fungal clearance in the brain vasculature correlates with less efficient recruitment of neutrophils. Accordingly, intravascular clearance of C. neoformans in the brain could be remarkably improved by increasing the recruitment of neutrophils. We conclude that neutrophils have the ability to eliminate C. neoformans arrested in the vasculature. However, insufficient recruitment of neutrophils limited the optimal clearance of this microorganism in the brain. These results imply that a therapeutic strategy aimed at enhancing the accumulation of neutrophils could help prevent cryptococcal meningoencephalitis.

This article is protected by copyright. All rights reserved

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