herpesvirus

jailedwords  asked:

Dottore quali sono le conseguenze a cui si può andare incontro con la cura omeopatica di una varicella? Il mio amico dice che la figlia è guarita. Ma cosa ha rischiato? Cosa rischia in futuro? Loro non credono al potere dei vaccini. Grazie.

Beh, omeopatica o allopatica, la cura per un’infezione da Herpesvirus umano 3 non esiste… una volta che lo contrai, esistono farmaci sintomatici (antipiretici, antistaminici) che però non influenzano minimamente il decorso della malattia.

Di tutte le malattie esantematiche ‘vaccinabili’ è forse quella gravata da minori effetti collaterali per gli adolescenti sani ma esistono dei rischi tangibili per i neonati e per gli adulti, soprattutto anziani.

Per i neonati sicuramente polmonite, otite ed encefalite (soprattutto se associate ad altre patologie respiratorie) e negli adulti insufficienza respiratoria, infezioni cutanee e tutta la sequela non piccola dell’Herpes Zoster (Fuoco di S.Antonio).

Direi che il vaccino continua a rimanere la scelta migliore.

Porcine Respiratory - NAVLE Review #4

Originally posted by dailypiggie

Most common respiratory diseases of Pigs:

Piglets/ Weanlings:

Bacterial:

  • Mycoplasma hyopneumoniae: Pneumonia; 3-10 wk old piglets
  • Mycoplasma hyorhinus: Pericarditis, Pleuritis, Peritonitis, Arthritis (all the -itis); 3-10 wk old piglets
  • Pasterurella multocida: Fibrinous pneumonia; seen in association with other diseases (Mycoplasma, APP, SIV)

Viral:

  • Porcine Reproductive and Respiratory Syndrome Virus (PRRSV): Arterivirus: Focal to diffuse interstitial pneumonia, can progress to bronchopneumonia. 
  • Psudorabies (Herpesvirus): CNS signs in neonates (& sudden death). Piglets > 3 weeks sneezing, coughing, necrotic bronchitis, bronchiolitis, alveolitis. 
  • Porcine Circovirus Virus - 2: Pneumonia, commonly seen as a complex with PMWS. 

Originally posted by 8bitcookies

Grow-Finish Pigs:

Bacterial:

Actinobacillus pleuropneumoniae (APP): Pneumonia; Acute death

Atrophic Rhinitis (Bordetella bronchiseptica (+/-) Pasterella multocida): Variable turbinate atrophy, secondary pneumonia. Pigs > 8 weeks. 

Viral:

Swine Influenza (SIV): high morbidity, low mortality- nasal discharge, coughing. All age groups. 

anonymous asked:

I know you probably have a lot on your plate so I'm sorry in advance, but I was wondering about vaccines as I was reading your vaccine tag as well as reading this other blog/webpage on cat vaccinations. I trust your opinion more so I was wondering how serious are adjuvants wrt sarcomas? You mentioned that feline Leuk vaccine is more strongly associated with ISS. I was also wondering if there was actually a correlation between vaccinations and nephritis?

I practice veterinary medicine in Australia, and our vaccination protocols are a bit different to the USA and most of the rest of the world. In particular, we don’t have rabies.

The vaccines for cats that are in common use here are:

  • F3 (calicivirus, herpesvirus and panleukopenia)
  • F4 (same as F3 plus chlamydia)
  • FIV (Feline Immunodeficiency Virus)
  • FeLV (Feline Leukemia Virus)

With rabies vaccines only being used for export.

Most cats get at least an F3 or an F4, and annual vaccination is recommended most of the time, because the herpesvirus component doesn’t seem to grant immunity for much more than 12 months. Outdoor or indoor/outdoor cats often, but not always because humans are slack, get FIV vaccinations. FeLV vaccines are not in common use, and are mostly used in high stress situations (eg breeding catteries) or in the face of an outbreak.

So most of our feline vaccinations are F3, F4 and FIV.

I’ve seen one Injection Site Sarcoma (ISS) in seven years of practice. It was in a 3 year old purebred cat, so he hadn’t had that many cumulative injections in his life, but he did get FIV vaccines. I suspect he was unlucky.

It’s also worth noting that in Australia, the general public is a bit on the slack side with bringing their cats in for annual vaccinations. Most cats get their kitten doses, and maybe an adult booster for the first two or three years, and then are ‘forgotten’ to bring in to he vet unless there is a problem or they’re dying.

Rabies vaccine seems to have a stronger association with ISS. Whether this is because people are more diligent about their rabies vaccine, or whether it’s an adjuvant issue, I’m not in a position to speculate.

There is also a stronger association between the retroviral vaccines (FIV and FeLV) and ISS. Whether it’s because these killed vaccines have different adjuvants, or whether it’s an intrinsic property of the retroviruses, I don’t know. But the association is there.

But it is worth noting that Injection Site Sarcomas can result from any injection, as they all cause some tissue trauma.

So how much of a risk is it? Well, the last conference I went to presented data that put the odds of a cat developing ISS with annual vaccination at around 1 in 10,000 to 1 in 100,000.

Now, that’s not a huge risk, though the consequences of developing ISS are severe. However it’s relative risk that we consider.

The Relative Risk of my cats, in Australia, developing rabies infection is zero. The risk of them developing ISS from rabies vaccination is very small, but it is higher than zero, and so we do not vaccinate for rabies. If we were in a rabies endemic country then you can bet your happy little backside that we would vaccinate for rabies, because the risks of potential rabies infection far exceed the risk of ISS.

The Relative Risk of my cat Wonka contracting FIV through a bite or a fight was extremely small when he was an only cat with a strictly indoor lifestyle.

Once we had Bael living with us, who was lovely but FIV positive, the Relative Risk of Wonka contracting FIV became much higher, certainly higher than a 1 in 10,000 chance, and so he was vaccinated for FIV.

I am aware of this risk, but I choose to do it anyway in this context.

I do routinely administer FIV vaccines over the right scapula though. My reasoning being that if a patient does develop an ISS, then at least there’s a solid barrier in the scapula to hopefully prevent it going deeper, which improves the odds of removing it in only one surgery without removing ribs.

I know an immunologist that vaccinated his cats in the tail tip, so that if they do develop an ISS he will just amputate the tail. He knows this is probably excessively paranoid, but when you’re exposed to all that data all the time, it makes you worry. I haven’t figured out how to do this easily yet.

I don’t think there’s a particular increase with nephritis and regular vaccinations. Excessive immune complexes can damage kidneys, but that’s generally fairly severe and shouldn’t be happening with a vaccination, more likely a bacterial or immune mediated condition. And skipping twelve years of vaccines certainly doesn’t protect cats from kidney disease.

2

Cancer-fighting viruses win approval

An engineered herpesvirus that provokes an immune response against cancer has become the first treatment of its kind to be approved for use in the United States, paving the way for a long-awaited class of therapies. On 27 October, the US Food and Drug Administration (FDA) approved a genetically engineered virus called talimogene laherparepvec (T-VEC) to treat advanced melanoma. Four days earlier, advisers to the European Medicines Agency had endorsed the drug.

With dozens of ongoing clinical trials of similar ‘oncolytic’ viruses, researchers hope that the approval will generate the enthusiasm and cash needed to spur further development of the approach. “The era of the oncolytic virus is probably here,” says Stephen Russell, a cancer researcher and haematologist at the Mayo Clinic in Rochester, Minnesota. “I expect to see a great deal happening over the next few years.”

Nature 526, 622–623 (29 October 2015) doi:10.1038/526622a

Killer T cells (orange) are recruited to attack malignant cells (mauve) in the viral-based cancer therapy T-VEC. Dr. Andrejs Liepins/SPL

anonymous asked:

No wonder alfie has an eye ulcer. You guys have all those fucking scented candles, are you delusional? Those are known to cause eye problems in cats. You should know better. Especially you Kaelyn.

I didn’t realize you were a Vet anonymous -  Feel free to leave published journal article (JAVMA, JAVECCS, JAVIM) supporting your scientifically proven statement.  Alfie, who has tested positive via PCR for Herpesvirus (like most cats in the world), is prone to herpesviral conjunctivitis, which in this case lead to a superficial corneal ulcer.  I am more than happy to read into your opinion if you can provide scientific published, peer-reviewed journal articles supporting it.  Will be looking forward to your response.