A First-of-Its-Kind HIV Vaccine Will Move to Phase II Trials in 2017
This is progress.
A brand new type of HIV vaccine will move onto phase II clinical trials in 2017, after phase I trials showed that it was safe to use in humans.
The potential new vaccine will be tested on 600 people in North America, to see how well it can prevent them from getting the virus.
Before we get too excited, the phase I trials were only set up to show that the vaccine was tolerated well by the human body - they didn’t demonstrate if it actually works as a preventative treatment.
But the team saw promising results, with the vaccine triggering an immune response in the HIV-positive patients it was tested on.
“We were very excited with the phase I results,” said team leader Chil-Yong Kang, from Western University in Canada.
“The trial demonstrated that our vaccine stimulates broadly neutralising antibodies that will neutralise not only single sub-types of HIV, but other sub-types, which means that you can have the vaccine cover many different strains of the virus.”
The results of that trial have been published this week in the journal Retrovirology, and the researchers have announced that they’ve received regulatory approval to take the vaccine development to the next level as early as September next year.