I think the most underrated bit of genius in 17776 is the overlap with real life items. Items, not really places or people. So far all of them have been related to the main themes of 17776 in some way:
Bee States Ballroom: doing busy work because not only can you afford to do pointless work, it’s the only thing you CAN do in your current situation
Livermore Bulb: eternal but meaningless life
Koy Detmer balls: arbitrarily enforced scarcity and conflict for pure entertainment value. also football
The fact that this much information is being expressed through objects goes in line with what Nine said about humans becoming machine-like. In their quest for entertainment and meaning, humans have centered their entire lives around things that would normally be incredibly boring and worthless.
Every human we’ve met has been totally dedicated to whatever game they’re playing and all of its bizarre conditions. Nobody does anything for the hell of it anymore, they need something concrete to work towards, no matter how stupid it is. Sure, there are mentions of people that don’t play football, but even these people are completely sunk into their daily routines and a sense of constancy.
The most human beings in 17776 are machines millions of miles from Earth. They deal with immortality well because they were always supposed to be immortal.