degenerative condition

How the food you eat affects your brain

If you sucked all of the moisture out of your brain and broke it down to its constituent nutritional content, what would it look like? Most of the weight of your dehydrated brain would come from fats, also known as lipids. In the remaining brain matter, you would find proteins and amino acids, traces of micronutrients, and glucose. The brain is, of course, more than just the sum of its nutritional parts, but each component does have a distinct impact on functioning, development, mood, and energy. So that post-lunch apathy, or late-night alertness you might be feeling, well, that could simply be the effects of food on your brain.

Here are four fascinating facts about your brain on food!

Your brain runs on fats! The good kinds, that is. As we mentioned before, your brain is made mostly of fats. Of the fats in your brain, the superstars are omegas 3 and 6. These essential fatty acids, which have been linked to preventing degenerative brain conditions, must come from our diets. So eating omega-rich foods, like nuts, seeds, and fatty fish, is crucial to the creation and maintenance of cell membranes.

Food can make you super sleepy! But, it can also keep you up. Proteins and amino acids, the building block nutrients of growth and development, manipulate how we feel and behave. Amino acids are one of the reasons we might feel calm after eating a large plate of pasta, or more alert after a protein-rich meal. While the human brain only makes up about 2% of our body weight, it uses up to 20% of our energy resources. Most of this energy comes from carbohydrates that our body digests into glucose, or blood sugar. The frontal lobes are so sensitive to drops in glucose, in fact, that a change in mental function is one of the primary signals of nutrient deficiency. Carbs come in three forms: starch, sugar, and fiber. While on most nutrition labels, they are all lumped into one total carb count, the ratio of the sugar and fiber subgroups to the whole amount affect how the body and brain respond. A high glycemic food, like white bread, causes a rapid release of glucose into the blood and then comes the dip. Blood sugar shoots down, and with it, our attention span and mood. On the other hand, oats, grains, and legumes have slower glucose release, enabling a steadier level of attentiveness. For sustained brain power, opting for a varied diet of nutrient-rich foods is critical.

Trans fats are not your friends. While omegas are good fats for your brain, long-term consumption of other fats, like trans and saturated fats, may compromise brain health. Some research shows that trans fats may impair your memory and may actually affect the size of your brain??!?

Food affects your mood. The complex combinations of compounds in food can stimulate brain cells to release mood-altering norepinephrine, dopamine, and serotonin. But getting to your brain cells is tricky, and amino acids have to compete for limited access. A diet with a range of foods helps maintain a balanced combination of brain messengers, and keeps your mood from getting skewed in one direction or the other.

How’s that for ‘food for thought’?

From the TED-Ed Lesson How the food you eat affects your brain - Mia Nacamulli

Animation by Private Island

The brain above illustrates the degenerative changes and atrophy caused by Creutzfeld-jakob Disease, a form of transmissible spongiform encephalopathy. When ‘mad cow disease’ is transmitted to humans it is classified as a varient of CJD. Typically CJD is transmitted through exposure to infected tissue usually through medical procedures, however there can be a other causes - such as hereditary CJD. A person is infected with a type of protein known as a ‘prion’, these occur normally within humans but the infectious form is folded in an abnormal way, which then alters normal, healthy prions in the cells of the host.  It is thought that the neuronal loss and damage is caused by a build up of these proteins in the brain.

CJD is marked by a quick onset of neurological symptoms and a rapidly progressing dementia and decline of neurological functioning. Initially, individuals experience problems with muscular coordination; personality changes, including impaired memory, judgment, and thinking; and impaired vision. People with the disease also may experience insomnia, depression, or unusual sensations. As the illness progresses, mental impairment becomes severe. Individuals often develop involuntary muscle jerks called myoclonus, and they may go blind. They eventually lose the ability to move and speak and enter a coma. CJD is fatal, and there are no treatments for the condition. 

anonymous asked:

I absolutely adore Bree Amell; her lightness, energy and compassion. I was wondering, in the worst-case Cullen scenario. what would Bree do if she was the one to find him begging on the streets? Based on what I've read so far I headcanon that she would do her best to try and cure him, even if it was ultimately futile

Thank you so much for your kind words! They made my week! ;V;

I think Bree’s desire would be to reunite him with his family. If that’s not an option, I think her next step would be to offer him refuge in her house if that’s something Cullen would want in that moment. Considering that Bree is also suffering from a fatal degenerative condition as a Warden, I think she’d be sensitive to Cullen’s agency and will.

What if, due to all of the unprotected blows to the head from Joker abusing him at the asylum, Jason develops CTE (chronic traumatic encephalopathy)? The degenerative disease that occurs from suffering from a lot of traumatic brain injuries. Sure, he’s fine during the course of the game’s events (as far as degenerative brain conditions go, at least), but what if he were to develop it down the road? A life of continued vigilantism isn’t exactly doing him any favors. 

In some cases, CTE can present as Alzheimer’s. At first, Jason can easily brush off the symptoms as just being part of his PTSD. I mean, mood swings and impulsive behavior aren’t exactly unusual for him. But then he notices his memory beginning to deteriorate. He starts forgetting where he’s just placed something, then flat out forgets where things are – places they’ve always been. Then what he was doing earlier that day, or what he just said before. His mind becomes hazy, and it starts taking him longer to find simple solutions to problems and it’s difficult for him to concentrate on tasks. He doesn’t feel as sharp anymore, and he picks up on the gradual change in his personality over time. He has no other choice than to eventually give up his crusade against crime, and with that comes an emptiness. A lack of purpose. It feels as if his sense of self – the small shred of Jason Todd that he’s managed to regain after his confrontation with Bruce – is slipping through his fingers. He so desperately tries to cling onto whatever he has left, but knows he’s failing, and he’s absolutely terrified. Because he knows that all his hard work, all his battles with himself in order to reach a catharsis and finally feel a bit like himself again, may have been for nothing. He’s stricken with an overwhelming fear that, someday in future, he might not even know who he is anymore. But the worst part – the part that’s almost nauseating to him – is the idea that the Joker would inevitably win. Unintentionally, he will have stripped him of absolutely everything all over again, indefinitely. 

Human Central Nervous System and Peripheral Nervous System Connections

The central nervous system (CNS) of the human consists of the brain, spinal cord, and cranial nerve II (the optic nerve which connects to the eyeball).

When compared to the peripheral nervous system (PNS), the CNS differs in several key ways. It’s largely autonomic (requires no input for it to work) instead of voluntary, is much more protected (by bone and the blood-brain barrier), and interprets input, rather than integrating it.

As the PNS is much less protected, it’s vulnerable to damage by toxins, disease, mechanical injury, and autoimmune disorders. The degenerative conditions of the CNS are almost always hereditary.

Dictionnaire Universel d'Histoire Naturelle. Charles d'Orbigny, 1849.

All I’ve ever wanted was to be normal, but that was never in the cards for me.

12 years ago, I sprained both ankles in a two-week period. I didn’t know it yet, but this was due to weakened joints from a genetic disorder that had been in my body since birth. As a result of these injuries, I had to abandon my spot on the crew team and stop swimming. I would never walk the same again.

6 years ago, right after I graduated from college, I could barely walk. I struggled to get from my apartment to a pharmacy only two blocks away; I’d often have to drive there. One short workout would put me on bed rest for a week.

4 years ago today (June 20th, 2013) I was finally diagnosed with Ehlers-Danlos Syndrome (EDS), a degenerative condition that manifests in my connective tissue and leads to subluxations, chronic pain, and a host of other symptoms.

Soon after that, diagnosis in hand, I started physical therapy and slowly brought my mobility back.

Today, I am stronger than I ever have been. I can swim 1.1 miles in 25 minutes, run 2 miles in the same, lift weights (little ones, but still), and walk without my wheelchair or cane.

I still have the condition and I still have the chronic pain, but I was able to work and improve and get myself to this point.

EDS is degenerative; there’s only so much I can control. Eventually this condition will get worse - it already has in some parts of my body. What I’m doing today is strengthening what I can to combat faster degeneration, building muscle around my ligaments to support them and keep them in place, and working to keep myself as mobile as possible.

I may not be ‘normal,’ but I can be strong.

[image description: a woman (me) standing outside, smiling and wearing a backwards grey hat, sunglasses, a black tank top that says ‘THE FUTURE IS ACCESSIBLE’ in white letters, a red checkered flannel, and denim shorts.]

lovelytornado  asked:

I found your blog from the everything-wrong-with-horses post, but I've been devouring the dog breed posts. Could you make one about bullmastiffs? I really want one bc my childhood bullmastiff was the sweetest and most loving dog I have ever met, but my bf doesn't like brachycephalic dogs & says a lab would be healthier. Thanks for any insight!

I can certainly talk about them a little bit. While they’re probably not going to live quite as long as a Labrador would, I would hesitate to assume a lab would be healthier because of the muzzle. Bullmastiffs are considered brachycephalic, but they’re on the less extreme side and don’t suffer Brachycephalic Airway Syndrome as often as the more extreme breeds.

But first, please note the disclaimer. These posts are about the breed from a veterinary viewpoint as seen in clinical practice, i.e. the problems we are faced with. It’s not the be-all and end-all of the breed and is not to make a judgement about whether the breed is right for you. If you are asking for an opinion about these animals in a veterinary setting, that is what you will get. It’s not going to be all sunshine and cupcakes, and is not intended as a personal insult against your favorite breed. This is general advice for what is common, often with a scientific consensus but sometimes based on personal experiences, and is not a guarantee of what your animal is going to encounter in their life.

Originally posted by jayne-n-pals

While the individuals I’ve encountered of this breed have been nice enough dogs, they’re not overly common down here, especially compared to the Bull Arab, which is an Australian breed that is arguably better suited fr our climate, but there’s a few of them around.

Hip Dysplasia and Elbow Dysplasia are major concerns for this breed, as they are with most large breed dogs. When these joints fail to develop properly, they can lead to persistent and potentially severe lameness from a young age. While many dogs do get surgical treatment, it’s expensive and should be considered when looking at this breed.

Now, I’ve said many times before that I’m not a fan of painful eyes, and the extra skin on these dog’s heads thanks to that bulldog heritage will frequently contribute to Entropion, where the eyelids roll inwards, rubbing eyelashes and fur against the eyeballs. This is painful and requires surgery.

Brachycephalic Airway Syndrome, which is the name we give to the cluster of symptoms associated with having a muzzle that is too short, is present in this breed, but not ubiquitous. Some individuals are better than others, and while it’s hard to tell by looking at a puppy whether it will have an issue or not, puppies with more open nostrils are likely to be less affected.

Cerebellar Abiotrophy is noted in the breed, a degenerative neurological condition which often affects quite young dogs where they become progressively less and less coordinated. It’s relatively rare, but is easy to confuse with Wobbler Syndrome (Cervical vertebral instability), where the vertebrae of the neck occasionally compress the spinal cord, causing weakness to paralysis in the rest of the dog. This condition is more common in large, rapidly growing breeds.

Big, deep chests predispose this breed to Gastric Dilatation Volvulus (GDV), where the stomach twists on itself, cutting off blood supply and the outflow to both the oesophagus and the small intestine. You only have a few hours to get them to surgery, or they will die.

Less dramatically, most of the time they come into the clinic for some sort of skin issue, whether it’s allergies or some sort of infection.

an mags & luce interaction that popped into my head, abt them getting older that i kinda want to write as a drabble? it’s specifically about magnus getting one of his knees replaced and lucretia hanging out with him while he recovers. 

but the text is as follows:

Magnus: Remind me again why Merle can’t be assed to cleric the shit out of my knee?

Lucretia: You developed a degenerative condition. It would’ve only continued to deteriorate under wear and tear no matter how many times he healed it. And he’s still mad you cut his arm off, so, are you willing to run the risk of his surgical prowess? 

I’ve spent so much of my time since my arterial rupture, neck deep in the medical system; barely treading water, but it’s gotten me so far. Things are getting close to as under control as they’ll probably ever be, given that my conditions are degenerative and progressive.

It’s time to really pull things around and live as hard as I can again. I think I’ve always done as much as I can to be authentically me, but this year I’m determined to get back some of what I’ve lost (whatever small amount I can). It’s time to restore balance.

I’ve already come so far in the past 3-4 months and after spending hours again this week wrapped up in medical stuff sapping my energy, I’m once again reflecting on when I can finally direct all my energy to my passions again. I may never have that luxury again, and I have to be okay with that, but what I’ve been pushing for this entire time, Quality of Life, is all about having the energy, time and freedom to have a life outside of the medical complex.

I’m almost there. I can feel it.

{please don’t remove my words}

Crystals and Colours

Source: [“The Complete Crystal Handbook” by Cassandra Eason]

The color of a crystal is one of the easier ways of identifying the right crystal for specific healing, personal empowerment, or protection purposes. If a color is “hot” like red – associated with life blood and fire – its action will be dynamic, fast, and go straight to the root of a problem. In contrast, a green crystal represents gradual growth and nature, linked to a slow but continuing increase in any area of life. The shade of a crystal can also offer clues: a sparkling transparent clear quartz crystal, reflecting sunlight, has different energies and vibrations than a cloudier shimmering white selenite that resembles moonlight.

The power of a crystal can be enhanced by placing it near a burning candle of a similar color. It could be beneficial to build up a collection of crystals in different shades and intensities of brightness in the same color, such as soothing transparent purple amethyst and brighter opaque sugilite that is still gentle but faster acting. Feel free to try using “antidote” colors as well; for example, draw on the power of a blue crystal if someone is very angry or a situation is too fast moving.

The following are “traditional” color association for crystals and their uses. These correspondences should be used as suggestions or ideas, and are by no means concrete or absolute; personal associations within magic are generally more powerful, though these correspondences are a good base to gain inspiration or work from.

Disclaimer: This information should not be used as a substitute for medical treatment or advice, or as a means of diagnosis. If you have - or suspect you may have - a medical condition, please consult a healthcare professional immediately. The home remedies included here should not be used to diagnose, treat, prevent, or cure any illness.

* Some of the “healing powers” sections mention specific body parts and ailments that may be triggering for some parties, so please be wary reading through.

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Oof I’ve had the most rotten migraine since yesterday’s appointment. Just checking in to say, Happy Wheelchair Day! I had to overcome a lot of internalized ableism and self worth struggles before I finally agreed to try using a wheelchair. I was progressively housebound for almost two years before I managed to get to that point mentally. Having degenerative conditions and growing up surrounded by subtly and quietly ableist attitudes and worlds is quite a different situation to being injured or indeed growing up with the use of a wheelchair. All situations have their own challenges… My own was very much internal.

When I finally let my doctors know I was ready for a wheelchair they seemed relieved and very encouraging. Clearly they had been thinking it, but again, likely due to society’s ableist ideas had been reluctant to suggest it. My entire life has changed since I ‘succumbed’ to rolling around and it is 100% for the better. I feel so free and positive these days. I feel like I’m getting a huge part of myself back (and my upper body strength is the best it’s ever been which for someone with muscular and joint problems is a big deal!).

While I was absolutely housebound I strongly resent the phrase 'wheelchair bound’ I am a wheelchair user. It gives me freedom and life. It gives me the ability to participate and enjoy most things I want to. Only society is to blame for any barriers I face as a wheelchair user. I’m still anxiously awaiting my new chair that will hopefully fit me like a fancy glove, and I will write more then, but for now, here is a photo of me about a month ago, my first time on a gravel 'trail’.

{please don’t remove my words}


new for fall i have double layered noise muffling beanies and super soft SUPER insulating headbands! i have no money, am autistic, and have a degenerative spinal condition. these awesome headgear protect your ears from unfriendly sounds and are sensory friendly and extremely comfortable!

please reblog i have no money and my anxiety is through the roof because my business is failing


anonymous asked:

Is EDS degenerative? Does it get worse as you get older? I've seen people claim both taht it gets worse and that it gets better as your joints get stiffer? Do you knw which one it is or is it just different fr different people?

It’s my understanding that some of the experts in the field (specifically I believe I heard this from Dr Grahame at the last EDNF National Conference) are hoping to label EDS as sort of a conditional degenerative syndrome. That’s my horrible mis-wording of his term I’m sure. Basically, what he’s suggesting is that the longer one goes undiagnosed and without proper care, education, and support for joint protection the greater the risk long term disability and degeneration. So like many of us, if you spent much of your life doing high impact activities and had no idea that your joints and tissues were not functioning properly so you had no joint protection or had improper/inadequate joint protection, the more risk there is for damage. (Now toss those, athletic or not,  in who have had surgery that fail because no one knew they had EDS) They want to add this to the EDS definition to stress the importance of early screening and diagnosis. 

I have heard the mixed pot of middle aged and or post menopausal responses as to whether things get worse or better, as well. Personally, I take both with a grain of salt although given my personal life history I tend not side eye those who are certain that things will be better for me in my old age. So, I do think that it is going t be different person to person. I know people older than me and younger than me who haven’t been in competitive sports or intensely active through out life in anything too high impact and have only since diagnosis started an exercise program and they seem to have very few issues with what works for them and their rate of improvement. I know people who haven’t been in competitive sports etc and they are just injury after injury and just completely different from me in rate at which they feel things are getting bad even though I was a lot rougher on my body. I mean it goes for healthy folks too, the more waer and tear they do, the more they don’t take good care of their bodies, the rougher aging is. Unfortunately for us we have the added issues of a system of faulty structures holding us together to begin with.  So it seems to me to be different for everyone depending on many many factors but I do feel like that early diagnosis and proper care early on is a huge, huge piece of the puzzle. And we are a huge puzzle, aren’t we?! Haha! ;)

Feel like this was maybe a bit rambley, disjointed (no pun lol), but hopefully it makes some sense and helps a bit.  And hopefully this summer at the big shot summit (that’s what I’m calling it because fog. It’s a summit of the big shot EDS doctors and other medical professionals etc.) as they are fine tuning the categories, definitions, and diagnosis processes, hopefully there will be more information, explanation, and investigation into degeneration and aging in Ehlers-Danlos Syndrome. 

Okay, deep breath. If you’ve read the acknowledgments in Six of Crows, you may know I have a degenerative condition that makes walking pretty painful. It’s called avascular or osteonecrosis and it showed up in my 20s. Pretty unusual for someone my age and in good health, but there you have it. Some days are easy, some days every step hurts like hell. The hardest part is not being able to do things I used to really love in the same way. Dancing, exploring cities on foot, running— ok, I never loved running, but you get the idea.

 Anyway, I realized my (ableist) reluctance to use a cane has meant missing out on a lot of good things, and that is some serious bs. So for the last leg (hey o!) of the Magic and Mayhem tour, you may see me with my @dellamorteco cane (technically a raven’s skull, Kaz would not approve) or my @lekiusa hiking cane.

 I’m not great at talking about personal stuff on social media, but I’m trying to be more up front about the situation. It’s part of the reason I wrote Kaz, and it’s not something I’m interested in hiding. My plan is to acquire a lot of awesome walking sticks and to be as candid as possible about the good days and the bad days. Thanks for letting me share both. And my sweet new mani.

6 Superfoods Your Body Will Love!

We should all eat a varied and balanced diet but there are a few ingredients that are exceptionally good for you. Our mate Layla shows us some of the ones everybody’s talking about right now… with the help of Jamie… in a Morph suit!

Grab a sneak preview of today’s video, then check out a bit more info on each food below! :) 


- The wide selection of healthy fats and nutrients found in avocados – (oleic acid, lutein, folate, vitamin E, monounsaturated fats and glutathione to name a few) can help protect your body from heart disease, cancer, degenerative eye and brain diseases.

- Avocado is one of the best sources of beta-sitosterol from a whole food. It’s basically a healthier version of animal cholesterol and your body prefers to use it if both are present, therefore lowering cholesterol in the blood and as a result reducing heart disease.

- The Brazilian football team enjoyed a sweetened avocado smoothie for breakfast during the world cup as it gives a slow release of healthy fats and proteins throughout the day.

- Be careful though… the avocado is also the UK’s most dangerous fruit. There are more admittances to A&E because of avocado preparations than any other fruit!


- A gluten-free plant from Ethiopia. The smallest grain in the world… about the same size as poppy seeds. 

- Teff has 5x more calcium than wheat so is ideal to those on dairy-free diets. 

- Not just that, but teff contains the full range of eight amino acids essential for humans, so is excellent for vegetarians. 

- The grain is pretty versatile too and can be added to breads, biscuits and savoury dishes likes stews, casseroles or soups.


- This is currently classed as the most nutrient dense superfood… otherwise called a ‘Powerhouse Fruit and Vegetable’. This means it has , on average, 10% or more daily value per 100 kcal of all 17 qualifying nutrients.

- It’s a good source of loads of vitamins and minerals such as Vitamin A,K and C which are brilliant for maintaining healthy hair, eyes, skin and nails.

- Plus, it’s got stacks of iron, calcium, potassium and also phytochemicals and antioxidants which provide protection against heart disease, cancer and other degenerative conditions

- It is also beneficial in treating cough, bronchitis and constipation and improves general appetite and digestion.

Chia Seeds

- Chia seeds are probably the most trendy right now. They’ve become a bit of a celeb superfood, but also popular among athletes at the commonwealth games.

- They are high in fibre which most can help prevent heart disease, diabetes, weight gain, some cancers, and improve digestive health. 

- Chia seeds have 15 x more magnesium than broccoli and 8 x times more Omega 3 than salmon. Both of which are handy for contributing towards healthy cognitive brain function.

Maca Root

- We had ours as a powder which is ground up from the Maca Root which grows in the Andes in Peru.

- It’s super high in Vitamin B2, C, Calcium, Copper, Iron and Zinc.

- These vitamins and minerals helps your body with fertility, libido and menopausal health.

- It can also reduce tiredness meaning you can enjoy life more as you’re full of energy. 

- Also brill for sexual health… thanks to the Zinc in Maca which contributes to normal fertility and reproduction.

Acai berries

- A natural berry native to South America that has a taste somewhere between blueberries and chocolate

- The berries have a phenomenal concentration of antioxidants that help combat premature aging, with 10 times more antioxidants than red grapes. So if the doctors say a glass of red wine a day is good… just think what Acai berry juice could do!

- Acai is particularly high in the antioxidant Glutathione, which plays an important role in carcinogenic detoxification (I.e. It’s anti-cancer fighting).


Facing Fears with Dark Art Artist @standarkart

To discover more dark art, and experience the world through Stanislav’s eyes, follow @standarkart on Instagram.

Born with cerebral palsy and suffering from a degenerative eye condition, Ukrainian Stanislav Krawczyk (@standarkart) remembers his childhood as a constant battle. Confined and isolated by hospital walls, Stanislav developed the urge to express himself, and by the age of 13, he knew he wanted to become an artist. In art, particularly dark art, he found a way to echo his emotions and channel his inner chaos and pain.

“Dark art for me is a more radical form of surreal,” he says. “If surreal is the combination of dream and reality, dark art is the combination of reality and nightmares.” One year ago, Stanislav left his home country and joined likeminded artists in Los Angeles in order to start a new, self-determined life. “I was just a blind disabled in the Ukraine,” he says. “Here I am part of the dark art society and cultural life of the city. And the main thing is, I can make a living. I have friends, a lot of friends, and I’m not alone.”

Ethan’s Awful Life

I can’t stop thinking what a terrible time it’s been for Ethan the last few months. I mean jesus.

His brother steals from him.

His brother finds out he’s a dad so Ethan has a baby thrust upon him and his flat and his life.

The baby isn’t Cal’s and she is taken away from them.

He loses confidence in his work after Olivia and Jess.

He tries to deal with it and then a patient kills himself and he feels responsible.

He resigns from his job.

Changes his mind and realises he should stick it out.

Finds out his mother isn’t his real mother and his birth mother has a genetic degenerative life shortening condition.

Finds out his brother lied about it to him for months.

Finds out she’s dying imminently.

His mother dies and he finds out he has been tested for the disease behind his back and subsequently has the gene.

Bloody hell. Poor guys it’s surprising and a testament to his character that he hasn’t had a breakdown yet. Seriously. Talk about a series of unfortunate events.

And cal has the audacity to say Ethan lives in an ‘antiseptic Ethan bubble’ where he 'loves to control everything’ well can you blame the poor guy? His life is always trying to break him no wonder he tries as hard as he can to control that.