invasive growth

This top turns see-through if you leave personal data exposed

Clothing reveals how much wearer is revealing.

by Liat Clark, wired.co.uk June 17 2014, 9:45am CST

A Brooklyn-based designer has created a 3D-printed sculptural boob tube to spark social commentary on the state of privacy in a data-driven world—by making the top gradually more sheer.

X.pose’s striking black webbed rubber structure was engineered using a Stratasys printer, molded to the body to ensure comfort and very much inspired by creator Xuedi Chen’s previous work, Invasive Growth (moss-grown jewelry based on the parasitic cordyceps fungus). But underneath, its layers tell another story about our lack of control and veritable vulnerability when it comes to who uses our data, what for, and how much they take.

This story originally appeared on Wired UK.

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miR-708/LSD1 axis regulates the proliferation and invasion of breast cancer cells.

PubMed: Related Articles

miR-708/LSD1 axis regulates the proliferation and invasion of breast cancer cells.

Cancer Med. 2016 Feb 2;

Authors: Ma L, Ma S, Zhao G, Yang L, Zhang P, Yi Q, Cheng S

Abstract
Breast cancer is one of the most common malignant tumors in women worldwide. The microRNAs (miRNAs) are small, noncoding RNAs that regulate various biological processes, including breast cancer. miR-708 played an important role in a variety of cancers. However, its involvement in breast cancer remains largely unclear. In this study, we found that forced the expression of miR-708 in breast cancer cell lines decreased cell proliferation and invasion, whereas inhibition of miR-708 increased cell growth and invasion. miR-708 could directly target the LSD1 3'UTR to downregulate the expression. Further studies suggested that inhibition of LSD1 could phenocopied function of the miR-708 overexpression in MDA-MB-231 cells .Overexpression of LSD1 could counteract the effects of miR-708 on the proliferation and invasion. Taken together, the results indicate that miR-708 may function as a tumor suppressor gene in breast cancer development, and miR-708/LSD1 axis may be a therapeutic intervention in breast cancer in the future.

PMID: 26833707 [PubMed - as supplied by publisher] http://dlvr.it/KPmqSP

TE Connectivity Acquires Creganna Medical Group For $895 Million

Shares of TE Connectivity Ltd (NYSE: TEL) were trading lower by nearly 4 percent on Tuesday following the company’s announcement that it has agreed to acquire Creganna Medical group for $895 million.

Creganna Medial is a designer and manufacturer of minimally invasive delivery and access devices. The company reported sales of approximately $250 million in 2015.

TE Connectivity noted that the acquisition strengthens its global leadership position, establishes itself as a leading provider of minimally invasive integrated solutions and also complements its already existing product portfolio by offering customers an unmatched set of integrated solutions.

“The acquisition of Creganna Medical is part of our well-established strategy to expand our leadership position in harsh environment applications,” said TE Connectivity Chairman and CEO Tom Lynch. “This transaction builds on our AdvancedCath acquisition and establishes TE as a leading supplier to the high-growth minimally invasive interventional segment. Our existing medical product offering, coupled with these acquisitions, positions TE with the broadest range of products and technologies serving this high-growth space.

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© 2016 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

TE Connectivity picks up Creganna Medical for $895m

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TE Connectivity (NYSE:TEL) said today that it agreed to pick up Irish medical device maker Creganna Medical for $895 million in cash.

Cregganna, which is owned by private equity shop Permira Funds, posted sales of $250 million last year, Schaffhausen, Switzerland-based TE Connectivity said.

“The acquisition of Creganna Medical is part of our well-established strategy to expand our leadership position in harsh environment applications,” chairman & CEO Tom Lynch said in prepared remarks. “This transaction builds on our AdvancedCath acquisition and establishes TE as a leading supplier to the high-growth minimally invasive interventional segment. Our existing medical product offering, coupled with these acquisitions, positions TE with the broadest range of products and technologies serving this high-growth space.

“We look forward to welcoming Creganna’s talented team to TE,” Lynch said. “The combined team will bring significant engineering expertise and industry depth to create highly engineered solutions for OEMs globally.”

TE Connectivity said it expects the deal to add 3¢ to its adjusted earnings per share in the 1st year after the deal closes, which is expected to occur during the 3rd quarter.

The post TE Connectivity picks up Creganna Medical for $895m appeared first on MassDevice.



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Frustration grows as armed Oregon standoff continues

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Business

Frustration grows as armed Oregon standoff continues

The group took over the Malheur National Wildlife Refuge on Jan. 2 after a peaceful protest in nearby Burns, Oregon, over the conviction of two local ranchers on arson charges. Dwight Hammond, 73, and his son Steven Hammond, 46, said they lit fires on federal land in 2001 and 2006 to reduce the growth of invasive plants and protect their property from wildfires. The two were convicted three years ago and served time — the father three months, the son one year.

Increasingly Bundy has called for federal lands to be turned over to local authorities and has urged ranchers to renounce their federal grazing contracts. Bundy has said they plan to open the 300-square mile Oregon refuge to cattle this spring.

grave concerns regarding the present handling of the occupation as well as the prosecution of the militants.

Charlotte Rodrique

Inhibitor of growth-4 is a potential target for cancer therapy

Abstract

The inhibitor of growth-4 (ING-4) belongs to the inhibitor of growth (ING) family that is a type II tumor suppressor gene including five members (ING1-5). As a tumor suppressor, ING4 inhibits tumor growth, invasion, and metastasis by multiple signaling pathways. In addition to that, ING4 can facilitate cancer cell sensitivity to chemotherapy and radiotherapy. Although ING4 loss is observed for many types of cancers, increasing evidences show that ING4 can be used for gene therapy. In this review, the recent progress of ING4 regulating tumorigenesis is discussed.

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