Favorite Season is 3, but my favorite episode has to be Amnesia from Season 1. I love these kinds of things, where a main character forgets everything, it’s gotta be my favorite trope. Have a quick story.
I remember the day you told me you were leaving
I remember the make up running down your face
The dreams you left being you didn’t need them
Like every single wish we ever had
I wish that i could wake up with amnesia
Forget about the stupid little things
Like the way it felt to fall asleep next to you
and the memories i never can’t scape
‘Cause i’m not fine at all
i remember the day you told me you were leaving, i remember the make-up running down your face. and the dreams you left behind you didn’t need them, like every single wish we ever made. i wish that I could wake up with amnesia, and forget about the stupid little things. like the way it felt to fall asleep next to you, and the memories I never can escape.
Amnesia Dreamy Summer Body Pillow Case
Ever dreamt about taking a nap with 5
beautiful men on a hot summer day? Now you can! A body pillow will fit
perfectly in this pillow case, which secures with a zipper. You don’t
need to look elsewhere for a sweet dream when you nap or sleep at night!
Size: Approx. 47 inch x 20 inch
*Body Pillow is not included.
Delve deeper into the world of Amnesia!
With every page you turn, you’ll be greeted with character art, rough
sketches, concept art, special illustrations, and more!
Approx. size: 7 inch (h) x 5.5 inch (w)
Amnesia Soundtrack CD
Recreate the scenes of Amnesia: Memories with this background music CD!
Pack up your memories in this collector’s box!
Memories that have been “lost” as a result of amnesia can be recalled by activating brain cells with light.
In a paper published in the journal Science,
researchers at MIT reveal that they were able to reactivate memories
that could not otherwise be retrieved, using a technology known as
The finding answers a fiercely debated question in neuroscience as to
the nature of amnesia, according to Susumu Tonegawa, the Picower
Professor in MIT’s Department of Biology and director of the RIKEN-MIT
Center at the Picower Institute for Learning and Memory, who directed
the research by lead authors Tomas Ryan, Dheeraj Roy, and Michelle
Neuroscience researchers have for many years debated whether
retrograde amnesia — which follows traumatic injury, stress, or diseases
such as Alzheimer’s — is caused by damage to specific brain cells,
meaning a memory cannot be stored, or if access to that memory is
somehow blocked, preventing its recall.
“The majority of researchers have favored the storage theory, but we
have shown in this paper that this majority theory is probably wrong,”
Tonegawa says. “Amnesia is a problem of retrieval impairment.”
Memory researchers have previously speculated that somewhere in the
brain network is a population of neurons that are activated during the
process of acquiring a memory, causing enduring physical or chemical
If these groups of neurons are subsequently reactivated by a trigger
such as a particular sight or smell, for example, the entire memory is
recalled. These neurons are known as “memory engram cells.”
In 2012 Tonegawa’s group used optogenetics — in which proteins are
added to neurons to allow them to be activated with light — to
demonstrate for the first time that such a population of neurons does
indeed exist in an area of the brain called the hippocampus.
However, until now no one has been able to show that these groups of
neurons do undergo enduring chemical changes, in a process known as
memory consolidation. One such change, known as “long-term potentiation”
(LTP), involves the strengthening of synapses, the structures that
allow groups of neurons to send signals to each other, as a result of
learning and experience.
To find out if these chemical changes do indeed take place, the
researchers first identified a group of engram cells in the hippocampus
that, when activated using optogenetic tools, were able to express a
When they then recorded the activity of this particular group of
cells, they found that the synapses connecting them had been
strengthened. “We were able to demonstrate for the first time that these
specific cells — a small group of cells in the hippocampus — had
undergone this augmentation of synaptic strength,” Tonegawa says.
The researchers then attempted to discover what happens to memories
without this consolidation process. By administering a compound called
anisomycin, which blocks protein synthesis within neurons, immediately
after mice had formed a new memory, the researchers were able to prevent
the synapses from strengthening.
When they returned one day later and attempted to reactivate the
memory using an emotional trigger, they could find no trace of it. “So
even though the engram cells are there, without protein synthesis those
cell synapses are not strengthened, and the memory is lost,” Tonegawa
But startlingly, when the researchers then reactivated the protein
synthesis-blocked engram cells using optogenetic tools, they found that
the mice exhibited all the signs of recalling the memory in full.
“If you test memory recall with natural recall triggers in an
anisomycin-treated animal, it will be amnesiac, you cannot induce memory
recall,” Tonegawa says. “But if you go directly to the putative
engram-bearing cells and activate them with light, you can restore the
memory, despite the fact that there has been no LTP.”
Further studies carried out by Tonegawa’s group demonstrated that
memories are stored not in synapses strengthened by protein synthesis in
individual engram cells, but in a circuit, or “pathway” of multiple
groups of engram cells and the connections between them.
“We are proposing a new concept, in which there is an engram cell
ensemble pathway, or circuit, for each memory,” he says. “This circuit
encompasses multiple brain areas and the engram cell ensembles in these
areas are connected specifically for a particular memory.”
The research dissociates the mechanisms used in memory storage from
those of memory retrieval, according to Ryan. “The strengthening of
engram synapses is crucial for the brain’s ability to access or retrieve
those specific memories, while the connectivity pathways between engram
cells allows the encoding and storage of the memory information
itself,” he says.
Changes in synaptic strength and in spine properties have long been
associated with learning and memory, according to Alcino Silva, director
of the Integrative Center for Learning and Memory at the University of
California at Los Angeles. “This groundbreaking paper suggests that
these changes may not be as critical for memory as once thought, since
under certain conditions, it seems to be possible to disrupt these
changes and still preserve memory,” he says. “Instead, it appears that
these changes may be needed for memory retrieval, a mysterious process
that has so far evaded neuroscientists.”
On February 1, 2015, a woman currently known as Sam was found in Southern California in very serious condition. Sam was rushed to the hospital and spent some time in the ICU. It was discovered that she had a tumor the size of a volleyball in one of her ovaries and the tumor had caused her to suffer retrograde amnesia. Sam has no idea who she is or where she is from. She has an accent that is likely Australian and she has managed to keep memories of Perth and Queensland in Australia among various other places and she says she has dreamed of a home in Hawaii and that Hawaii and Australia both feel very familiar to her.