COS7 cells transfected with DCX DsRed and MPR GFP.

The COS-7 cell line was derived from the kidney of the African Green Monkey, Cercopithecus aethiops. The cells themselves most resemble fibroblast cells in humans and are thus often called COS-7 monkey fibroblast or COS-7 fibroblast-like cells. COS-7 cells are not primary cells. The CV-1 cell line was initiated in the 1960s from an African Green Monkey Kidney. In the early 1980s, the COS-7 line was developed from the CV-1 line by Yakov Gluzman through transformation with a Simian Vacuolating Virus 40 (SV40), a virus that codes for the wild type virus T-antigen. (Info :