folic-acid

I love knowing that out there are many people who ship supercorp and adore Katie Mcgrath, but also ship sanvers and respect Floriana Lima

Quest to mermaid hair.

So this is my current lenght, and my first goal will be reaching bra-strap lenght, although it might take quite a while…

I will be alterning between Mane N Tail and Biotin&Collagen shampoo.

I will also be taking 3000mcg of Biotin and 2000mcg of Folic Acid a day. Might take more if my hair doesn’t respond well in the next month or so.

And finally, I will be putting coconut oil in my hair once a week.

Will uptade in a month to see how this goes :D

EDIT: I added 2000mcg of MSM a day, and decided to stop using heat for a month.

Dear Immune System,

I know you are trying to help, I really do. But my joints are not bad guys. We actually like our fingers, wrists, elbows, shoulders, toes, ankles, knees, and hips. We love them, to be honest. So if you could stop tearing them apart, I would really appreciate it. I guarantee we will need them in our future!

Your loving, but very aggravated and stiff, body.

Molecule of the Day: Folic acid

Folic acid (C19H19N7O6), also known as Vitamin B9, is a yellow powder that is insoluble in water under standard conditions. It is essential to metabolism and cell division, and is found in many fruits and vegetables.

Folic acid (in the form of tetrahydrofolate [THF], a metabolite) plays an integral role in methylation and other metabolic reactions by carrying one-carbon groups that react with other substrates. Additionally, it also is a key intermediate in the synthesis of purines and hence DNA via N10-formyl-THF (see diagram below).

It is also essential in the process of cell division, since the methylation and demethylation of DNA, which controls gene expression, and the synthesis of nitrogenous bases, which is required for DNA replication, are absolutely key to this process. 

Folic acid is commonly found as a food additive, as it lowers the probability of neural tube defects occurring in pregnant women. These are characterised by openings in the spinal cord or brain which fail to close during pregnancy, and can result in the death of the foetus. Hence, the fortification of cereal grains and other foods with folic acid is mandated by many governments.

The inhibition of dihydropteroate synthase, an enzyme that synthesises tetrahydrofolate, is one of the key mechanisms that antibacterial agents can target. Sulfonamides, which are similar in structure to 4-aminobenzoic acid, the natural substrate, are reversible inhibitors of the enzyme. As a result, insufficient folic acid is produced in bacteria, and they either stop dividing or die. 

This makes sulfonamides seem dangerous - wouldn’t this affect human cells as well? However, bacterial cells produce their own folic acid, whereas human cells do not; instead, we absorb it from our diet, while bacterial cells lack the ability to do so. As a result, sulfonamides selectively kill bacterial cells, leaving our cells intact and healthy.

A Beginner's Guide to Detoxing

For tmphenomenon:

I was looking forward to writing this for you because I love seeing young, black people do things to better their overall health (so we can be fine and sexy forever and slay into eternity, Amen). ALSO, ‘CAUSE, YOU’RE FAM FOR LIFE!!!

Why people detox:

When we enjoy delicious ass shit from our affordable fast food restaurants, we are destroying our body. Most of the time, the food we eat has been fried, dyed, processed, “enriched,” packaged, repackaged, and distributed, so by the time it gets to us it’s not really even food, though it tastes fucking amazing. It really messes with our internal health and perspective, clouding our judgment and fucking up our life. The healthier you eat and drink in general, the more clarity you have.

To combat the nasties, your body needs mini-cleanses every now and then so your digestive system can properly eliminate the bad, allowing for the absorption of good vitamins and nutrients we actually need. This strengthens your immune system and cleanses the blood. It also helps to block certain negative creepy crawlies that try to infect our cells.

The body eliminates toxins via the kidneys, intestines, lungs, skin, and lymph nodes, but most of the time it’s using all of its energy to break down everything we eat. Therefore, the toxins just float around and wreck havoc because the body ain’t got time to kick them out.

Buckle, up! Here we go! 

BODY

Food + drinks:

1. Lots of liquids- this flushes out all the bad stuff. It’s good that you already drink lots of water, but we need to kick that up a notch with herbs that will help cleanse your liver and colon, bettering your overall digestive health. I, of course, being a ratchet hippie, recommend tea. 

 a) infuse water overnight (slices of cucumber or lemon in a bottle). See tumblr for the chart of when is best to drink water for the most benefits + recipes at bottom.

b) green tea or herbal tea, start off with green +honey then work your way up 

c) juice! -fresh, not-from-concentrate, not- bullshit into thinking it’s healthy

You don’t even need a juicer, honestly. pour some water in a blender and spinach in there. BOOM. juice.

2. Fresh fruits and veggies (it’s cheaper to do this in smoothie-form). Big bags of spinach, bananas, and whatever fruit you blended up in a cheap blender (I got my from Wal-Mart for $15 and found another one at Goodwill for 3).

3. Fiber: This will help your body get rid of the toxins easier. I recommend eating at least one of the following ever day: brown rice, sprouted bread (NOTHING “enriched,” that just means bleached to look pretty -__-), cabbage, broccoli, spirulina, chlorella, etc. Fruits and veggies have an ass of fiber, so if you’re already eating those, you’re good.*

*If you don’t want to do the actual work, I recommend Bolthouse farms green juices. They taste good, have no preservatives, and are like 2.35 for 8 servings at Aldi. If y'all don’t have Aldi, I’ll get you some. Also, a lot of people mix these with water to stretch them, but also to make sure your body isn’t overwhelmed.

4. Take some type of vitamin. When I was drunk I ranted about “eating the rainbow,” because different colors correspond to different essential nutrients we need to survive the human experience. These colors also correspond to the 7 chakras. If you’re eating right, it balances other aspects of your life as well. Most of the time ain’t nobody got money or time for that, so buy a cheap one-a-day multivitamin so you won’t shock your body during detox.

What do the colors of fruits and veggies mean? (pic via @catasana)

Blue/purple= high antioxidant + balance bood pressure

Green= remove toxins and carcinogens, also sources of vitamin K, folic acid, omega 3 fatty acids

Yellow= Lutein (good for eyes), healthy fats, pretty skin

Red= powerful antioxidants 

Orange= vitamins A +C

Tans/weird beiges–usually high fiber content

5. Healthy fats- Depending on how long you want to detox, you’ll need to reintroduce heavier foods into your diet, after mostly eating fruits, vegetables, seeds, etc., so you won’t shock your body when you eat a piece of pizza

Try: Salmon, avocados, walnuts, etc.

6. Simply substitute slowly (alliteration for that ass!) Going cold turkey will make you miserable. Instead of french fries, get sweet potato fries. Instead of ranch dressing, get Italian or something oil/vinegar based. Instead of iceberg lettuce (which is honestly trash, and I would slap the fuck out of anyone who tried to serve it to me), get romaine. 

1 month detox:

First week: just drink one green smoothie/drink/tea (or eat your fill of fruit) every morning and don’t change anything else. Soon your body will start to crave whatever is in your smoothie.

You can also alternate between a green smoothie, a scrambled egg on toast w/ avocado, or BOTH. Whatever else you want that’s not like… frosted flakes you can pretty much have. You just want you body to get into a routine. Avoid heavy, delicious foods like pancakes, pasta (anything wheat-based. we’re prepping your digestive system) and no candy +sugar.

Second week: Make your breakfast AND lunch “green.” Have a big ass salad or lots of vegetables with a side of sweet potatoes or something. NO CHEESE (feta/goat cheese is okay though–easier for body to digest and less allergenic). We’re not even supposed to have dairy products, because it doesn’t agree with our systems at all, plus it’s gross (but so delicious).

I tell non-vegetarians that it’s okay to have chicken and lighter choices, but stay away from beef and dairy products. Listen to your body. Once it’s detoxing, you’ll start to crave everything you DON’T need to have. Especially sugar. Pretty much any fast food we eat is jacked up on sucrose. 

The first 2-3 days you might feel super crappy because your body is ridding yourself of toxins, but  once you get past that you’ll have an unusual amount of energy.

Third week: If you made it past the cravings hurdle, up the ante. Have a green juice before bed as well as in the morning. Stick with your one green meal for lunch or dinner. It is important that you eat enough, otherwise you will feel weak. Plants and herbs give you a lot of energy but you need to EAT them and drink them. We feel full after eating a burger but lethargic the next day because we just poisoned our body. We feel awesome after having a big ole salad because we basically just ate direct sun energy.

Last week: Listen to your body. The first time I did any kind of detox, I was so eager to stick to a plan, but every plan doesn’t work for everybody. Your body will tell you what it needs and by this time you’ll know what it is you’re supposed to be eating and drinking. It takes 21 days to break a habit (I don’t know if this is true, but let’s go with that).

Also, your body might not need a full month, and it might need longer than a month. You can tell how you’re doing by your energy level, whether or not you had a detox reaction (the feeling crappy, almost flu-like), and if you’re shitting regularly. 

Common types of detoxes:

Some people detox for weight loss, health issues, or just want to give their bodies a break. From what I’ve experienced, here are the most popular types:

1) Strictly juicing/liquids: unfeasible for you because you’re on your feet all day or using your energy on snapchat. The longest I’ve seen someone do a juice cleanse is for 41 days, but usually they’re 3-5, just to give your body a break)

2) All green- basically, no animal products and not a lot of processed food. Plant-based/(80/20 raw/cooked) are common forms. If you eat pasta/fries/pizza, you make it yourself and know all the ingredients going into it. Be cheap and buy frozen fruits and vegetables and make stir fry. Whatever you want to learn how to make, check out organigasm’s instagram and I’ll send you the recipe. It doesn’t have to be flavorless and fucking boring to be healthy.

3) Paleo- Yes: Fruits, Vegetables, Seafood, Nuts & Seeds, Healthy Fats, Lean Meat. No: Dairy, Grains, Processed Food, Processed Sugar, Legumes, Starches, Alcohol. Honestly, I think this diet is a fad that comes up with different names every few decades. Seriously, a bunch of rich people use this to diet or have “healthy lifestyles,” but thousands upon thousands of families don’t have access to these types of foods. I digress.

MIND:

1. Set your intentions when you wake up in the morning. Example: “Today, will be fan-fucking-tastic,” or you can thank the creator or thank your body for helping you out with your shenanigans. Keep it to yourself, write it down, shout it out, whatever. You need to start your day with positive thoughts to ensure you have the willpower to make it. You will crave everything you DO NOT need.

2. Work-out at least 30 minutes a day, and if you can’t do that, try 3/7 times a week. Start somewhere. Dance it out when you get out of the shower, walk down the street at a fast pace–whatever, again, just get moving.

3. For strength of body and mind, I recommend yoga, and I hope your stubborn ass considers it (it also makes for fun sex, I’m just saying).

Here’s a link to good poses for detoxing: http://bodyunburdened.com/yoga-for-detox-10-poses-that-promote-cleansing/ + youtube and netflix have free videos FOR NOOBZ!#@

4. Before you go to bed, clear all the negative energy you can. I’m not gonna get into all the stuff, but like when you woke up, write it down, draw it out, etc.

Doing this throughout the detox will allow you to clear your mind and determine what works for you during this new journey!

5. Get enough sleep–This is a tough one, but while you’re sleeping your body does the most incredible things. Seriously, you will thank yourself. Even if you only get 4 hours of sleep, getting 15 extra minutes, then gradually increasing REALLY helps.

Final tips:

1. eat your biggest meal at lunchtime (your metabolism is peaking from about 12pm-8pm)

2. SLEEP. Seriously. Your body is healing you. Let it help.

3. I will help you meal prep, but frozen vegetables + canned beans, packaged nuts keep the costs of detoxing low. Also, farmer’s have good ass prices. Take a fine honey on a date to the farmer’s market and cook a sexy meal afterwards.

4. Try new things. Seriously. You can’t eat a cucumber and an apple every day and expect magic to happen. 

5. Don’t overcook anything. Leave that broccoli a little crunchy. Don’t kill the nutrients, bro.

6. cheat! allow yourself one day during the first two weeks to cheat on your detox, or whenever you fucking feel like. you deserve rounds… of krispy kreme donuts. TREAT. YO. SELF. 

7. Don’t count calories, or carbs, or whatever the fuck the newest pyramid says to do. 

Good Water Infusion Combos:

1. lemon/lime +mint + honey

2. strawberries, blueberries

3. pineapple + basil

4. grapefruit/orange

5. mango + peaches

6. apple+ cinnamon + honey 

Final thoughts: Really, once you get used to it, you’re always detoxing. Even drinking a cup of tea a day and still eating like shit is better than nothing.  Just be kind to yourself. It’s a process, and I’m still learning, but I get better every day. Good luck! I’m always here to help. 

Now, let’s go detox, y'all.

✌️

#pepperonyweek17 - day 7

“We are kinda - well, not kind of -”

“Pregnant?”

No, definitely not.” “Well, yeah.”

A grin split Steve’s face and he leaned across the table to pump Tony’s hand enthusiastically. “Congratulations!”

“Are you going to sign the-”

“Forget about those, Tony, you’re going to have a kid!”

“Steve, I-”

“Get your lawyers to deal with it. That’s what you pay them for, right?”

“But-”

“When’s the due date?”

Tony sighed. “October.”

Keep reading

What I have learned about growing out a pixie cut:

-every hairdresser and hair expert is going to tell you to get a trim every 6 weeks or so. DO NOT LISTEN.
-instead of getting a trim to cut off the dead ends, just avoid dead ends in the first place. And yes, I’m talking about not using heat on your hair.
-heat is a no go when it comes to growing out a pixie. I only straighten mine once every 4 weeks to keep you guys updated and to see my growth and compare pictures.
-avoid using products such as hairspray, mouse, gel, etc. they dry your hair out, so if you are going to use anything, use small amounts.
-don’t wash your hair unless you have to. Unless your hair physically feels dirty, don’t wash it. Trust me, your hair won’t smell, nobody will know it’s not washed.
-play around with different styles. If you don’t find hairstyles you like you’re going to dread the grow out process.
-try to put your hair in a ponytail every few weeks. It’s a good way to mark your progress. You’ll start to notice your ponytail getting longer and less and less pieces will hang down as time goes by.
-once you can make a decent ponytail mess around with making buns. I can remember wishing to be able to make a bun and now I can make a little one
-always remember, baby steps! Your hair goes through a lot and it can only grow so fast. Be happy with your progress and have fun with it.
-lastly, vitamins! I can’t stress enough how much improvement I saw in my hair after I started taking vitamins. I take prenatal vitamins and folic acid for my hair growth. I take fish oil too, but that’s for my joints. I would suggest biotin too if it’s in your budget. Prenatal vitamins do the trick though!

Hope this helps!

Hey everyone, I haven’t posted in awhile but I just realized something very important that I need to share.

I switched from biotin to folic acid this year because it was easier o=to find a cheaper but I’m regretting it now because I’ve realized I’ve been taking a very unhealthy dose that could be the reason for a lot of the weird symptoms I’ve been experiencing lately. You shouldn’t be taking more than 1000mcg/1mg a day and I had been taking 2mg/2000mcg!! I’m going back to biotin because there really is no unhealthy amount known yet, so it’s a lot safer and honestly I had better results. 

I’m so sorry for steering any of you into the wrong direction but I’m standing by Biotin from know on

Happy Growing! 

MTHFR does not mean mother f*cker (or does it)

I’m never one to shy away from telling someone “I told you so."  So it’s no surprise after the phone call I just received that I’m flailing my arms about and pointing and repeating it over and over again.

I told you so. 

The nurse just called and confirmed the sensation I’ve had in every ounce of my being since April.  There is another potential cause for my recurrent losses.  I have a MTHFR mutation (specifically she said a C677C mutation).  While it may not have been the sole cause for miscarriage, it could have been and it definitely could have contributed.

I’ve only started my MTHFR research, but the things that they are saying about it make perfect f*cking sense.  I’ve known for a few years that I have a B12 deficiency and problems absorbing B12.  MTHFR mutations are also responsible for depression and other things that I’ve experienced in my life. 

So now they’re putting me on Folgard (high dose folic acid) and once we have a positive pregnancy test again, they’ll start me on heparin. 

I knew I wasn’t crazy.  I just knew it. 

Any resources that people have would be much appreciated. 

While researchers don’t know why folic acid helps prevent birth defects, it has been shown to decrease the risk of the most common NTDs (Neural Tube Defects): spina bifida (the leading cause of childhood paralysis) and anencephaly (a fatal condition in which an infant is born with a severely underdeveloped brain and skull).

Not only does folic acid combat these NTDs, but it may also help keep your baby from developing a heart defect, cleft lip, or cleft palate.

Additionally, a pregnant woman needs folic acid to help support the rapid growth of the placenta and fetus. The nutrient aids in baby’s DNA production. Cell division and fetal growth can become impaired without it. One study found that women with folic acid deficiencies were two to three times more likely to have a premature baby or a baby of low birth weight than those who got enough of the vitamin.

Anti-epileptics/Anti-convulsants Made Incredibly Easy

TREATMENT STRATEGIES:

  • Start therapy after the second seizure; first ONLY if recurrence is high = MRI abnormal, EEG abnormal, or status epilepticus.
  • Monotherapy until seizures are controlled.
  • If failed: titrate up to maximum tolerated dose –> shift to alternative drug –> use drug combination –> VNS, DBS.
  • Full drug therapy for 2 – 3 years after the last fit.
  • Gradual withdrawal over at least 6 months.

Rx Profile:

(Drawings are courtesy of @mynotes4usmle​)

Carbamazepine

  • Mainly for generalized tonic-clonic seizures
  • Trigeminal neuralgia
  • Bipolar disorders (with depressive predomince) - mood stabelizier
  • NEVER in abscence seizures
  • SE:

Lamotrigine

  • Safer profile, with minimal interactions.
  • Bipolar disorders (with depressive predominance) - mood stabilizer  
  • SE: maculopapular rash; SJS

Topiramate

  • Broad spectrum anti-seizure; used in migraine.
  • SE of TopIRamate: enzyme Inhibitor + Renal stones.

TREATMENT PROTOCOL:

Green: first line; Yellow: second line; Orange: third line; Red: contraindications. (Graph reproduced from Oxford Handbook of Clinical Medicine)

Epilepsy & Pregnancy:

  • Non-enzyme-inducing AEDS have no effect on the pill. Enzyme inhibitors prolong the half life of OCP (=Valproate) so better for birth control , and vice versa.
  • Most of AEDs are teratogenic; Category D
  • Therapy not stopped; uncontrolled seizure is risky to fetus & mother. Give lowest effective dose.
  • Avoid phenytoin, valproate and barbiturates (use Lamotrigine)
  • Most AEDs cause folate deficiency …. Folic acid (prior to or early in conception)
  • Most AEDs are competitive inhibitors of vit. K-dependent clotting factor: Vit. K to mother 10 days before labor & to newborn.
  • Most except carbamazepine and valproate are present in breast milk. Lamotrigine is safe on infants.

Status Epilepticus:

  • WHAT? Seizures lasting for >30min, OR repeated seizures without intervening consciousness.
  • Things to be done:
  1. Bedside glucose, the following tests can be done once Rx has started: lab glucose, ABG, U&E, Ca2+, FBC, ECG.
  2. Consider anticonvulsant levels, toxicology screen, LP, cultures, EEG, CT, CO level.
  3. Pulse oximetry, cardiac monitor.
  • How to treat?

THE END

Originally posted by disneypixar

3

Allison gasps: A blood transfusion? For anemia? I’m sorry but I don’t understand, Dr. French. I also have anemia, and I’ve been pregnant, and I was told to take prenatal vitamins.

Dr French nods: Yes, most mild to moderate anemia can be treated with vitamins, folic acid. But Lala has severe anemia. Her hemoglobin count is dangerously low. We can wait until she reaches the latter stage of pregnancy to discuss a transfusion, but honestly, I’m concerned and I’d like to treat it as quickly as possible. I’m concerned about possible heart failure. 

Remy overwhelmed: Heart failure?

Dr. French: Anemia can cause the heart to pump more blood which enlarges the heart. Plus, Miss Reyes’ pregnancy will be very difficult …she’ll be fatigued,disoriented. 

Remy: Sepsis and heart failure and blood transfusions, I just don’t get it. She just seemed real tired, not like she had all this going on.

Nico: Dr. French, how soon can she start a transfusion if you think it necessary?

Dr French frowns: That’s the worrisome part. Lala has an extremely rare blood type. One of the rarest ever. I don’t know how soon we can find a matching donor. If at all. 

dragondez90  asked:

Have you done any thing about Rhodesian ridge backs? I haven't seen anything!!

That is because you have been waiting very patiently in the queue. (It is a long queue)

The Rhodesian Ridgeback seems to be an increasingly popular breed, which suffered a bit of heat after Pedigree Dogs Exposed because of the then common practice of euthanizing puppies born without the ridge. (You might remember a breeder chastising ‘young’ vets who refused to do this for her, even though it was a show fault). It’s claimed that this happens less often, but I can’t say I’ve seen any ridgebacks without a ridge, and the trait is thought to be as common as 10% of pups born, so I don’t know what’s really happening out there.

But first, please note the disclaimer that these posts are about the breed from a veterinary viewpoint as seen in clinical practice, i.e. the problems we are faced with. It’s not the be-all and end-all of the breed and is not to make a judgement about whether the breed is right for you. If you are asking for an opinion about these animals in a veterinary setting, that is what you will get. It’s not going to be all sunshine and cupcakes, and is not intended as a personal insult against your favorite breed. This is general advice for what is common, often with a scientific consensus but sometimes based on personal experiences, and is not a guarantee of what your dog is going to encounter in their life.

(Ridgeback Image source)

Generally structurally sensible dogs, the ridge of reverse fur along their spine has long been the trademark of the breed. An individual dog can be perfectly happy and healthy without it, just like every other non-ridgeback dog on the planet, but healthy puppies were traditionally euthanised if they didn’t have the ridge.

Puppies with Dermoid Sinus were traditionally euthanised too, though more are probably having surgery these days. A dermoid sinus is an embryonic abnormality. The tissue which goes on to become the skin and the spinal cord don’t completely separate, so you end up with a sinus which starts at the skin and may go as deep as the spinal cord. It can cause meningitis or myelitis. resulting in pain and suffering for the dog. There is an association between having a ridge and developing dermoid sinus, but folic acid supplementation in pregnancy also seems to be at least partially protective. It’s been suggested that this condition could be prevented further by breeding ridged dogs to ridgeless dogs instead of always breeding ridged to ridged.

Like many large breeds, hip dysplasia is a concern in the breed. A small number also go on to develop degenerative myelopathy and it can be difficult to distinguish between thr two conditions without Xrays.

Entropion is the most commonly seen eye problem in this breed, but at least the breed hasn’t been actively selecting for it.

I see hypothyroidism reasonably commonly in ridgebacks, and it seems to be associated with lymphocytic thyroiditis. It’s perfectly manageable, but can be slow to notice and diagnose.

Another trend I see, which I have no explanation for, is unusual, benign skin tumors. These relatively rare tumors of kinds I was fairly unfamiliar with that seem to be more common in this breed. They’re cured surgically.