ebola virus

Remember Dr. Ian Crozier, the NYC doctor infected with Ebola last October? Of course you do! Well, apparently, less than two months after the medical team that treated him thought him cured, “he was back at the hospital with fading sight, intense pain and soaring pressure in his left eye.”

Dr. Crozier’s left eye, pictured above on the right, was teeming with Ebola. 

From the article, “By the time [Crozier] left Emory, his blood was Ebola-free. Although the virus may persist in semen for months, other body fluids were thought to be clear of it once a patient recovered. Almost nothing was known about the ability of Ebola to lurk inside the eye.”

Read more at the link!

Ebola Situation Report - 22 April 2015

SUMMARY

  • The decline in confirmed cases of Ebola virus disease (EVD) has halted over the last three weeks. To accelerate the decline towards zero cases will require stronger community engagement, improved contact tracing and earlier case identification. In the week to 19 April, a total of 33 confirmed cases was reported, compared with 37 and 30 in the preceding weeks.
  • In the week to 19 April, Guinea reported 21 confirmed cases, compared with 28 cases the previous week. Sierra Leone reported 12 confirmed cases, compared with 9 cases reported the previous week. Liberia reported no confirmed cases.
  • A total of 4 Guinean prefectures reported at least one confirmed case in the week to 19 April, compared with 5 the previous week. Transmission remains confined to the west of the country and is primarily focused on the prefecture of Forecariah, bordering Sierra Leone, which reported 86% of national confirmed cases.
  • In Sierra Leone, Western Area Urban, which includes the capital Freetown, reported 6 confirmed cases, which represent half of the cases reported nationally, a slight increase from 4 cases the previous week. Koinadugu, which borders Guinea to the north, reported 1 new confirmed case of unknown origin. Other districts reporting new confirmed cases were Kambia (4 cases) and Port Loko (1 case) in the west of the country. In the week to 19 April, 4 districts reported at least one confirmed case compared to 3 districts the previous week.

(More from WHO)

24 April 2015

Banishing Ebola

The Ebola outbreak in West Africa is still ongoing, with over 24,000 recorded cases and no licensed treatment or vaccine. Understanding how the body interacts with – and attempts to fight – the virus is key to developing effective vaccines. B- and T-cells are the body’s defence against disease – when they find infection they will multiply and attack. Importantly, these immune cells will ‘remember’ the illness, creating immunity to re-infection. Until now it was believed that the Ebola virus (pictured) was an immunosuppressant, which limited the body’s ability to fight back in this way. But monitoring the response of B- and T-cells in four patients infected with Ebola showed that there was significant B- and T-cell activation, with particularly large proportions of CD8-type T cells. These T cells targeted specific proteins on the virus, suggesting that medicine containing these proteins will activate the production of CD8 T cells, providing effective future vaccination against Ebola.

Written by Helen Thomas

Image by Cynthia Goldsmith and Pierre Rollin
Centers for Disease Control and Prevention, USA
Originally published under a Creative Commons Licence (BY 4.0)
Research published in PNAS, April 2015

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To everyone angry that people are thanking God that the Ebola outbreak is over...

Hello, future doctor here. Thank You God that You helped the doctors and health care workers contain and stop this outbreak. Thank You God for saving those that You did. Thank you God for giving the doctors, nurses, and other health care workers the hearts and brains that they have. Thank You God for stopping this disease.

3

The toll of a tragedy 

THE first reported case in the Ebola outbreak ravaging west Africa dates back to December 2013, in Guéckédou, a forested area of Guinea near the border with Liberia and Sierra Leone. Travellers took it across the border: by late March, Liberia had reported eight suspected cases and Sierra Leone six. By the end of June 759 people had been infected and 467 people had died from the disease, making this the worst ever Ebola outbreak. The numbers keep climbing. As of March 15th 2015, 24,701 cases and 10,194 deaths had been reported worldwide, the vast majority of them in these same three countries. 

The outbreak continues to claim lives, but Liberia has no confirmed new cases for the third week in a row. The situation in Guniea is causing more concern with a low proportion of cases emanating from known contacts and many ebola related deaths being confirmed post-mortem. However, the World Health Organisation reports that each country now has enough treatment beds to be able to isolate and treat patients with Ebola, and to bury everyone known to have died of the disease. The chart above shows numbers from both the WHO’s regular situation reports and from patient databases, which tend to be more accurate but are less complete for recent weeks.

(More from The Economist)

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futurity.org
Are statins the secret weapon against Ebola? - Futurity
Last September, 100 patients with Ebola were given statins. All but two reportedly survived. So why are researchers calling the experience "disappointing"?

We had reports about 100 patients who received this combination, and we got glowing preliminary reports but we never got final data. In all candor, I do not know how effective this is or not. We’re still hoping we will get a final report. This is hugely disappointing.

The data may still be sitting there but we don’t have that information. I don’t wish to imply that we’re confident with the results. It shows the difficulties, if you are not physically there, and are relying on other people who have other priorities, and we didn’t have any money. It was incredibly frustrating.

We’re left with the idea. It seemed like a good idea in September and we still think is a good idea—and there is some animal data to support it. But that’s basically it.

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In a district of South Freetown, Sierra Leone, 60 people have been quarantined for 21 days because a person in their neighborhood tested positive for Ebola. 

We are on the ground delivering Quarantine Kits to people - watch the video to find out how they are helping.

Ebola epidemic: Ebola Virus Symptoms when infected Ebola

Ebola Virus Symptoms disease?

According therapy hemorrhagic fever caused by the Ebola virus of the Ministry of Health, the clinical symptoms of Eboladisease in the incubation period of 2-21 days include: acute fever, headache, muscle fatigue, nausea, vomiting, diarrhea,abdominal pain and conjunctivitis.

In addition, patients also expressed rash. Initially sold as dark as red pins concentrated in hair follicles, after initial lesionformation is abundant and final boundaries of the original spread, usually in the first week of illness.

Besides, bleeding is one of the symptoms of Ebola, including black stools, bleeding where infusion, coughing blood, toothbleeding, hematuria, and vaginal bleeding.

In an outbreak of dengue fever caused by Ebola virus, the subjects at high risk of virus infection include:

– Hunters, who live in the woods in contact with sick or dead animals: chimp, ape, monkey forest, antelope, porcupines,fruit bats …

– Family members or those who have close contact with sick people.

– Staff funeral, funeral participants have direct contact with the patient‘s body.

– Medical personnel direct patient care.

After contact with infected or suspected Ebola virus or the appearance of disease symptoms, you should immediately go to the nearest medical treatment, medical care in order to reduce the risk of death.

Pandemic Ebola outbreak is still strong in the West African nation. According to statistics from the Ministry of Health, as of now, the disease caused by the Ebola virus has claimed the lives of nearly 5,000 people in a total of nearly 14,000 cases.