Lamellipodia are not the only way for cells to get about— plasma membrane blebs can also drive cell migration. Once thought to be restricted to dying cells, these spherical membrane protrusions are now thought to be particularly important in tumor cells, which have been shown to switch between the lamellipodia- and bleb-based motility.
Image: Cells from culture were imaged with a JEOL 6700 Field Emission Scanning Electron Microscope, and then false colored with Adobe Photoshop. By Anne Weston, Cancer Research UK. (Cell.com)