herpesvirus

Porcine Respiratory - NAVLE Review #4

Originally posted by dailypiggie

Most common respiratory diseases of Pigs:

Piglets/ Weanlings:

Bacterial:

  • Mycoplasma hyopneumoniae: Pneumonia; 3-10 wk old piglets
  • Mycoplasma hyorhinus: Pericarditis, Pleuritis, Peritonitis, Arthritis (all the -itis); 3-10 wk old piglets
  • Pasterurella multocida: Fibrinous pneumonia; seen in association with other diseases (Mycoplasma, APP, SIV)

Viral:

  • Porcine Reproductive and Respiratory Syndrome Virus (PRRSV): Arterivirus: Focal to diffuse interstitial pneumonia, can progress to bronchopneumonia. 
  • Psudorabies (Herpesvirus): CNS signs in neonates (& sudden death). Piglets > 3 weeks sneezing, coughing, necrotic bronchitis, bronchiolitis, alveolitis. 
  • Porcine Circovirus Virus - 2: Pneumonia, commonly seen as a complex with PMWS. 

Originally posted by 8bitcookies

Grow-Finish Pigs:

Bacterial:

Actinobacillus pleuropneumoniae (APP): Pneumonia; Acute death

Atrophic Rhinitis (Bordetella bronchiseptica (+/-) Pasterella multocida): Variable turbinate atrophy, secondary pneumonia. Pigs > 8 weeks. 

Viral:

Swine Influenza (SIV): high morbidity, low mortality- nasal discharge, coughing. All age groups. 

2

Cancer-fighting viruses win approval

An engineered herpesvirus that provokes an immune response against cancer has become the first treatment of its kind to be approved for use in the United States, paving the way for a long-awaited class of therapies. On 27 October, the US Food and Drug Administration (FDA) approved a genetically engineered virus called talimogene laherparepvec (T-VEC) to treat advanced melanoma. Four days earlier, advisers to the European Medicines Agency had endorsed the drug.

With dozens of ongoing clinical trials of similar ‘oncolytic’ viruses, researchers hope that the approval will generate the enthusiasm and cash needed to spur further development of the approach. “The era of the oncolytic virus is probably here,” says Stephen Russell, a cancer researcher and haematologist at the Mayo Clinic in Rochester, Minnesota. “I expect to see a great deal happening over the next few years.”

Nature 526, 622–623 (29 October 2015) doi:10.1038/526622a

Killer T cells (orange) are recruited to attack malignant cells (mauve) in the viral-based cancer therapy T-VEC. Dr. Andrejs Liepins/SPL

anonymous asked:

No wonder alfie has an eye ulcer. You guys have all those fucking scented candles, are you delusional? Those are known to cause eye problems in cats. You should know better. Especially you Kaelyn.

I didn’t realize you were a Vet anonymous -  Feel free to leave published journal article (JAVMA, JAVECCS, JAVIM) supporting your scientifically proven statement.  Alfie, who has tested positive via PCR for Herpesvirus (like most cats in the world), is prone to herpesviral conjunctivitis, which in this case lead to a superficial corneal ulcer.  I am more than happy to read into your opinion if you can provide scientific published, peer-reviewed journal articles supporting it.  Will be looking forward to your response.