Some people say that you find that romantic “spark” when you encounter someone who compensates for your own flaws. By doing so you can find an idealized version of a personality completely opposite to yours, through a romantic relationship. In a nutshell, you’re trying to get rid of the self you hate through romance.
Here the art book for Catherine refers to Erica, a trans woman, as Eric. It also seems to list her sex as male.
Additionally, in Catherine, Erica is insulted by her alleged friends, who accuse her of not being a real woman. She is given nightmares exclusively given to men. The nightmares themselves are punishment for not revealing that she was trans to one guy she slept with.
Beyond that, a character in the game also says that sex with Erica was “weird”.
All in all, the game is thoroughly transphobic and deserves no praise for its representation of trans women.