Oh, I love soup. If the only thing I could do was lay in bed all day and eat soup, I’d be happy. I wouldn’t even have to taste it. I could just take it through a tube. That would actually be better ‘cause I wouldn’t even burn my mouth.
the idea that a hijabi woman can’t be a superhero is absurd because you got ones like batman, daredevil, cat woman, iron man, spiderman, deadpool covering their head and sometimes even their face when they’re out fighting crime… but a woman who’s covering her hair b/c she’s a hijabi is… impossible…
MS breakthrough: Replacing diseased immune system halts progression and allows repair
A clinical trial published in The Lancet, a top medical journal,
shows that an intensive procedure that completely wipes out the immune
system and then regenerates a new one using blood stem cells can
eliminate all signs of damaging brain inflammation in people with early,
aggressive multiple sclerosis (MS), and facilitate lasting recovery.
by Dr. Harold Atkins and Dr. Mark S. Freedman of The Ottawa Hospital
and the University of Ottawa, the trial included 24 participants who
were followed for up to 13 years. The $6.47 million trial was funded by
the MS Society of Canada and its affiliated Multiple Sclerosis
Scientific Research Foundation. The research was also supported by The
Ottawa Hospital Foundation, The Ottawa Hospital Department of Medicine
and Canadian Blood Services.
“Our trial is the first to show the complete, long-term suppression of
all inflammatory activity in people with MS,” said Dr. Atkins, a stem
cell transplant physician and scientist at The Ottawa Hospital, and
associate professor at the University of Ottawa. “This is very exciting.
However, it is important to note that this therapy can have serious
side effects and risks, and would only be appropriate for a small
proportion of people with very active MS. People with MS who have had
significant disability for a long time would likely not benefit.”
procedure should be considered as a treatment option for people with
early, aggressive MS,” said Dr. Freedman, a neurologist and senior
scientist at The Ottawa Hospital and professor at the University of
Ottawa. “Although this trial was relatively small, it was intensive,
with the longest prospective follow-up of any such treatment group to
date, and that is what makes the results so convincing. However, this is
a very complex procedure that should only be performed at very
specialized centres with expertise in both the management of MS patients
and blood stem cell transplantation.”
MS affects approximately
2.3 million people around the world, causing symptoms that range from
blurred vision to extreme fatigue to partial or complete paralysis. It
occurs when the immune system – which normally protects against foreign
disease-causing organisms – mistakenly attacks the body’s own central
nervous system, which includes the brain, spinal cord and optic nerve.
Early in the disease, people often experience temporary episodes of
worsening symptoms accompanied by active inflammation in the brain
(called relapses), whereas later on, disease progression is inevitable.
trial evaluated a treatment called immunoablation and autologous
hematopoietic stem cell transplantation (IAHSCT). The procedure begins
by giving a person medication to coax their hematopoietic stem cells to
migrate from their bone marrow into their blood. These stem cells are
then collected from the blood, purified and frozen. Then, high doses of
chemotherapy drugs are used to eliminate the person’s diseased immune
system. The stem cells are then transplanted back into the same person,
so that they can give rise to a new immune system that has no “memory”
of the previous pattern of attacking the central nervous system.
trial included 24 participants with aggressive, relapsing MS. They were
followed for anywhere between four and 13 years after treatment (with a
median post-treatment follow up of 6.7 years).
After the treatment:
Not a single participant experienced a clinical relapse (zero relapses
in 179 patient-years), whereas before treatment, the participants
experienced an average of 1.2 relapses per year (167 relapses in 146
Not a single new active inflammatory lesion
could be detected in the brains of any of the participants (zero lesions
on 327 MRI scans) whereas before the treatment, participants had 188
lesions on 48 scans.
Not a single participant required MS-specific drugs to control their disease.
70 percent of participants experienced a complete stop in disease progression.
The average rate of brain shrinkage, typically a measure that
correlates with MS progression, returned to levels associated with
40 percent of participants experienced some
lasting reversal of symptoms such as vision loss, muscle weakness and
Some participants were able to return to work or school, regain the ability to drive, get married and have children.
Trial participant Jennifer Molson was diagnosed with MS in 1996, when she was just 21. She received her transplant in 2002.
my transplant I was unable to walk or work and was living in assisted
care at The Ottawa Hospital Rehabilitation Centre,” she said. “Now I am
able to walk independently, live in my own home and work full time. I
was also able to get married, walk down the aisle with my Dad and dance
with my husband. I’ve even gone downhill skiing. Thanks to this research
I have been given a second chance at life.”
“Even if you don’t understand the language, I’m sure you can understand the time I spent on trying to find the good sentence and the good scenario. I’m sure you can feel this, even if you don’t understand every single word.”