h 14

Molecule of the Day - DDT

Dichlorodiphenyltrichloroethane (C14H9Cl5), more commonly known as DDT, is a colourless, tasteless solid under room conditions. It was used as an insecticide during the 1940s-1970s, and gained notoriety after Rachel Carson’s 1962 book, Silent Spring, which highlighted the health and environmental effects of DDT.

DDT acts by binding to voltage-gated sodium ion channels of neurons (as seen on the left of the diagram below), causing these channels to be permanently open instead of opening only upon the arrival of an action potential. Consequently, there is a continuous influx of Na+ ions into the neuron, which triggers a series of rapid action potentials and hence neuronal impulses. This leads to rapid muscle contractions, spasms, and death.

While this effect does not occur in humans and other non-insects, it is still moderately toxic, and as been shown to be an endocrine disruptor. Therefore, chronic exposure to it can lead to tumour formation, developmental problems, and birth defects. DDT is also considered to be a possible carcinogen.

Due to the hydrophobicity of DDT, it tends to accumulate in the lipids of living organisms rather than in the environment. This results in biomagnification, in which its concentration increases upon going up the food chain, as each organism of a rung of the chain consumes multiple prey. Consequently, the usage of DDT affected the populations of many birds of prey, such as the bald eagle.

In 1962, Rachel Carson published the book Silent Spring, which highlighted the negative effects of the usage of DDT and other pesticides on the environment and biodiversity. This book was revolutionary; it sparked a heated debate on pesticides and contributed to the 1972 US ban on DDT. The world followed suit; most countries around the world now prohibit the use of DDT, except for limited disease vector control purposes, such as for malaria.

DDT is synthesised by the condensation of a molecule of chloral and 2 molecules of chlorobenzene via an electrophilic substitution reaction, producing water as a by-product.

Requested by anonymous

5

I found peace in solitude. *mostly plus sizes*

(store links below)

a $27 / b $11 / c $26 / d $17 / e $25 / f $62 / g $14 / h $8 / i $19 / j $23 / k $15 / l $50 / m $22 / n $47 / o $38 / p $36 / q $65 / r $21 / s $28 / t $25 / u $16 /  v $20 / w $60 / x $25 / y $16 / z $25 / aa $13 / ab $56 / ac $18 / ad $19 / ae $17 / af $14 / ag $33 / ah $14 / ai $20 / aj $25 / ak $25 / al $13 / am $35 / an $30 / ao $20

youtube

Since I guess people value my opinions (sometimes maybe) here’s songs from my favorite releases of 2016. I probably left stuff out because I’m an idiot, but yeah here’s some good shit

0:00 S U R V I V E - A.H.B.
4:14 B BOYS - SOUND FREQUENCY
7:16 URANIUM CLUB - GOD’S CHEST
9:56 BB EYE - BUZZSAW BREAKFAST
11:37 DISCO 3000 - I CAN’T GIVE
12:52 DJBO - PERFECT IMITATION
14:15 THE BRAIN - TOO MUCH TO DREAM
20:21 WARM BODIES - THE PSYCHIC CONNECTION
23:03 GLITTER - GARDEN
24:44 RIK & THE PIGS - OFF/ON
28:03 PORNO GLOWS - DU U ?
29:31 FUR COAT - THIS PLANET IS DOOMED
31:58 LPC - WALLET SIZED WILDFIRE
32:15 BIB - PSYCHEDELIC PARALYSIS
33:57 MIRROR - SATURN
35:38 LATISHIA’S SKULL DRAWING - HEIRLOOM
36:48 LUMPY & THE DUMPERS - I’M GONNA MOVE TO NEW YORK
38:45 SKELETON - LOCKED UP
39:57 OAF - REVENGE
42:46 GAZM -  FUCK YOU
43:53 V-SECT - SAY GOODNIGHT
45:37 MALPHAS - LA TERRE DISPARUE
48:32 STILLBORN FAWN - ARTERIAL DRAINAGE
50:24 FLESH PRISON - EMPTY VESSEL
52:57 NIHILISTIC FIT - FALLING APART
56:26 HUMILIATION - LOW HANGING FRUIT
57:37 SIYAHKAL - TOFANGAM KOO
58:50 LPC - GAME STOP
59:11 MALA LECHE - TRAGATE LA LECHE
1:00:00 BIG BLEACH - BAD BOY LEATHER II
1:01:06 RAZORBUMPS - S.T.I.C.K.
1:03:48 C.C.T.V. - BIG PLAN
1:06:46 LIVIN’ THING - AN ISLAND
1:08:49 BULSCH - BOBBY POPPA
1:09:55 UROCHROMES - COUNTRY JOE
1:11:05 LAUGHTER - LIFE’S NO FUN
1:12:21 WARM BODIES - I’LL GETCHA
1:14:41 DUMSPELL - DTMFU
1:16:01 COWBOYS - I SPY
1:17:25 DAME - ON THE LINE
1:20:16 URANIUM CLUB - WHO MADE THE MAN?
1:25:15 HAIRLONG & FREEKY - 2
1:26:21 CHASM - SOUL SPIRAL
1:27:52 TRIAGE - SECRET WAR
1:28:49 BIGHAND//BIGKNIFE - DEPOGNOG
1:32:25 LPC - ZATARANS
1:33:33 BODY OF LIGHT - HOLDING YOU
1:36:23 LPC - I'MMA WHOOP YUH
1:36:42 CRUMB - COOL
1:37:59 LASSIE - WHO LET THE DOGS OUT
1:41:56 MOTH SLASHER - ZERO RETURN
1:43:37 ACRYLICS - MOMMA’S BOY
1:46:03 RUBBER MATE - BLOODY & DRUNK
1:47:37 PRIME TARGET - YOUTH CORPS
1:48:29 HARAM - المجانينا
1:50:03 NURSE - I CAN SEE YOU
1:51:18 NOSFERATU - WAR ON YOU
1:52:05 IMPALERS - NAZI BURNING MAN
1:53:14 SEPSIS - NO LIFE
1:54:25 LCP -  YO’ MAMA’S RIBSUH
1:54:34 BETA BOYS - NASTY NEIGHBOR
1:55:43 JJ DOLL - SHE’S ONTO YOU
1:57:48 WARTHOG - FUNCTIONING WORLD
1:59:08 RITUAL ORDER - ISA
2:00:57 URANIUM CLUB - OPERATION PT 2

Spe Pointless Trivia

I was browsing through twitter and someone in Japanese brought up that the first time Green(m) calls Blue(f) by her name is once in volume 14.

It took him over 11-12 volumes to say her name and he doesn’t even say it to her directly until Volume 24. W-H-A-T

That’s some deep character development there.

Volume 14:

Japanese reference:

Volume 24:

Japanese reference:

Italian Meals

Breakfast (7-11 h) is always a light meal, usually consisting of a cappuccino or coffee and brioche (like croissant) at home or at a bar (often standing up), or coffee and biscuits and possibly a piece of fruit or yogurt at home.The brioche can be plain (liscia), filled with jam (con marmellata), custard (con crema), or chocolate (con cioccolata). Note: For Italians, cappuccino is a breakfast drink. Most will not drink it later in the day. 

Lunch (12:30-14:00 h in the north, 12:30-14:30 in the south: 

Antipasti (starters) - light starters typically salumi (cold hams, salami)

Primo piatto (1st course) - usually risotto, pasta, or (rarely) soup

Secondo piatto (2nd course) - meat or fish

Contorni (side dish) - vegetables (vedure) or salad (insalata)

Dolce (dessert) - cakes, icecream or seasonal fruit (ordered separately)

Caffé espresso to finish the meal.

During the week most Italians will eat at least a primo + secondo and probably fruit. For a special lunch all of the above will be eaten. For a quick snack on the go, one might have a panino (filled roll) at a bar. Typical fillings are mozzarella & tomatoes, prosciutto cotto (cooked ham) or crudo (raw ham). 

Merenda (16:00 h): snack for children (usually bread, fruit, yogurt, or icecream)

Dinner (20:00-22:00 h): Depending on the person, it may be a lighter meal like salad or either primo or secondo as above. Many people (especially if eating out) will have the full works again. Going out for a pizza is also very popular. 

Bars: Bars are usually open from 7:30 h. They serve breakfast in the morning, panini at lunch, icecream mid afternoon, aperativi early evening, and coffee throughout the day. Many also sell cakes and pastries (pasticceria). If it’s also a tabaccheria, they will sell stamps, phone cards, bus tickets, parking, car tax, and lottery tickets. When ordering to eat at a busy bar, you usually have to pay for what you want at the till (cassa) first, then take the receipt and repeat your order to the barman. If it’s quiet and you are known, they may take your order and you’ll pay at the end.

Sailors Relax On The Deck Of The Gunboat Hunchback

USS Hunchback was a side-wheel, steam-powered gunboat used by the United States Navy during the Civil War

Type: Gunboat
Displacement: 512 long tons (520 t)
Length: 179 ft (55 m)
Beam: 29 ft (8.8 m)
Depth of hold: 10 ft (3.0 m)
Propulsion: 1 × 40 inch bore, 8-foot stroke vertical beam steam engine; sidewheels
Speed: 12 knots (22 km/h; 14 mph)
Complement: 125 officers and enlisted
Armament:• 3 × 9 in (230 mm) guns
• 1 × 100-pounder Parrott rifle