My 4 year old dog inherited this. Its a fatal brain and spine disease and only a miracle can cure this. I’m truly heartbroken . I bought her in a pet shop and had no idea she came from a puppy mill or didn’t even know what a puppy mill was till now. a puppy mill is basically like a dog farm where they’re caged and made to breed and treated like shit so therefore they acquire trauma and a bunch of illnesses and diseases and their young ones eventually get this. Little by little she’s losing grasp of herself . It truly breaks my heart as I love my pets dearly. Uggggghhhhh.

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Two cases of brain infection disease detected at army camp in Port Dickson

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KUALA LUMPUR, April 17, 2015:

The Health Ministry has detected two cases of meningoencephalitis – a brain infection – among the trainees at the Army Basic Training Centre (Pusasda) in Port Dickson, Negeri Sembilan.

The two trainees, who were room-mates, started their training together last month and both had reported similar symptoms which includes fever and muscle cramps.

They received early medical attention at the military hospital in the centre, but were later admitted into the Intensive Care Unit (ICU) at Port Dickson Hospital on April 14, 2015.

One of them, was then transferred to the ICU of Kuala Lumpur Hospital and both are now reported to be in stable condition.

“The health and medical team at the camp has taken prevention and control measures. Reportedly to date, 16 trainees, who were room-mates of the two patients, have been screened.

“Ten of them were found to have shown symptoms of fever, cough and headache. They were separated from the others and placed under quarantine in the centre, where they received outpatient medical care.

“We have obtained their clinical samples and have sent it to the National Public Health Laboratory (MKAK) in Sungai Buloh for further tests,” said the ministry in a statement today.

They stressed on the efforts carried out to identify the cause of the infection in the two trainees, along with the measures taken to stop further spread of the fatal disease.

Among those measures were disinfection activities involving the compounds around the affected area, daily health observation of all personnel and trainees there, and distribution of face mask to those at the centre.

According to the ministry’s webpage, meningoencephalitis is an inflammation that affects the brain and the membrane around it. The clinical symptoms include fever, headache, and nausea.

“It is generally caused by either bacterial, virus or maybe protozoa infection. It usually happens sporadically and carries the risk of clustered infection in places of high density such as an army camp, hostel or prison.

“It is for that reason that the risk of infection plaguing Pusasda affecting the general public is really low.

“The Ministry will continue to monitor the cluster incident and any developments regarding the case will be updated from time to time.”

The case came fresh after reports of two child deaths, one a 7-year-old and the other aged 11, believed to have died from hand, foot, and mouth disease (HFMD) and Influenza A (H1N1) respectively.

Meningoencephalitis with microinfarcts in early neuroborreliosis.

PubMed: Meningoencephalitis with microinfarcts in early neuroborreliosis.

Neuroradiology. 2016 Feb 9;

Authors: Huys AM, Lalive PH, Haller S

PMID: 26861491 [PubMed - as supplied by publisher]

PubMed: Diagnosing Balamuthia mandrillaris Encephalitis With Metagenomic Deep Sequencing.: Related Articles

Diagnosing Balamuthia mandrillaris Encephalitis With Metagenomic Deep Sequencing.

Ann Neurol. 2015 Nov;78(5):722-30

Authors: Wilson MR, Shanbhag NM, Reid MJ, Singhal NS, Gelfand JM, Sample HA, Benkli B, O'Donovan BD, Ali IK, Keating MK, Dunnebacke TH, Wood MD, Bollen A, DeRisi JL

OBJECTIVE: Identification of a particular cause of meningoencephalitis can be challenging owing to the myriad bacteria, viruses, fungi, and parasites that can produce overlapping clinical phenotypes, frequently delaying diagnosis and therapy. Metagenomic deep sequencing (MDS) approaches to infectious disease diagnostics are known for their ability to identify unusual or novel viruses and thus are well suited for investigating possible etiologies of meningoencephalitis.
METHODS: We present the case of a 74-year-old woman with endophthalmitis followed by meningoencephalitis. MDS of her cerebrospinal fluid (CSF) was performed to identify an infectious agent.
RESULTS: Sequences aligning to Balamuthia mandrillaris ribosomal RNA genes were identified in the CSF by MDS. Polymerase chain reaction subsequently confirmed the presence of B. mandrillaris in CSF, brain tissue, and vitreous fluid from the patient’s infected eye. B. mandrillaris serology and immunohistochemistry for free-living amoebas on the brain biopsy tissue were positive.
INTERPRETATION: The diagnosis was made using MDS after the patient had been hospitalized for several weeks and subjected to costly and invasive testing. MDS is a powerful diagnostic tool with the potential for rapid and unbiased pathogen identification leading to early therapeutic targeting.

PMID: 26290222 [PubMed - indexed for MEDLINE]

[Successful treatment for cryptococcal meningoencephalitis complicated by cerebral salt-wasting syndrome in a patient with chronic lymphocytic leukemia: A clinical case].

[Successful treatment for cryptococcal meningoencephalitis complicated by cerebral salt-wasting syndrome in a patient with chronic lymphocytic leukemia: A clinical case].

Ter Arkh. 2015;87(11):99-102

Authors: Potapenko VG, Konovalenko IB, Oksema EV, Filippova LN, Dulaeva EN, Derevyannykh NA, Krasnoruzhsky AI, Klimovich AV, Klimko NN, Medvedeva NV

Cryptococcus neoformans is a common agent of fungal meningoencephalitis in immunocompromised patients. Cerebral salt-wasting syndrome is one of the rare causes of severe hyponatremia in patients with CNS diseases. The paper describes the first clinical case of a patient, whose onset of chronic lymphocytic leukemia was complicated by cryptococcal meningoencephalitis presenting with mental disorders and severe electrolytic imbalance. Antifungal treatment with amphotericin B and fluconazole could alleviate an infectious process and metabolic disturbances.

PMID: 26821425 [PubMed - in process]

via pubmed: cllsllupdate1