Buphthalmos (literally “ox-eye”), or “The Eye of Juno”, is a clinical sign that can signify infantile glaucoma, and most often occurs in children between birth and 3 years of age. It is an apparent enlargement of the eyes, but is really just the increased ocular pressure pushing the sclera outwards.
This occurs due to abnormalities in the anterior chamber angle of the eye, preventing drainage of aqueous humor. This raises intraocular pressure and presents with corneal oedema as seen in this photograph. Surgical intervention is required, using shunt and drainage procedures.