The story begins in the dystopian capital city of an insignificant planet in a human-dominated galactic empire. (The Bergs, aliens who resemble featherless birds and reside in a neighboring galaxy, make up another power bloc.) DiFool receives the Light Incal, a crystal of enormous powers, from a dying Berg. The Incal is then sought by many factions: the Bergs; the corrupt and decadent government of the great pit-city; the rebel group Amok; and the Church of Industrial Saints (commonly referred to as the Techno-Technos or the Technopriests), a sinister technocratic cult which worships the Dark Incal. Animah (an allusion to anima), the keeper of the Light Incal, seeks it as well.
The series mixes space opera, metaphysics, and satire; a counterpoint to the grandiosity of the events is always Difool’s base, even cowardly nature.