drug label

Blacks often get labeled as drug dealers since they make up majority of the prison population. People often tell blacks that they’d stop getting incarcerated if they’d stop selling drugs. Research shows that more whites sell illegal drugs than blacks, yet, blacks are arrested more often. That’s something many blacks should bring up.

Another thing to remember is that blacks aren’t the real drug dealers. Illegal drugs arrived in the black communities through President Reagan and the CIA to fund the war in Nicaragua. It was also to end activity by the Black Panther Party. How ridiculous is a president selling a dangerous drug to his country to battle another country? When people say blacks are true drug dealers, remind them of Reagan and the CIA. Think of the amount of drugs it takes to fund a war.

Let's Talk About COX

Everyone has some kind of NSAID in their medicine cabinet whether it be Advil, Aleve, or Aspirin. These drugs are so common that they are often not even considered drugs and so people freely take more than they should or give them to their pets. Understanding how these drugs work not only helps explain why the directions for using them are so specific, but also shows how really amazing it is that we even have them. So, let’s get to the real reason you are here- COX.

Animal and human cells are sort of like water balloons. The “balloon” part of the cell is the membrane which is made up of lipid molecules. The water is actually still water but also filled with lots of different organelles, proteins, enzymes, and other things that make the cell work. Located within the cell membrane is a special lipid called arachidonic acid (AA). Usually AA just hangs out in the membrane not doing a whole lot. It takes an enzyme called phospholipase A2 (PLA2) to free the AA from the cell and let it get to work.
PLA2 is itself “turned on” by other enzymes but to make it simple, it is activated when there is an injury of some kind. It breaks the AA free of the cell membrane so that it can then be turned into other useful molecules.

Usually AA can be turned into three different types of molecules: prostanoids, leukotrienes, and epoxides. We are only going to worry about prostanoids today.
Prostanoids are a group of molecules that do lots of different things in the body including create inflammation, dilate blood vessels, activate platelets, de-activate platelets, protect the GI tract, make sure the kidneys have enough blood flow, and other important for living type things.

Here is where the COX comes in. COX-1 and COX-2 are enzymes that convert arachidonic acid into usable molecules. In very general terms COX-1 is responsible for making housekeeping type molecules, the ones that protect the gut and keep the kidneys working. COX-2 is the enzyme that makes the inflammatory molecules. In reality it isn’t that simple and box COX enzymes overlap in function but we are keeping it simple.
COX converts AA into PGH2 which is then further into five different prostanoids, Thromboxane, PGD2, PGI3, PGF2, and PGE2. The prostanoid we care about right now is prostaglandin E2 (PGE2). PGE2 is an inflammatory mediator and is responsible for the classic signs of inflammation: redness, swelling, pain, and warmth or if you wanna impress your friends using Latin: rubor, tumor, dolor, and calor.

PGE2 has four different receptors that it can bind to, each one doing something a bit different. EP4 is the receptor responsible for causing pain and inflammation.

*Head explosion* I know, it is a lot. Let’s summarize. Injury causes PLA2 to free arachidonic acid from the cell membrane. COX-1 and 2 convert AA into PGH2. PGH2 turns into PGE2. PGE2 binds to receptors on cells which then cause inflammation and pain.

Now we can discuss medications. Corticosteroids like prednisone work by blocking PLA2 way at the beginning of the pathway. This means everything downstream is stopped. There is no production of prostanoids, leukotrienes, or epoxides. Steroids are like bringing a bazooka to a knife fight, they work but there is a lot of collateral damage. We cannot use steroids for very long because of the severe side effects they cause.

NSAID’s are COX blockers. Some block both COX-1 and 2, others are more selective and mostly block COX-2. This prevents formation of PGH2 which prevents all of the prostanoids down stream from being formed. Celebrex was a popular human NAID that preferentially blocked COX-2 which sounded great. However it prevented the formation of PGI2 which was a vasodilator and anti-thrombotic, this caused many people to die of heart attacks. This doesn’t seem to be an issue in pets but blocking COX does lead to GI ulceration and renal damage in some animals. Aspirin irreversibly binds to platelets and prevents clotting which can be a problem in humans and animals in addition to causing GI ulcers.

A fairly new class of drugs called Piprants has been developed and they specifically target one of the receptors that PGE2 binds to. This leaves all of the other molecules available to do their jobs and only prevents pain and inflammation. This means the drug is safe for dogs with liver or kidney disease and shouldn’t have any GI side effects. Hopefully something similar for humans is produced as well.

So that in a very complex nutshell is how NSAID’s work and hopefully now you have a greater understanding of just how important it really is to follow all drug labels. And you now you can tell all your friends about your COX.

*Disclaimer- NEVER give OTC pain meds to your pets. Many are toxic to them and the safe ones require different doses than what humans take. Always consult with your vet first.

The acceptance that there’s room for you in this world, there’s room as a human being, in the state that you are in now. Because this need to fix people all the time, and that’s why I’m kind of rejecting a bit when it comes to treatment, because this need to fix someone, because then it needs to be defined, what is it that needs to be fixed, how quickly should it happen. And what I didn’t get and what I really think would have helped me to get was to get the acceptance that with these feelings, you are still a full human being, and there is room for you.
—  Metta Ellingsdalen, Leaving Psychiatric Labels and Drugs
my ocs as dril tweets
  • Nate: see this watch? i got it by Crying. my car? crying. my beautiful Wife? Crying. My perfect teeth? Crying. now get the fuck out of my office
  • Laurie: i am notr, nor ever have been, a nerd, and i have used some very powerful swear words on this website that would blow most nerds socks off
  • Dave: so long suckers! i rev up my motorcylce and create a huge cloud of smoke. when the cloud dissipates im lying completely dead on the pavement
  • John: *rides a segway through a monolith labeled Drugs & Alcohol , destroying it*
  • Gabe: (flips wallet up in the air and tries to catch it in a cool way but spills its contents all over th e place ( $2))
  • Owen: i just looked up the stats and the number of meaningful relationships ive formed is less than the number of public restrooms ive Screamed in
  • Vivian: "RESULT: You are the Serpant. YOu dislike loud places and people are constantly putting drama in your life. But you're strong." This is true
  • BC: i thjink i'd know the difference between Satan and a noisy washing machine with "666" spraypainted on the side
  • Toby: THis is not a "Meltdown". Its a normal opinion
  • Holly: half wit bumpkin here, looking for new snacks
  • Chuck: i call evbery four-legged animal I see a dog and I am correct more often than not so I will never stop
  • Leon: im an exhausting person to be around but once you get to knnow me im actually a giant shithead with irredeemable mouth
  • Jude: the bird bath institute considers any stone bowl between the size of 8 to 40in. to be a bird bath and they are sick of people disputing this
  • Cynthia: committing unforgivable crimes against nautre in my laboratory ,trying to create the next genetically discombobulated meme animal
  • Mercedes: the human mind... perhaps the most powerful weapon. second only to the "GUN"

anonymous asked:

Quick question about your "curse on white pride" post; whats so wrong about being white and being proud of your heritage? Veneration of ancestors is a huge part of heathenry, so why attack someone because they have white ancestors and aren't ashamed?

okay. fine. i’ll explain it publicly, and hopefully no one will ask me again; a quick note to everyone though - this is the only post where i will discuss/explain this. If you want to have a conversation with me about it, or you just want to bitch and moan about what i say then you’ll have to send an ask OFF of anon, or use the PM system so we can talk (or trade insults, whatever) privately.

I am sourcing my information from here

“Contemporary scholars agree that “race” was a recent invention and that it was essentially a folk idea, not a product of scientific research and discovery. This is not new to anthropologists. Since the 1940s when Ashley Montagu argued against the use of the term “race” in science, a growing number of scholars in many disciplines have declared that the real meaning of race in American society has to do with social realities, quite distinct from physical variations in the human species. I argue that race was institutionalized beginning in the 18th century as a worldview, a set of culturally created attitudes and beliefs about human group differences

read that carefully, and consider the implications. That the entire concept of “race” that we are so familiar with is nothing more than a social construct; made and maintained entirely by our imaginations, and certain peoples’ (read: white peoples’) comfort with the groupings that it places them in.

Now i’ll give you one guess who came up with this asinine fever-dream; if you guessed anyone other than those responsible for the British/American slave-trade then no prize for you.

“Race and its ideology about human differences arose out of the context of African slavery.“
“When some Englishmen entered slave trading directly, it became clear that many of the English public had misgivings about slave-trading and re-creating slavery on English soil. It was an era when the ideals of equality, justice, democracy, and human rights were becoming dominant features of Western political philosophy.”

Now because of all those pesky citizens standing in the way of the ever so wonderful capitalist ideal of the “free market” something had to be done to calm their protest. Was the solution outlawing slavery, and giving honest pay for honest work?? You bet your ass it wasn’t!
Instead, those wily slavers and politicians began a long campaign to besmirch the image of “The African” (this would not only justify the enslavement of Africans in the public eye, but would also pacify newly-freed “white” slaves who were demanding a place in society with land to go with it by placing them above someone else in the social hierarchy which, up to that point, had been based entirely on Classism.)
The first shot fired was that Africans were, after all, just heathens and so it was the European moral duty as Christians to save their souls (by enslaving them, and putting them to work in “the service of god”, of course!)

“The major catalyst for this transformation was the rise of a powerful antislavery movement that expanded and strengthened during the Revolutionary Era both in Europe and in the United States. As a consequence proslavery forces found it necessary to develop new arguments for defending the institution. Focusing on physical differences, they turned to the notion of the natural inferiority of Africans and thus their God-given suitability for slavery.”
“By focusing on the physical and status differences between the conquered and enslaved peoples, and Europeans, the emerging ideology linked the socio-political status and physical traits together and created a new form of social identity. Proslavery leaders among the colonists formulated a new ideology that merged all Europeans together, rich and poor, and fashioned a social system of ranked physically distinct groups.“

“Thus was created the only slave system in the world that became exclusively “racial.” By limiting perpetual servitude to Africans and their descendants, colonists were proclaiming that blacks would forever be at the bottom of the social hierarchy.”

“From its inception separateness and inequality was what “race” was all about. The attributes of inferior race status came to be applied to free blacks as well as slaves. In this way, “race” was configured as an autonomous new mechanism of social differentiation that transcended the slave condition and persisted as a form of social identity long after slavery ended.”

I don’t think i have to quote anymore from that page (although i HEAVILY suggest you read through it yourselves - it’s not excessively long it’ll take you 5-10 mins, tops), i believe my point should be pretty obvious by now;

Racism was created as a new form of Classism (that’s right; an entire social structure - all encompassing; government, work, education, socialising. And that’s what it STILL is, today.) wherein “White” was the new “Upper-Class” and “Black” was the new “Lower-Class” and to be proud of being “White” is no more than saying “I’m proud that I am socially considered better than Black people, Latinxs, etc.”.

”But Merlin!” I hear a white person protest from the ether “White people can be low-income earners/lower class too! And POC can be High-income earners/Upper-class, after all, we just had a Black president!” To which I respond, READ THE FUCKING PAGE! But then calm down and explain that while this white person is technically correct they’re forgetting that it’s not so much about where individual POC and White people are positioned economically - it’s where they’re positioned in the public mindset.
An excellent example of this is the media; when a white person goes and shoots up a school, a church, etc. the media will show pictures of said white person smiling with friends or in a graduation outfit, or some other positive image and have descriptions of them as “nice, quiet, friendly, etc. etc.” and the reasons behind their actions are given as some form of mental issue.
But when it’s a POC not even having been found guilty of committing a crime, but having been shot by a cop and accused of committing a crime the pictures are of the POC in a hood, maybe throwing hand-signs, most likely with a serious face (interpreted as “intimidating” or “menacing”), along with accusations of drug use/possession, and labels of “thug” etc.

and if you aren’t willing to acknowledge that there’s an issue, and confront it - you ARE part of the problem.

TL:DR - don’t be proud of being white - the history of whiteness from it’s beginning to now is all bad, and all shameful. If you wanna be proud of your ancestry be proud of your ancestors; Be proud that you’re German, or Italian, or French, or whatever else. But none of those things equal being white, and you shouldn’t cling to a concept that says you are more important than everyone with a different skin-colour than you.

(disclaimer: this is my view alone (as a biracial German/Jew), and should never be used to invalidate or speak over POC and their opinions)

Changed: Part 10

Part 10: Seen

Summary: A/U in which the Reader is married to and has a child with Soldier!Steve.

Pairings/Characters: Steve x Reader, Bucky x Reader, Bucky x Natasha, Sam x Natasha, Peggy, OC Daughter – Emma

Warnings: Angst. Funerals. Death. Language. General Sadness. Smut. Panic attack. IDFK READER BEWARE.

A/N: Ok. Another short chapter. Hang in there. It’s about to go down, okay?BTW. THIS IS UNBETA’D and NOWHERE NEAR WHERE I WANTED IT TO BE SO BE GENTLE. 

Sitting alone on the couch, a dull ache washing over your heart.

What was that? Was Bucky cheating on you? Did Bucky fuck the babysitter? No. It couldn’t be. Could it? He’s the perfect man; loyal, intelligent, jaw dropping. Let it go.

Tapping your foot against the hardwood, your mind races, visualizing the worst possible scenarios.

Keep reading


People with disabilities can achieve anything that nondisabled people can. We can be the president, lead industry, teach, engineer, paint, write — these are things we have done already. I firmly believe seeing and engaging with disabled people helps combat internalized stigma.”

- Rebecca Cokley is the Executive Director of the National Council on Disability and a champion of disability and human rights.

Check out the in-depth Q&A with Rebecca below!

Keep reading


“ジョイントを渡す” by @acid.rar from the split album, “HIGH SOCIETY” with
#vaporwave #retro #80s #postvaporwave #electronic #experimental #psychedelic #gif #vaporfunk #tapewave #label #art #drugs #plunderphonics #eccojams #glofi #latenightlofi #vhs #420 #weed #stoner #baked #jazzwave #collab #music #cassette #splitalbum #acidrar #azuresands420 #powerlunchcorporation

Made with Instagram

anonymous asked:

hello, can i have this scenario “will you stop flirting with me you just got seriously injured and i’m the EMT trying to tend to your wounds in the ambulance, i don’t give a fuck that i look cute when i’m concerned, you’re lucky you’re not dead you dipshit” with kuroo and oikawa? thanks

bing bang bong here’s a long awaited scenario

Kuroo couldn’t feel his legs, the searing pain that’s supposed to come with the car crash, the broken shards of glass prickling at his skin, but he could feel the blood that ran down his forehead tickling his ear.

“Hello? Sir, can you hear me?” At first, he couldn’t, the voices that float above him was subsided by the ringing in his ear. He could only process the question and the owner of the voice after he opened his eyes, which instantly close after you shined a flashlight over him.

He produced a groan, temporarily blinded by the light on his face.

“Sir?” He tentatively opened his eyes, this time there was no sudden light, except for the tolerable amount of light lighting up the space he was in. Before him, was an unfamiliar face, the kind of face that you spot in a crowd and got your attention for an extra second more compared to other faces.

“Sir, are you aware of what happened to you?” Your face contorted to concern, and the longer Kuroo took to focus on you and how beautiful you would look if the frown that painted your face was replaced with a smile, the more he took notice of the siren blaring, muffled by the walls of the space he occupied, the various medical tools and labelled drugs in a small cabinet. He was in an ambulance.

“Yeah, I’m dead and now I’m welcomed with the face of an angel.” He wished his voice could’ve been in a better condition, he sounded like a choking frog, but you didn’t seem to care. You were busy, patching him up as best as you could, asking questions too fast for him to answer.

And then the flashlight was back on his face, this time Kuroo was prepared for it so he didn’t seem to mind it very much. He wasn’t prepared for you to lean in closer to him, just enough so the curtains of hair that fell brushed his cheekbones and swayed with each bumps that the ambulance pushed through.

“I need you to follow the light, okay?” Kuroo could understand your request, but he didn’t follow the light that moved to the right and left, his eyes were trained on you, a grin pulled at his lips seeing the panic on your face. He knew it was kind of mean of him to cause distress for you, but the last thing he needed was to fret over his condition, he needed something to distract him, and fortunately you were more than enough to do it.

“Oh no.” Cold fingertips peeled his eyelids wider, and Kuroo’s breath hitched for a moment at the contact. “Why would my eyes follow the light? I’m looking at something much brighter and prettier anyways.”

You retracted yourself from him and huffed, almost tempted to slap him for worrying you. 

“You’re injured, and on your way to a hospital, you could actually die.” Kuroo didn’t need that painful reminder, the stabbing pain on his torso was slowly getting to him already.

“At least I got to die next to someone so purrfect.” He felt accomplished upon hearing your choked laughter, and it helped distracted him from the increasing pain he’s now aware of.

“You’re a weird one, aren’t you?”

“I’d like to think the word you’re looking for is: hot to the extreme.”

“Ok, I think you need to shut up now, because that one was just terrible.”

“Only if you tell me your name, and promise to hold my hand when the doctor’s in.”

“Please tell me you have an off switch before I knock you out myself.”

Oikawa felt like an idiot for landing himself in an ambulance. He wasn’t aware of how hard he hit the pole—to be fair, Mattsun’s joke was really funny and Oikawa is known to be the ‘head banging laughter’ kind of guy—but he forgot all occurrences that happened after he laughed and before he got in the ambulance.

But he felt like an even bigger idiot for looking like an idiot who got injured in an idiotic way. Plus, the attractive person attending to him in the ambulance was quietly laughing at him whenever they turned their back to him.

“You’re so mean, laughing at an injured man.” He sighed dramatically while you slowly dabbed cotton drenched in alcohol on his injured head to sterilize the wound. Oikawa took this as a chance to heightened his drama queen act and yowl at the stinging pain.

You jumped, alarmed by Oikawa, “Oh, are you okay?” You were afraid that the injury was far deeper than it seemed and began checking on the wound to look for any other possible far worse injuries.

“Ah, I don’t think so, maybe you should kiss it better?”

A moment of silence passed, Oikawa’s exuberant and over confident smile has yet to disappear, even after seeing the indifference in your expression.

“You’re ridiculous, you might have suffered from some head trauma, that might explain this.”

His pout was adorable, but it was not something you should pay attention to. However, Oikawa was persistent, and will not give up before he redeems himself in your eyes.

“And now you’re insulting my personality? Why must the beautiful ones always be so cruel?”

“The same reason why you can’t be quiet and take this seriously, you’re in an ambulance, people usually panic over this.” Oikawa shrugged wiping off the blood that dripped from the tip of his curly brown hair. He was just fortunate that it wasn’t his arms or legs that got injured, if they did, perhaps Oikawa would’ve reacted differently towards the situation.

“It’ll heal. I’m a strong man you know, I play volleyball. But I can do other things to, like take pretty girls on dates they will surely enjoy.” He ended his line with a flirty wink, hopefully he still looked attractive with blood on his hair and a bruise on his forehead.

“And I have a syringe that I’m not afraid to use.” Oikawa didn’t think you were serious until you pulled one from your pocket, to which he pushed himself back and away from you, eyes wide in fear.

“If you can’t even handle a syringe, I don’t think you can handle me.”

Oikawa was silent for the whole ambulance ride, submissive to your orders and questions, he couldn’t believe he managed to make an even bigger fool of himself by being himself.

“Get rekt.” You whispered under your breath as Oikawa was rolled out of the ambulance in his stretcher, crying silently to himself about how ‘uncool’ he’s become.

One Direction (and Larry) happenings from February - May 2015

> Louis and Harry having a “toilet break” TWICE on stage

> ‘Always in my heart’ reaches one million

> Harold

> Louis became an egg

> Niall and Melissa rumors

> “I’m gay it’s pretty unfortunate”

> ”Loueh” “Oii Oii”

> Zayn cheating Rumors

> Zayn takes a “break” from the tour

> Elounor break up

> Louis “cheating” pictures released

> Zayn officially leaving One Direction 

> Louis’ twitter argument with Naughty Boy

> “I like vegetables” “Broccoli”

> Football with a towel (Louis and Harry) on stage

> “I think HIS is a better word”

> Louis helping Harry with his solo

> Larry Coca Cola AD

> One Direction leaving Modest! drama

> One Direction official twitter unfollowing Modest!

> The Sony leak

> Louis being more active on social media

> Zayn shaved his hair

> Zayn going to the Asian Awards and taking pictures with fans

> Louis posting in B&W on Instagram

> Louis clubbing

> Niall, Liam and Louis at the Gatsby Ball

> Louis gets his own record label

> Louis drugs scandal

> Louis and Liam fly to LA

> Louis and Harry supposedly out in LA together

> Naughty Boy and Louis twitter argument over a MacBook filter

> Zayns’ tweet to Louis

> #OhNoNiall

> News of one direction presenting on the Billboard Music Awards


> The Late Late show with James Corden

> Billboard pictures of Harry and Louis sat together for the show

> Harry and Louis NOT sat together

> #OhNoLiam

> Other Coca Cola ADs with all of the boys (except Larry)

> Louis pictured with Taylor

> #AlwaysInMyHeartLarry

> Niall and Jade rumors

> Britain’s Got Talent with Niall and Louis

> Harry supposedly bought Louis a t-shirt

> Louis and Lauren spotted together

> Zerrie break up rumors

> Rumors of Zayn returning to the band

> #OhNoLouis

And that’s it so far. Add on things I missed or send me an ask so that I can include them in the correct order. This just proves how much the One Direction Fandom go through…