genetically engineering

I know we’re always talking about how Pacific Rim embraces the ridiculousness of the human race because “just build a giant robot to punch them in the face” is probably the most full-on human bullshit response we could have thought of to an invasion of giant aliens, but can we pause and also consider that the aliens are basically doing the same thing

like they wanted to invade us and their first thought about how to do so was “let’s genetically engineer giant fucking monsters that will crawl out of the depths of the ocean and trample cities”

Pacific Rim is just the story of two species that on a scale from 1 to 10 respond to every problem with a 17

Been seeing a lot of these Humans Are Space Orcs posts around- which is good, because I love them- and I started thinking: in sci-fi stories, humans in the future often have a bit of genetic engineering- like disease immunity or faster healing or even just a lack of body hair.

And I had a thought- what if that’s just us? What if we’re the only species to engineer ourselves like that? Imagine how freaked out they’d be;

“You’re telling me that you alter your own genetic code?”

Or take it a little further- we’re the only species to use vaccines. Every other race just toughed it out and evolved past it, but humans injected ourselves with weakened diseases to make ourselves stronger. 

Or even further back, when people used to drink poison to gain an immunity- imagine that reaction:

“OH MY GROP THEY DRINK POISON TO GET STRONGER THAT’S IT FUCK THIS PLANET I’M OUTTA HERE”

  • what i expected going into see Logan: a bloody gory action packed Wolverine film with zero chill and maximum violence
  • what i got: a father/ son father/daughter roadtrip flick through children of men stylescape of dystopian heartbreak that deals with issues of human trafficking and the exploitation of women of color's bodies and genetic engineering ethics that made me cry multiple times

It is the age of technology and science. Through some stroke of genius, some humans are able to be genetically engineered. Every person in the USA must donate a blood sample to see if they are a match. Out of all the people, only you and 6 others are considered “Low risk of failure-high probability of success”. Write a story about who you and the others become and what changes, not only physically, but emotionally and mentally.

A groundbreaking gene therapy treatment which boosts a patient’s own immune cells has been shown to clear disease from one third of terminal patients.

US pharmaceutical company Kite Pharma released results from the first six months of its trial of the new treatment, called CAR-T cell therapy.


Some 36 per cent of the 101 patients on the trial were still in complete remission at six months, and eight in 10 saw their cancer shrink by at least half during the study.

“The numbers are fantastic,” said Dr Fred Locke, a blood cancer expert at Moffitt Cancer Center in Tampa who co-led the study.

“These are heavily treated patients who have no other options.”

The treatment, which has been dubbed ‘a living drug’ by doctors, works by filtering a patient’s blood to remove key immune system cells called T-cells, which are then genetically engineered in the lab to recognise cancer cells.

Cancer cells are very good a evading the immune system, but the new therapy essentially cuts the brakes, allowing immune cells to do their job properly.

Martin Ledwick, Cancer Research UK’s head cancer information nurse, said: “These results are promising and suggest that one day CAR-T cells could become a treatment option for some patients with certain types of lymphoma.

“But, we need to know more about the side effects of the treatment and long term benefits.”

Patients in the study had one of three types of non-Hodgkin lymphoma, a blood cancer which affects 13,600 patients in Britain, and had failed all other treatments. Most patients with such an advanced condition only live for six months but half of the trial group are still alive nine months since the trial began, and a third may be cured.

Dimas Padilla, 43, of Orlando, who was warned his case was worsening after chemotherapy stopped working, is now in complete remission after undergoing the therapy last August.

After learning his cancer was probably terminal he said: "I was thinking how am I going to tell this to my mother, my wife, my children,” he said.

After CAR-T therapy he saw his tumours “shrink like ice cubes” and is now in complete remission.

“They were able to save my life,” Mr Padilla added.

However there are still concerns that the treatment has significant side effects, and can even kill some patients, as it puts the immune system into a state of over-drive. During the trial two people died from the therapy, rather than their cancer.

Of the study participants, 13 per cent developed a dangerous condition where the immune system overreacts in fighting the cancer, and roughly a third of patients developed anaemia or other blood-count-related problems.

Nearly one third also reported neurological problems such as sleepiness, confusion, tremor or difficulty speaking, but these typically lasted just a few days.

The scans show how cancer has disappeared after just three months, and the remission has continued
The scans show how cancer has disappeared after just three months, and the remission has continued
Full results will be presented at the American Association for Cancer Research conference in April and the company plans to seek approval from European regulators later this year.

“It’s a safe treatment, certainly a lot safer than having progressive lymphoma,"said the cancer institute’s Dr Steven Rosenberg,

Other companies, such as Juno Therapeutics, have had to halt trials into CAR-T treatments following patient deaths.

anonymous asked:

Do u know any fics where Sherlock is jealous?

NONNNNYYYYYY YES. 

I love Jealous Sherlock so much. I know I’m missing a tonne of them here, but these are the ones I could quickly find or remember being Jealous!Sherlock! I’m also adding Possessive Sherlock here as well, because I LOVE LOVE LOVE “his / My John” SO SO MUCH and literally I fave every fic that has it in there. GUH. 

JEALOUS SHERLOCK

  • Unimpressed by 221b_hound (M, 3106 w.) – Sherlock has no intention of attending the Met’s New Year’s Eve party. The start of a new year is all but meaningless to him. But he ends up there anyway, having odd conversations, and John does not find Sherlock’s jealousy the slightest bit cute. And then there is dancing. Part 10 of Unkissed
  • Unforgiven by 221b_hound (M, 4721 w.) – Sherlock’s latest case is for his ex boyfriend, the brilliant and handsome Professor Victor Trevor. John is not too happy about that. But things aren’t what they seem, an old friend of John’s is involved in the case, and John has a few surprises up his sleeve. Also - a proposal! Part 16 of Unkissed
  • Mine (He Says While Still Being Smol) by beejohnlocked (E, 1,319 w.) – A suspect flirts with John. Sherlock gets a bit jealous. Okay, a LOT jealous.
  • Maintaining A Personal Life by Gingerhermit (E, 24,284 w.) – Sherlock and John discover some interesting revelations about each other’s sexuality, which lead them both to question the assumptions they’ve made about one another for years. In the midst of their mutual discoveries, a dangerous psychopath looms on the side-lines who threatens to destroy their new beginning.
  • For you, there’s only me by shock_blanket (E, 19,557 w.) – Sherlock realizes he has fallen in love with John, but believes he is unlovable. Cue lots of pining and jealousy on Sherlock’s part, followed by our favorite cuddly marksman making it all better. Because for Sherlock, there’s only John.
  • Matters of National Security by mistyzeo (E, 8,465 w.) – John starts dating a male client of Sherlock’s, and Sherlock can’t figure out why he’s so incensed about it.
  • Velvet by headlessjess (G, 1,155 w.) – It’s the day, the wedding day - John and Mary, getting married. And then there’s Sherlock, in pain and in love, without knowing how to deal with it.
  • 5 Times John Got the Girl (and lost her) and 1 Time John Got the Guy (and kept him) by LiviKate (M, 21,695 w.) – John has always had good luck with the ladies. He’s charming, friendly and funny, not to mention great in bed. However, his usual skill with the opposite sex is constantly being thwarted by Sherlock and his outbursts. How will John ever get a leg over when Sherlock is always cockblocking him?
  • Five Times John Noticed But Didn’t Really by ScandalousMinds (T, 6,383 w.) – 5 times John (thought) he noticed something peculiar about his and Sherlock’s relationship but really missed the obvious.
  • The Kissing Disease by cottonballz_of_death (E, 30,856 w.) – John brings home a boyfriend, shocking Sherlock, who long ago gave up hope that his straight flatmate would ever take a romantic interest in him. In a bid to reconnect with John, he tries to infect himself with a “harmless” virus. Neither of them is prepared for the emotional fallout that results.
  • Surety by hudders (G, 2,477w.) – “Sherlock is pissed because it seems that four pints of larger, two shots of tequila and a glass of wine has resulted in Lestrade becoming a little bit too friendly with everyone. And by everyone, Sherlock really means John.”
  • Butterfly, Pinned Under Glass by billiethepoet (E, 4,648 w.) – It started as a desire to keep John safe and whole, and ended up as just desire.
  • Correspondence by Cleo2010 (T, 8031 w.) – Sherlock’s been spirited away on a case for Mycroft. Part of the deal was that he and John could communicate via letter until the case was completed. Maybe the cliche is true, absence does make the heart grow fonder. Or perhaps something is growing on the feet in the fridge. Read their letters month by month. Written after series one.
  • Presence by LostGirl (M, 8625 w.) – Sherlock has recently noticed a shift in his own perceptions, but he can’t quite figure out when it started.
  • Obsession, Appassionato by shinychimera, Yeomanrand (E, 4,249 w.) – John is late, and he hasn’t called, and Sherlock works himself into a state. Part 1 of Love and Ysaye (FAVE!!)
  • Interlude by sussexbound (SamanthaLenore) (G, 2,837w.) – “Are you actually doing anything?” Sherlock scowls. “What?” “Are you busy? Because if not, I could use your help peeling potatoes.” “I’m not eating what you’re making. Why should I peel the potatoes?” John just shakes his head. “Because it might be a polite and thoughtful thing to do for the person who loves you. Just a tip.”Oh…Part 8 of The Homecoming
  • Understanding by sussexbound (SamanthaLenore) (T, 4,556 w.) – John’s face stretches into a smile that fades again, just as quickly. “It just comes like that, sometimes—all of a sudden. You don’t expect it.” He murmurs against Sherlock’s skin. “What does?” “Grief.” Part 9 of The Homecoming
  • Sibling Rivalry Or Fighting Over John Watson by Jessa7 (T, 8K+ w., Romance and Humour, FFNet) – Mycroft is just as much of a genius as Sherlock is. He keeps randomly kidnapping John for chats, and the locations get better. Cue Sherlock’s younger sibling complex rearing up and jealousy ensues.
  • Come Home by hudders-and-hiddles (E, 3,763 w. | more pining than jealous but close enough) – When John leaves for a medical conference, Sherlock tries to entice him back home.
  • The Semantics of Crop Circle Formation: a case study by Sherlock Holmes [unpublished] by canolacrush (M, 41,710 | Cockblocking Sherlock) – “Look at these photographs,” I said, gesturing to the wall of crop circles. “What do you observe?”“Crop circles,” John replied.“Obvious. What else?”“Are…are those intestines surrounding them?”“Yes. The majority are bovine and ovine in origin. The farmers who have acquired these crop circles in their fields have also had a tenth of their livestock murdered and arranged thus.”“Why?” John said, presumably in a rhetorical fashion.I detest rhetorical questions. “That is what I must find out, John.”
  • Down with this Ship by FrostedFlame (PinkOrchid) (M, 10,862 w.) – Sherlock drags John undercover to a gay bar - for a case, of course - looking forward to seeing John flustered by their surroundings (since you know, he’s NOT GAY). John decides that he has hidden both his orientation and his feelings for his daft flatmate for far too long. He is done hiding, time to be honest with his bloody best friend in the world. He just hopes it won’t change anything between them. And then it does.
  • That Partitioning of the Things of Youth by wearitcounts (Sher_locked_up) (E | 35,353 w.) - Victor Trevor is in town, and nobody’s happy. [[I really like this one. Jealous John AND Sherlock and lots of Angst]].
  • Paparazzi by SilentAuror (E, 10,543 w.) – John moves back into 221B Baker Street after his marriage falls apart and the paparazzi won’t leave him and Sherlock alone about the status of their supposed relationship. Sherlock, of course, never denies it, until one day he does…
  • Pattern Behaviour by SilentAuror (E, 14,835w) – Sherlock doesn’t even know why he resents John’s dates so much. Until the day he does know. Slight angst, unrequited feelings (but don’t let that scare you off!) (FAVE!) 

OBSESSIVE / POSSESSIVE SHERLOCK

  • Perdition’s Flames by i_ship_an_armada (E, Treklock, 63,435 w., | mild Possessive Sherlock) – Sherlock would do anything to save him. Risk anything. Give anything. His money, his life. His soul. What he does, though, is change both of their destinies forever. Genetic re-engineering is the only option left. It turns out researchers underestimated the life expectancy and potential abilities of genetically re-engineered subjects. The British government and what would eventually become the United Federation of Planets, however, had not. Part 1 of PF Universe
  • The Things You Hide *Adult Edition* by verityburns (E, 10,821 w.) – Sherlock and John have been working and living together for nearly a year, each finding the other’s friendship to be the one thing they would not risk or want to live without. Until something happens to disturb the status quo…
  • Let Go by thisisforyou (G, 2,743 w.) – In the end, separating John’s things from Sherlock’s in the chaos of their sitting room is like pulling a limpet from a wet rock. Especially when the rock is clinging on for dear life, because Sherlock doesn’t want to let go. 
  • In the cherry blossom’s shade by Eliane (M, 3,934 w.) – “This isn’t new. Sherlock has already done this – has gone through cities, and dingy hotels, and sleepless nights but it was different before. John wasn’t there before. They’re in this together.”
  • The Marriage Proposal Negotiation by Goddess_of_the_Night (G, 2161 w.) –  Sherlock hasn’t ever really done anything the traditional way, so of course it wouldn’t bother him to propose to John even though they’re not even dating. And the fact that John is already on a date with someone else when he decides to do it? Tedious. Marrying John was the only thing he could do to ensure John was his.
  • The Light of Day by allonsys_girl (M, 7297 w.) – Rewrite of the end of Sign of Three. John actually notices Sherlock leaving the reception early, and chases after him. Angsty Johnlock. Happy ending, for sure. Part 1 of The Light of Day
  • Let the Sun Fade Out by nothingislittle (E, 2711 w.) – “He could warm the sun itself, Sherlock thinks, could heat their flat with just his presence, could brighten the room with one dazzling smile or just the sparkling in his eyes. Everything hurts when John looks this beautiful, but it’s a dulcet, aching pain, one that consumes Sherlock from the inside, that sends soft pangs through his abdomen and lodges a lump solidly in his throat. John glows, he glitters, he’s light itself, Sherlock thinks, and doesn’t even bother to scold himself for exaggerating, because he’s not, he’s not, John is everything, he’s beautiful and he shines, he’s everything.”
  • On a Sunday Morning by SD_Ryan for jimmytiberius (G, 3136 w.) – Sherlock has a little problem. He can’t stop obsessing about John Watson.
  • His by I’m Nova (T, 1K+ w., Humour & H/C) – Sherlock doesn’t share what he’s fond of. (FAVE!!)
  • Foresight by niffler09 (K, 2K+w) – It’s raining and neither John nor Sherlock have an umbrella so they huddle under Sherlock’s coat. And then Mycroft walks past and makes smartass remarks. (FAVE!!)
  • Possessive by Fang323 (T, 850w. H/c & Friendship) – His John did not belong. Not here. Not in this blasted hospital. It simply was not logical.

As I’ve said in the past, all my rec lists are of fics I’ve read, so I’m sure I’m missing a tonne more that are probably on my MFL list, but please feel free to add your own recs! 

the year is 2097. phase 32 is in motion, jamie and damon are both heads in jars like all those people in futurama. scientists have genetically engineered stem cells to create the perfect, real gorillaz. they revolt against the establishment. somewhere, the evangelist and cyborg noodle play cards together

this blog was created in a laboratory by scientists that were created in an experiment in a different laboratory with the goal of genetically engineering the most basic, milquetoast human beings imaginable while still fitting within the confines of the laws of physics and reality

reddit.com
Reddit Science AMA on genetically engineering American chestnuts
Hi Reddit! We are a team of scientists at the College of Environmental Science and Forestry in Syracuse, New York, and we’ve been working for 27...

TLDR: This project is using genetic engineering to create American chestnut trees that are blight-resistant so they can restore the species to the wild!  It’s really cool and controversial, and if you have ever had questions about GMOs, how they work and whether you should really fear them or not, you should go ask these guys!

The long version:

About 100 years ago, the American chestnut began to effectively go extinct, thanks to an invasive fungus.  Before then, there were about 4 billion of them, and they made up about ¼ of forests in eastern North America, and they produced loads and loads of nuts that made up a large part of the natural diet of North American wildlife.  It was a huge deal, even though a lot of us who were born since then don’t really notice what a massive change it made to the health of the North American environment.

So this team of scientists has been using genetic engineering to create an American chestnut tree that is resistant to the chestnut blight.

It’s controversial work–it would be the first genetically engineered organism to be deliberately released into the wild–but the team has spent 30 years successfully creating this tree, and now they’re spending the next five years running tests to make sure it’s safe and can earn regulatory approval (assuming the federal situation doesn’t go completely bananas in the near future).  Their argument is that this tree is all but identical to native American chestnuts–the only difference is they’ve extracted a single gene from wheat that confers blight resistance and inserted it into the chestnut trees. 

Yes, that does make this tree technically a GMO.  But GMO is actually a pretty complicated thing, and you don’t get the full story either from Monsanto or from the anti-GMO purists.  These guys work for a public college and are not going to patent their work, and they are willing to talk freely about EXACTLY what the process is and what regulatory approval entails and how this technology can be used in both responsible and dangerously irresponsible ways.

I’m hearing speculations that the baby in the pod from the s2 finale might be Reign, aka a genetically engineered alien from Krypton who doesn’t know her origin and is a leader of an alien group called Worldkillers. who also, according to comics, offers Kara to join her but when Kara refuses it leads to them fighting. 

another important piece of information is that she has a sword

this lowkey has me excited for s3 now. I guess the pods get higher in quality with each new season

youtube

They made a spider goat for some reason

writingisproseandpotatoes-deact  asked:

Hi! I'm writing a story, and I was wondering if it were possible for birds to evolve to glow in the dark within the next hundred years? If that is impossible, could they be made to glow?

So they definitely could be made to glow! There’s lots of genes out there that code for fluorescent proteins. My favorite is a jellyfish gene called GFP (which stands for green fluorescent protein), which codes for a green protein that glows under blue-violet or UV light. (however, it doesn’t necessarily glow in the dark, I’ve looked over the other known fluorescent proteins and I’m not sure of one that specifically glows in the dark, but I believe GFP or one of its derivatives would do the job, as they’re specifically related to jellyfish bioluminescence! It’s also possible I’m getting way too into specifics here, so moving forward, feel free to read GFP as ‘generic fluorescent protein which also glows in the dark because scifi’)

This gene is easily extracted and has been sequenced already (fun fact: we do need to sequence genes before we can work with them extensively - that’s why it was such a big deal to sequence the human genome!) so it’s often used as a marker in the biotech industry (not sure if your gene is being expressed? Just add GFP! You’ll know if it glows!)

To actually make an organism glow, you’d need to combine GFP with a gene that codes for a protein involved in the actual structure of the organism. For example, when I was in school, I did a project where I made yeast cells glow by combining GFP with one of the major structural genes of yeast, creating what’s called a recombinant gene. This meant that instead of just coding for the protein it originally coded for, (which was used to build the cytoskeleton) it coded for both that protein, and for GFP. When I put this gene into new yeast cells and let them colonize, their cytoskeletons also contained GFP, making them glow!

This is what GFP looks like in action! Yeast cells are pretty simple, being single-celled organisms and all, but birds are a little more complicated. It could be done (and combining some mammal DNA and even human DNA with GFP already has been done!), but it would take more time than just a semester. I would say several years at the minimum, and they might run into some problems with animal rights laws/ethics laws depending on the government where your scientists are science-ing.

You also wouldn’t have all birds glowing, just a specific species, probably manmade. It’s possible this could happen naturally, but unlikely, and you’d probably only see isolated cases unless something in their environment was making it more useful to glow than not. (It’s likely the opposite would happen - it would make them much more visible to predators, for one, and I’m not sure what might offset that to make it useful enough to be selected for. However, birds are weird, and sometimes select for things harmful to their survival because they think it looks pretty, so it’s entirely possible that happened.) You’d be unlikely to see an entire glowing species develop within 100 years from natural evolution alone unless the glowing trait was being heavily selected for.

This is such a neat idea! Good luck with your story!

League of Villains: this is Noumu. He’s gifted with more than one incredibly powerful quirk and is genetically engineered to be one of the strongest creatures in the world, capable of defeating even All Might

Class 1-a: this is our dad Aizawa we love him he’s fast