The 2015 Nobel Prize in Chemistry
Tomas Lindahl, Paul Modrich, and Aziz Sancar for mechanistic studies of DNA repair.
Oxford University Press is proud to publish the work of many Nobel Prize winners, including Tomas Lindahl, Paul Modrich, and Aziz Sancar.
- “Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice” by Marcel Osterod et al in Carcinogenesis
- “Hydrolytic function of Exo1 in mammalian mismatch repair“ by Hongbing Shao et al in Nucleic Acids Research
- “Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks" by Junhua Zhao et al in Nucleic Acids Research
- “Highly specific and sensitive method for measuring nucleotide excision repair kinetics of ultraviolet photoproducts in human cells” by Jun-Hyuk Choi et al in Nucleic Acids Research
- “RNA polymerase II stalled at a thymine dimer: footprint and effect on excision repair” by Christopher P. Selby et al in Nucleic Acids Research
- “Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein” by Tae-Hong Kang et al in Nucleic Acids Research
- “Rodent UV-Sensitive Mutant Cell Lines in Complementation Groups 6–10 Have Normal General Excision Repair Activity” by Joyce T. Reardon et al in Nucleic Acids Research
- “The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD” by Laura A. Lindsey-Boltz et al in Nucleic Acids Research
- “Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA” by Jun-Hyuk Choi et al in Nucleic Acids Research
- “DNA Repair: Enzymatic Mechanisms and Relevance to Drug Response” by Stephen G. Chaney and Aziz Sancar in JNCI: Journal of National Cancer Institute
And Tomas Lindahl wrote his own entry in Who’s Who (tip: he likes piano, wine, and modern art).
For a greater understanding of DNA repair, check out
- Structural Biology of DNA Damage and Repair, edited by Michael Stone (American Chemical Society)
Congratulations Tomas Lindahl, Paul Modrich, and Aziz Sancar!