harmful algal blooms

Five Ways the International Space Station’s National Lab Enables Commercial Research

A growing number of commercial partners use the International Space Station National Lab. With that growth, we will see more discoveries in fundamental and applied research that could improve life on the ground.

Space Station astronaut Kate Rubins was the first person to sequence DNA in microgravity.

Since 2011, when we engaged the Center for the Advancement of Science in Space (CASIS) to manage the International Space Station (ISS) National Lab, CASIS has partnered with academic researchers, other government organizations, startups and major commercial companies to take advantage of the unique microgravity lab. Today, more than 50 percent of CASIS’ experiments on the station represent commercial research.

Here’s a look at five ways the ISS National Lab is enabling new opportunities for commercial research in space.

1. Supporting Commercial Life Sciences Research

One of the main areas of focus for us in the early origins of the space station program was life sciences, and it is still a major priority today. Studying the effects of microgravity on astronauts provides insight into human physiology, and how it evolves or erodes in space. CASIS took this knowledge and began robust outreach to the pharmaceutical community, which could now take advantage of the microgravity environment on the ISS National Lab to develop and enhance therapies for patients on Earth. Companies such as Merck, Eli Lilly & Company, and Novartis have sent several experiments to the station, including investigations aimed at studying diseases such as osteoporosis, and examining ways to enhance drug tablets for increased potency to help patients on Earth. These companies are trailblazers for many other life science companies that are looking at how the ISS National Lab can advance their research efforts.

2. Enabling Commercial Investigations in Material and Physical Sciences

Over the past few years, CASIS and the ISS National Lab also have seen a major push toward material and physical sciences research by companies interested in enhancing their products for consumers. Examples range from Proctor and Gamble’s investigation aimed at increasing the longevity of daily household products, to Milliken’s flame-retardant textile investigation to improve protective clothing for individuals in harm’s way, and companies looking to enhance materials for household appliances. Additionally, CASIS has been working with a variety of companies to improve remote sensing capabilities in order to better monitor our oceans, predict harmful algal blooms, and ultimately, to better understand our planet from a vantage point roughly 250 miles above Earth.

3. Supporting Startup Companies Interested in Microgravity Research 

CASIS has funded a variety of investigations with small startup companies (in particular through seed funding and grant funding from partnerships and funded solicitations) to leverage the ISS National Lab for both research and test-validation model experiments. CASIS and The Boeing Company recently partnered with MassChallenge, the largest startup accelerator in the world, to fund three startup companies to conduct microgravity research.

4. Enabling Validation of Low-Earth Orbit Business Models 

The ISS National Lab helps validate low-Earth orbit business models. Companies such as NanoRacks, Space Tango, Made In Space, Techshot, and Controlled Dynamics either have been funded by CASIS or have sent instruments to the ISS National Lab that the research community can use, and that open new channels for inquiry. This has allowed the companies that operate these facilities to validate their business models, while also building for the future beyond station.

5. Demonstrating the Commercial Value of Space-based Research

We have been a key partner in working with CASIS to demonstrate to American businesses the value of conducting research in space. Through outreach events such as our Destination Station, where representatives from the International Space Station Program Science Office and CASIS select cities with several major companies and meet with the companies to discuss how they could benefit from space-based research. Over the past few years, this outreach has proven to be a terrific example of building awareness on the benefits of microgravity research.

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theguardian.com
Meat industry blamed for largest-ever 'dead zone' in Gulf of Mexico
A new report shows toxins from suppliers to companies like Tyson Foods are pouring into waterways, causing marine life to leave or die.
By Oliver Milman

The global meat industry, already implicated in driving global warming and deforestation, has now been blamed for fueling what is expected to be the worst “dead zone” on record in the Gulf of Mexico.

Toxins from manure and fertilizer pouring into waterways are exacerbating huge, harmful algal blooms that create oxygen-deprived stretches of the gulf, the Great Lakes and Chesapeake Bay.

Meat Is murder for animals, the environment, your health - mind, body, & soul.

Eutrophication

Eutrophication is when there are too many nutrients released into the water system.  The opposite of that is oligotrophication, or nutrient poor.

Coral: grows in oligotrophic waters.  DIES by being overgrown by algae (which thrive in eutrophic waters), which aren’t controlled by overfishing herbivores (small fishes and urchins).

Contributions to Eutrophication:  

  • Agriculture/Aquaculture: releases a high amount of ammonia (N2 + H2 = ammonia) from fertilizers and CAFOs (Concentrated Animal Feeding Operations) –> cheap/subsidized! –> enters coastal waters
  • Hurricanes: destruction of waste holders in CAFOs, ex. Hurricane Floyd

Results of Eutrophication:

  • Harmful Algal Blooms (HAB): Red tides–> have toxins, creates anoxic zones –> INCREASING
  • Toxins: bioaccumulation, infected shellfish –> paralysis, neurotoxins, diarrhetic, amnesiac/domoic acid poisonings
  • Anoxic zones: kills fish, shellfish, whales, seabirds, manatees, humans –> spring/summer because of increased light, warmer watter, strong waters (little mixing), decaying/accumulation of organic matter, and ecosystem loading –> Mostly affects: benthic organisms (can’t migrate), Demersal (benthic) fisheries (loss of habitat/prey), long-term ecosystem effects

Examples of Eutrophic Systems:

  • Chesapeake Bay: Largest/best studied US estuary, degraded system –> psychocline (increased density) of nutrients
  • Gulf of Mexico Dead Zone: Almost no O2, heavy plankton decay

Prevention of Eutrophication:

  • Elimination of Point Source Pollution –> Farms (regulation, cooperative efforts between states/nations)
  • Elimination/Reduction of Non-Point Source Polution –> phosphate-free soaps, over fertilization, treatment of waste water, over consumption
  • Prevent Overharvesting of Filter Feeders

LARGEST BALEEN WHALE MASS STRANDING IN SOUTHERN CHILE RELATED TO TOXIC ALGAL BLOOM

In March 2015, by far the largest reported mass mortality of baleen whales took place in a gulf in Southern Chile. At that moment, researchers discovered 367 dead whales, from the sector of Gulf of Penas and Puerto Natales, in Magallanes region.  

In May the scientific journal PeerJ published the final study on the mass stranding event, most of them sei whale (Balaenoptera boreal), whale species which is endangered. According to the research, led by Vreni Häussermann, the event was related to the proliferation of toxic algae during the El Niño phenomenon.

While large mass mortality events are well known for toothed whales, they have been rare in baleen whales due to their less gregarious behavior. Although in most cases the cause of mortality has not been conclusively identified, some baleen whale mortality events have been linked to bio-oceanographic conditions 

According to the study if the frequency and magnitude of mass mortality events increase due to climate change this would have a significant impact on the local population and threaten the recovery of this endangered species, which in the Southern Hemisphere was reduced by whaling from about 100,000 to 24,000 individuals by 1980.

  • Photo: SERNAPESCA
  • Reference:  Häussermann et al. 2017. Largest baleen whale mass mortality during strong El Niño event is likely related to harmful toxic algal bloom. PeerJ
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Red Tides

Red tides, a common term for the more proper name of “harmful algal blooms” (HABs), occur when colonies of algae—simple ocean plants that live in the sea—grow out of control while producing toxic or harmful effects on people, fish, shellfish, marine mammals and birds. The human illnesses caused by HABs, though rare, can be debilitating or even fatal. As the name suggests, the bloom of algae often turns the water red.

But not all algal blooms are harmful. Most blooms, in fact, are beneficial because the tiny plants are food for animals in the ocean. In fact, they are the major source of energy that fuels the ocean food web.

15 Ways the International Space Station is Benefiting Earth

With astronauts living and working aboard the International Space Station, we’re learning a great deal about creating and testing critical systems, maintaining efficient communications and protecting the human body during a deep space mission. While these are critical to our journey to Mars, it is important to also note all the ways in which research conducted and technology tested aboard the orbiting laboratory help us here on Earth.

Here are 15 ways the space station is benefiting life on Earth:

1. Commercializing Low-Earth Orbit

An exciting new commercial pathway is revolutionizing and opening access to space, fostering America’s new space economy in low-Earth orbit. For the first time, the market is expressing what research can and should be done aboard the microgravity laboratory without direct government funding. Our move to purchase commercial cargo resupply and crew transportation to the space station enables U.S. businesses to develop a competitive capability they also can sell as a service to others while freeing our resources for deep space exploration. Private sector participation provides a new model for moving forward in partnership with the government.

2. Supporting Water Purification Efforts Worldwide

Whether in the confines of the International Space Station or a tiny hut village in sub-Saharan Africa, drinkable water is vital for human survival. Unfortunately, many people around the world lack access to clean water. Using technology developed for the space station, at-risk areas can gain access to advanced water filtration and purification systems, making a life-saving difference in these communities. The Water Security Corporation, in collaboration with other organizations, has deployed systems using NASA water-processing technology around the world.

3. Growing High-Quality Protein Crystals

There are more than 100,000 proteins in the human body and as many as 10 billion in nature. Every structure is different, and each protein holds important information related to our health and to the global environment. The perfect environment in which to study these structures is space. Microgravity allows for optimal growth of the unique and complicated crystal structures of proteins leading to the development of medical treatments. An example of a protein that was successfully crystallized in space is hematopoietic prostaglandin D synthase (H-PGDS), which may hold the key to developing useful drugs for treating muscular dystrophy. This particular experiment is an example of how understanding a protein’s structure can lead to better drug designs. Further research is ongoing.

4. Bringing Space Station Ultrasound to the Ends of the Earth

Fast, efficient and readily available medical attention is key to survival in a health emergency. For those without medical facilities within easy reach, it can mean the difference between life and death. For astronauts in orbit about 250 miles above Earth aboard the International Space Station, that problem was addressed through the Advanced Diagnostic Ultrasound in Microgravity (ADUM) investigation. Medical care has become more accessible in remote regions by use of small ultrasound units, tele-medicine, and remote guidance techniques, just like those used for people living aboard the space station.

5. Improving Eye Surgery with Space Hardware

Laser surgery to correct eyesight is a common practice, and technology developed for use in space is now commonly used on Earth to track a patient’s eye and precisely direct the laser scalpel. The Eye Tracking Device experiment gave researchers insight into how humans’ frames of reference, balance and the overall control of eye movement are affected by weightlessness. In parallel with its use on the space station, the engineers realized the device had potential for applications on Earth. Tracking the eye’s position without interfering with the surgeon’s work is essential in laser surgery. The space technology proved ideal, and the Eye Tracking Device equipment is now being used in a large proportion of corrective laser surgeries throughout the world.

6. Making Inoperable Tumors Operable with a Robotic Arm

The delicate touch that successfully removed an egg-shaped tumor from Paige Nickason’s brain got a helping hand from a world-renowned arm—a robotic arm, that is. The technology that went into developing neuroArm, the world’s first robot capable of performing surgery inside magnetic resonance machines, was born of the Canadarm (developed in collaboration with engineers at MacDonald, Dettwiler, and Associates, Ltd. [MDA] for the U.S. Space Shuttle Program) as well as Canadarm2 and Dextre, the Canadian Space Agency’s family of space robots performing the heavy lifting and maintenance aboard the International Space Station. Since Nickason’s surgery in 2008, neuroArm has been used in initial clinical experience with 35 patients who were otherwise inoperable.

7. Preventing Bone Loss Through Diet and Exercise

In the early days of the space station, astronauts were losing about one-and-a-half percent of their total bone mass density per month. Researchers discovered an opportunity to identify the mechanisms that control bones at a cellular level. These scientists discovered that high-intensity resistive exercise, dietary supplementation for vitamin D and specific caloric intake can remedy loss of bone mass in space. The research also is applicable to vulnerable populations on Earth, like older adults, and is important for continuous crew member residency aboard the space station and for deep space exploration to an asteroid placed in lunar orbit and on the journey to Mars.

8. Understanding the Mechanisms of Osteoporosis

While most people will never experience life in space, the benefits of studying bone and muscle loss aboard the station has the potential to touch lives here on the ground. Model organisms are non-human species with characteristics that allow them easily to be reproduced and studied in a laboratory. Scientists conducted a study of mice in orbit to understand mechanisms of osteoporosis. This research led to availability of a pharmaceutical on Earth called Prolia® to treat people with osteoporosis, a direct benefit of pharmaceutical companies using the spaceflight opportunity available via the national lab to improve health on Earth.

9. Developing Improved Vaccines

Ground research indicated that certain bacteria, in particular Salmonella, might become more pathogenic (more able to cause disease) during spaceflight. Salmonella infections result in thousands of hospitalizations and hundreds of deaths annually in the United States. While studying them in space, scientists found a pathway for bacterial pathogens to become virulent. Researchers identified the genetic pathway activating in Salmonella bacteria, allowing the increased likelihood to spread in microgravity. This research on the space station led to new studies of microbial vaccine development.

10. Providing Students Opportunities to Conduct Their Own Science in Space

From the YouTube Space Lab competition, the Student Spaceflight Experiments Program, and SPHERES Zero Robotics, space station educational activities inspire more than 43 million students across the globe. These tyFrom the YouTube Space Lab competition, the Student Spaceflight Experiments Program, and SPHERES Zero Robotics, space station educational activities inspire more than 43 million students across the globe. These types of inquiry-based projects allow students to be involved in human space exploration with the goal of stimulating their studies of science, technology, engineering and mathematics. It is understood that when students test a hypothesis on their own or compare work in a lab to what’s going on aboard the space station, they are more motivated towards math and science.

11. Breast Cancer Detection and Treatment Technology

A surgical instrument inspired by the Canadian Space Agency’s heavy-lifting and maneuvering robotic arms on the space station is in clinical trials for use in patients with breast cancer. The Image-Guided Autonomous Robot (IGAR) works inside an MRI machine to help accurately identify the size and location of a tumor. Using IGAR, surgeons also will be able to perform highly dexterous, precise movements during biopsies.

12. Monitoring Water Quality from Space

Though it completed its mission in 2015, the Hyperspectral Imager for the Coastal Ocean (HICO) was an imaging sensor that helped detect water quality parameters such as water clarity, phytoplankton concentrations, light absorption and the distribution of cyanobacteria. HICO was first designed and built by the U.S. Naval Research Laboratory for the Office of Naval Research to assess water quality in the coastal ocean. Researchers at the U.S. Environmental Protection Agency (EPA) took the data from HICO and developed a smartphone application to help determine hazardous concentrations of contaminants in water. With the space station’s regular addition of new instruments to provide a continuous platform for Earth observation, researchers will continue to build proactive environmental protection applications that benefit all life on Earth.

13. Monitoring Natural Disasters from Space

An imaging system aboard the station, ISS SERVIR Environmental Research and Visualization System (ISERV), captured photographs of Earth from space for use in developing countries affected by natural disasters. A broader joint endeavor by NASA and the U.S. Agency for International Development, known as SERVIR, works with developing nations around the world to use satellites for environmental decision-making. Images from orbit can help with rapid response efforts to floods, fires, volcanic eruptions, deforestation, harmful algal blooms and other types of natural events. Since the station passes over more than 90 percent of the Earth’s populated areas every 24 hours, the ISERV system was available to provide imagery to developing nations quickly, collecting up to 1,000 images per day. Though ISERV successfully completed its mission, the space station continues to prove to be a valuable platform for Earth observation during times of disaster.

14. Describing the Behavior of Fluids to Improve Medical Devices

Capillary Flow Experiments (CFE) aboard the space station study the movement of a liquid along surfaces, similar to the way fluid wicks along a paper towel. These investigations produce space-based models that describe fluid behavior in microgravity, which has led to a new medical testing device on Earth. This new device could improve diagnosis of HIV/AIDS in remote areas, thanks in part to knowledge gained from the experiments.

15. Improving Indoor Air Quality

Solutions for growing crops in space now translates to solutions for mold prevention in wine cellars, homes and medical facilities, as well as other industries around the world. NASA is studying crop growth aboard the space station to develop the capability for astronauts to grow their own food as part of the agency’s journey to Mars. Scientists working on this investigation noticed that a buildup of a naturally-occurring plant hormone called ethylene was destroying plants within the confined plant growth chambers. Researchers developed and successfully tested an ethylene removal system in space, called Advanced Astroculture (ADVASC). It helped to keep the plants alive by removing viruses, bacteria and mold from the plant growth chamber. Scientists adapted the ADVASC system for use in air purification. Now this technology is used to prolong the shelf-life of fruits and vegetables in the grocery store, and winemakers are using it in their storage cellars.

For more information on the International Space Station, and regular updates, follow @Space_Station on Twitter. 

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The Red Tide

The appearance of a red is never a good thing. People dread these tides because not only does it look like some horrific biblical omen, it smells terrible and causes schools of fish to choke and die. But what is a red tide and what causes them?

A red tide is an algal bloom. It consists of a type of algae called dinoflagellates.

The bloom occurs when conditions are optimal for the algae. This means the temperatures are perfect, salinity is at good levels, and there is an excess of nutrients. These extra nutrients are usually from agricultural runoff (fertilizers washing into the ocean). The algae is in such excess that it chokes fishes gills causing mass deaths. Shellfish like clams and mussels are filter feeders and will become contaminated by the algae making them toxic to eat. There is no way to control an algal bloom, we just have to wait for the conditions that caused it to return to normal levels (usually this means all of the excess nutrients getting used up)and the algae to die.

Because of the mortality and contamination the bloom causes it has very bad effects on local economies. Some blooms can also give off gases that can cause nausea in the people near it, also making it unsafe to swim in which in turn effects the tourism in these areas. Work is being done to reaserch these blooms to forecast when and where they will occur (like the weather) so that people can prepare for the effects it has.

Now I want to be very clear on one thing: NOT ALL ALGAL BLOOMS ARE HARMFUL. Often they are helpful: they provide extra food for larger organisms that we fish for and eat. The difference between a harmful algal bloom and a non-harmful one is dependent on the type of algae that is blooming.