Audrey Hepburn in Wait Until Dark (Terence Young, 1967). She plays a blind woman who must fight off attackers in her apartment.
This was Hepburn’s last film - and the last of her 5 Oscar nominations - before taking a 9 year break from films to spend more time with her family. She returned in 1976 co-starring with Sean Connery in Richard Lester’s Robin and Marian.
Audrey Hepburn in her final Oscar-nominated performance as Susy Hendrix, a blind woman unwittingly in possession of a coveted heroin doll, in Wait Until Dark (1967, Terence Young; pictured with Alan Arkin)